TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 344.359 | Formula: C19H20O6
H donors: 1 H acceptors: 2 LogP: 3.77 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: COc1c(OC)ccc(c1OC)/C=C/C(=O)c1c(O)cccc1OC
InChi: 1S/C19H20O6/c1-22-15-7-5-6-13(20)17(15)14(21)10-8-12-9-11-16(23-2)19(25-4)18(12)24-3/h5-11,20H,1-4H3/b10-8+
InChiKey: PPOLDGGJGCRDIM-CSKARUKUSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus granulosus	arachidonate 5 lipoxygenase	0.0054	0.1401	0.237
Echinococcus granulosus	7tm_1 domain containing protein	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Leishmania major	hypothetical protein, conserved	0.0025	0.0217	0.5
Echinococcus multilocularis	g protein coupled receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	myosin xvIII	0.0042	0.0918	0.1552
Onchocerca volvulus		0.0042	0.0918	0.1552
Echinococcus granulosus	nmda type glutamate receptor	0.0085	0.2669	0.4515
Trichomonas vaginalis	glucosylceramidase, putative	0.0252	0.9418	1
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0042	0.0918	0.1552
Echinococcus granulosus	neuropeptide s receptor	0.0042	0.0918	0.1552
Trichomonas vaginalis	glucosylceramidase, putative	0.0252	0.9418	1
Echinococcus granulosus	tm gpcr rhodopsin	0.0042	0.0918	0.1552
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Echinococcus multilocularis	Glutamate receptor, ionotropic kainate 3	0.0027	0.0325	0.055
Brugia malayi	putative neuropeptide receptor	0.0042	0.0918	0.0918
Echinococcus multilocularis	arachidonate 5 lipoxygenase	0.0054	0.1401	0.237
Brugia malayi	AKH receptor	0.0042	0.0918	0.0918
Echinococcus multilocularis	geminin	0.0165	0.5912	1
Brugia malayi	Dopamine receptor protein 2	0.0042	0.0918	0.0918
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.0918	0.1552
Brugia malayi	Serotonin receptor	0.0042	0.0918	0.0918
Schistosoma mansoni	amine GPCR	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Mycobacterium ulcerans	glutamine-binding lipoprotein GlnH	0.002	0.0015	0.5
Schistosoma mansoni	opsin-like receptor	0.0042	0.0918	0.1552
Onchocerca volvulus		0.0042	0.0918	0.1552
Schistosoma mansoni	intermediate filament proteins	0.0026	0.0286	0.0484
Echinococcus multilocularis	orexin receptor type 2	0.0042	0.0918	0.1552
Echinococcus granulosus	dro:myosuppressin receptor	0.0042	0.0918	0.1552
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0042	0.0918	0.1552
Echinococcus multilocularis	serotonin receptor	0.0042	0.0918	0.1552
Chlamydia trachomatis	glutamine binding protein	0.002	0.0015	0.5
Echinococcus multilocularis	g-protein coupled receptor	0.0042	0.0918	0.1552
Echinococcus granulosus	g protein coupled receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Schistosoma mansoni	neuropeptide f receptor 76f	0.0042	0.0918	0.1552
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Plasmodium falciparum	ataxin-2 like protein, putative	0.0025	0.0217	1
Brugia malayi	hypothetical protein	0.0042	0.0918	0.0918
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Schistosoma mansoni	neuropeptide receptor	0.0042	0.0918	0.1552
Echinococcus multilocularis	neuropeptide receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	neuropeptide F receptor	0.0042	0.0918	0.0918
Echinococcus granulosus	g protein coupled receptor	0.0042	0.0918	0.1552
Onchocerca volvulus		0.0026	0.0286	0.0484
Echinococcus granulosus	tm gpcr rhodopsin	0.0042	0.0918	0.1552
Treponema pallidum	amino acid ABC transporter, periplasmic binding protein	0.002	0.0015	0.5
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0042	0.0918	0.0918
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0042	0.0918	0.1552
Echinococcus multilocularis	lamin dm0	0.0026	0.0286	0.0484
Schistosoma mansoni	biogenic amine receptor	0.0042	0.0918	0.1552
Echinococcus granulosus	g protein coupled receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus multilocularis	sex peptide receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus granulosus	somatostatin receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.0918	0.1552
Brugia malayi	RE15519p	0.0042	0.0918	0.0918
Brugia malayi	hypothetical protein	0.0042	0.0918	0.0918
Chlamydia trachomatis	arginine ABC transporter substrate-binding protein ArtJ	0.002	0.0015	0.5
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0042	0.0918	0.0918
Echinococcus multilocularis	fmrfamide receptor	0.0042	0.0918	0.1552
Echinococcus multilocularis	nmda type glutamate receptor	0.0108	0.3614	0.6113
Brugia malayi	neuropeptide F receptor	0.0042	0.0918	0.0918
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0042	0.0918	0.1552
Onchocerca volvulus		0.0042	0.0918	0.1552
Trichomonas vaginalis	glucosylceramidase, putative	0.0252	0.9418	1
Echinococcus granulosus	allatostatin A receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Brugia malayi	G-protein coupled receptor	0.0042	0.0918	0.0918
Echinococcus granulosus	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0042	0.0918	0.0918
Schistosoma mansoni	amine GPCR	0.0042	0.0918	0.1552
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0042	0.0918	0.1552
Treponema pallidum	amino acid ABC transporter, periplasmic binding protein (hisJ)	0.002	0.0015	0.5
Echinococcus granulosus	neuropeptide Y receptor	0.0042	0.0918	0.1552
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0042	0.0918	0.1552
