TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 523.685 | Formula: C19H15BrClF3N2O5
H donors: 0 H acceptors: 3 LogP: 4.71 Rotable bonds: 11
Rule of 5 violations (Lipinski): 2
SMILES: CCOCCOC(=O)C(=O)OCn1c(c2ccc(cc2)Cl)c(c(c1C(F)(F)F)Br)C#N
InChi: 1S/C19H15BrClF3N2O5/c1-2-29-7-8-30-17(27)18(28)31-10-26-15(11-3-5-12(21)6-4-11)13(9-25)14(20)16(26)19(22,23)24/h3-6H,2,7-8,10H2,1H3
InChiKey: IAIAYIRDSWOUAX-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Echinococcus multilocularis	FL cytokine receptor	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0095	0.0051	0.5
Echinococcus granulosus	activated cdc42 kinase 1	0.0095	0.0051	0.5
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0095	0.0051	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	serine/threonine kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Schistosoma mansoni	protein kinase	0.0095	0.0051	1
Giardia lamblia	Protein 21.1	0.0095	0.0051	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0095	0.0051	0.5
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0095	0.0051	0.5
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0095	0.0051	0.5
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0095	0.0051	0.5
Echinococcus granulosus	epidermal growth factor receptor	0.0095	0.0051	0.5
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	epidermal growth factor receptor	0.0095	0.0051	0.5
Echinococcus granulosus	receptor type guanylyl cyclase	0.0095	0.0051	0.5
Entamoeba histolytica	hypothetical protein	0.0095	0.0051	0.5
Schistosoma mansoni	protein kinase	0.0095	0.0051	1
Echinococcus granulosus	tyrosine kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Schistosoma mansoni	protein kinase	0.0095	0.0051	1
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus granulosus	raf serine:threonine protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine kinase	0.0095	0.0051	0.5
Schistosoma mansoni	protein kinase	0.0095	0.0051	1
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus granulosus	c src tyrosine kinase	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosin kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Giardia lamblia	Kinase, NEK	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	protein tyrosine kinase	0.0095	0.0051	0.5
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0095	0.0051	0.5
Onchocerca volvulus		0.3431	1	1
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase pr2	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosin kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Echinococcus multilocularis	protein kinase	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0095	0.0051	0.5
Trichomonas vaginalis	TK family protein kinase	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine kinase	0.0095	0.0051	0.5
Entamoeba histolytica	hypothetical protein	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0095	0.0051	1
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	ankyrin repeat protein	0.0095	0.0051	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0095	0.0051	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0095	0.0051	0.5
Plasmodium falciparum	tyrosine kinase-like protein	0.0095	0.0051	0.5
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0095	0.0051	0.5
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase csk	0.0095	0.0051	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0095	0.0051	0.5
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0095	0.0051	0.5
Entamoeba histolytica	serine/threonine kinase, putative	0.0095	0.0051	0.5
Schistosoma mansoni	serine/threonine RGC	0.0095	0.0051	1
Echinococcus granulosus	tyrosine kinase	0.0095	0.0051	0.5
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0095	0.0051	0.5
Entamoeba histolytica	hypothetical protein	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Schistosoma mansoni	protein kinase	0.0095	0.0051	1
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0095	0.0051	0.5
Schistosoma mansoni	protein kinase	0.0095	0.0051	1
Trypanosoma brucei	Prostaglandin E synthase	0.3431	1	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine- protein kinase 2, putative	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0095	0.0051	0.5
Echinococcus granulosus	epidermal growth factor receptor	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Schistosoma mansoni	serine/threonine protein kinase	0.0095	0.0051	1
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0095	0.0051	1
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Schistosoma mansoni	protein kinase	0.0095	0.0051	1
Entamoeba histolytica	hypothetical protein, conserved	0.0095	0.0051	0.5
Giardia lamblia	Kinase, NEK	0.0095	0.0051	0.5
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Plasmodium falciparum	protein kinase, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	STE family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0095	0.0051	1
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Plasmodium falciparum	protein kinase, putative	0.0095	0.0051	0.5
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Entamoeba histolytica	tyrosin kinase, putative	0.0095	0.0051	0.5
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0095	0.0051	0.5
Entamoeba histolytica	hypothetical protein	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0095	0.0051	0.5
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	protein kinase	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Schistosoma mansoni	ephrin receptor	0.0095	0.0051	1
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	serine/threonine kinase, putative	0.0095	0.0051	0.5
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0095	0.0051	1
Trypanosoma cruzi	glutathione-S-transferase/glutaredoxin, putative	0.3431	1	1
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Schistosoma mansoni	protein kinase	0.0095	0.0051	1
Loa Loa (eye worm)	hypothetical protein	0.3431	1	1
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0095	0.0051	0.5
Schistosoma mansoni	serine/threonine protein kinase	0.0095	0.0051	1
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0095	0.0051	0.5
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0095	0.0051	1
Echinococcus multilocularis	activin receptor type	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0095	0.0051	0.5
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trypanosoma cruzi	glutathione-S-transferase/glutaredoxin, putative	0.3431	1	1
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0095	0.0051	0.5
Toxoplasma gondii	prostaglandin-E synthase	0.3431	1	1
Trichomonas vaginalis	conserved hypothetical protein	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	hypothetical protein	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase csk	0.0095	0.0051	0.5
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0095	0.0051	0.5
Entamoeba histolytica	serine/threonine kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	heat shock protein 70	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Entamoeba histolytica	cysteine surface protein, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Plasmodium vivax	protein kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	hypothetical protein	0.0095	0.0051	0.5
Entamoeba histolytica	hypothetical protein	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Schistosoma mansoni	hypothetical protein	0.0095	0.0051	1
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0095	0.0051	0.5
Echinococcus granulosus	natriuretic peptide receptor 1	0.0095	0.0051	0.5
Entamoeba histolytica	hypothetical protein	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase csk	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	protein kinase atn1, putative	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Schistosoma mansoni	serine/threonine protein kinase	0.0095	0.0051	1
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase shark	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	serine/threonine kinase, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	integrin linked protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	epidermal growth factor receptor	0.0095	0.0051	0.5
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase with ankyrin repeats, putative	0.0095	0.0051	0.5
Echinococcus granulosus	integrin linked protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0095	0.0051	0.5
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0095	0.0051	0.5
Echinococcus granulosus	activin receptor type	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine protein kinase	0.0095	0.0051	1
Schistosoma mansoni	ephrin receptor	0.0095	0.0051	1
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0095	0.0051	0.5
Echinococcus granulosus	ephrin type A receptor 4 A	0.0095	0.0051	0.5
Giardia lamblia	Kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0095	0.0051	0.5
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0095	0.0051	0.5
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	hypothetical protein	0.0095	0.0051	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0095	0.0051	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Schistosoma mansoni	protein tyrosine kinase	0.0095	0.0051	1
Echinococcus granulosus	tyrosine protein kinase csk	0.0095	0.0051	0.5
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	transfer RNA-Thr	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0095	0.0051	0.5
Schistosoma mansoni	protein kinase	0.0095	0.0051	1
Entamoeba histolytica	receptor protein kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	serine/threonine kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Echinococcus granulosus	protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase shark	0.0095	0.0051	0.5
Echinococcus granulosus	protein tyrosine kinase	0.0095	0.0051	0.5
Entamoeba histolytica	hypothetical protein	0.0095	0.0051	0.5
Entamoeba histolytica	receptor protein kinase, putative	0.0095	0.0051	0.5
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Echinococcus multilocularis	c src tyrosine kinase	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Trichomonas vaginalis	conserved hypothetical protein	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0095	0.0051	0.5
Echinococcus multilocularis	insulin receptor	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0095	0.0051	0.5
Leishmania major	glutathione-S-transferase/glutaredoxin, putative	0.3431	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Plasmodium falciparum	tyrosine kinase-like protein	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0095	0.0051	1
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus granulosus	kinase suppressor of Ras 1	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase Srms	0.0095	0.0051	0.5
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0095	0.0051	0.5
Echinococcus granulosus	activated cdc42 kinase 1	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase csk	0.0095	0.0051	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus granulosus	insulin receptor	0.0095	0.0051	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Schistosoma mansoni	protein kinase	0.0095	0.0051	1
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Trichomonas vaginalis	TKL family protein kinase	0.0095	0.0051	0.5
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0095	0.0051	0.5
Schistosoma mansoni	protein kinase	0.0095	0.0051	1
Entamoeba histolytica	ankyrin repeat protein	0.0095	0.0051	0.5
Trichomonas vaginalis	AGC family protein kinase	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosin kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase Blk	0.0095	0.0051	0.5
Schistosoma mansoni	tyrosine kinase	0.0095	0.0051	1
Schistosoma mansoni	serine/threonine protein kinase	0.0095	0.0051	1
Echinococcus granulosus	tyrosine protein kinase HCK	0.0095	0.0051	0.5
Echinococcus multilocularis	activated cdc42 kinase 1	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine kinase	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0095	0.0051	0.5
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.0051	0.5
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase, putative	0.0095	0.0051	0.5
Plasmodium falciparum	protein kinase, putative	0.0095	0.0051	0.5
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5
Entamoeba histolytica	hypothetical protein	0.0095	0.0051	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0095	0.0051	0.5
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0095	0.0051	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0095	0.0051	0.5

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2228519

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1813937