Trypanosoma brucei	PAB1-binding protein , putative	0.0025	0.0217	0.5
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus multilocularis	musashi	0.0026	0.0286	0.0484
Echinococcus granulosus	neuropeptides capa receptor	0.0042	0.0918	0.1552
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0042	0.0918	0.0918
Onchocerca volvulus		0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Brugia malayi	G-protein coupled receptor	0.0042	0.0918	0.0918
Trypanosoma cruzi	PAB1-binding protein , putative	0.0025	0.0217	0.5
Onchocerca volvulus		0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0042	0.0918	0.1552
Echinococcus multilocularis	neuropeptide s receptor	0.0042	0.0918	0.1552
Onchocerca volvulus	Glucosylceramidase homolog	0.0165	0.5912	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus granulosus	serotonin receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Schistosoma mansoni	hypothetical protein	0.0042	0.0918	0.1552
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.0918	0.1552
Brugia malayi	hypothetical protein	0.0042	0.0918	0.0918
Brugia malayi	hypothetical protein	0.0042	0.0918	0.0918
Schistosoma mansoni	adenoreceptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	intermediate filament protein	0.0026	0.0286	0.0286
Echinococcus granulosus	neuropeptide receptor A26	0.0042	0.0918	0.1552
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	neuropeptide F-like receptor	0.0042	0.0918	0.1552
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0042	0.0918	0.1552
Echinococcus multilocularis	neuropeptide Y receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Brugia malayi	Melatonin receptor type 1A	0.0042	0.0918	0.0918
Echinococcus multilocularis	G protein coupled receptor 139	0.0042	0.0918	0.1552
Echinococcus multilocularis	neuropeptide Y receptor	0.0042	0.0918	0.1552
Echinococcus multilocularis	glutamate receptor NMDA	0.0081	0.2511	0.4247
Plasmodium vivax	ataxin-2 like protein, putative	0.0025	0.0217	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Schistosoma mansoni	opsin-like receptor	0.0042	0.0918	0.1552
Brugia malayi	neuropeptide F receptor	0.0042	0.0918	0.0918
Trichomonas vaginalis	glucosylceramidase, putative	0.0174	0.6272	0.1027
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0042	0.0918	0.1552
Schistosoma mansoni	lipoxygenase	0.0054	0.1401	0.237
Echinococcus granulosus	neuropeptides capa receptor	0.0042	0.0918	0.1552
Echinococcus multilocularis	fmrfamide receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Onchocerca volvulus		0.0042	0.0918	0.1552
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0042	0.0918	0.0918
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	lamin	0.0026	0.0286	0.0484
Echinococcus granulosus	tm gpcr rhodopsin	0.0042	0.0918	0.1552
Echinococcus granulosus	g-protein coupled receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.0918	0.1552
Echinococcus multilocularis	neuropeptides capa receptor	0.0042	0.0918	0.1552
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Schistosoma mansoni	histamine h1 receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	neuropeptide receptor	0.0042	0.0918	0.1552
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0266	1	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Brugia malayi	O-Glycosyl hydrolase family 30 protein	0.0252	0.9418	0.9418
Echinococcus multilocularis	lamin	0.0026	0.0286	0.0484
Echinococcus granulosus	biogenic amine 5HT receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	neuropeptide F-like receptor	0.0042	0.0918	0.1552
Mycobacterium tuberculosis	Probable glutamine-binding lipoprotein GlnH (GLNBP)	0.002	0.0015	0.5
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Brugia malayi	sulfakinin receptor protein	0.0042	0.0918	0.0918
Onchocerca volvulus		0.0042	0.0918	0.1552
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0042	0.0918	0.0918
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0042	0.0918	0.1552
Echinococcus multilocularis	g protein coupled receptor	0.0042	0.0918	0.1552
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0042	0.0918	0.1552
Brugia malayi	hypothetical protein	0.0042	0.0918	0.0918
Schistosoma mansoni	glutamate receptor NMDA	0.0093	0.2979	0.5039
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0042	0.0918	0.1552
Loa Loa (eye worm)	TYRA-2 protein	0.0042	0.0918	0.0918
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Schistosoma mansoni	hypothetical protein	0.0042	0.0918	0.1552
Brugia malayi	hypothetical protein	0.0042	0.0918	0.0918
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0042	0.0918	0.0918
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Brugia malayi	Dopamine receptor protein 1	0.0042	0.0918	0.0918
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0042	0.0918	0.1552
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Onchocerca volvulus		0.0042	0.0918	0.1552
Onchocerca volvulus		0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus granulosus	hypothetical protein	0.0042	0.0918	0.1552
Onchocerca volvulus		0.0042	0.0918	0.1552
Echinococcus granulosus	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus multilocularis	allatostatin A receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0026	0.0286	0.0286
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0042	0.0918	0.1552
Brugia malayi	hypothetical protein	0.0042	0.0918	0.0918
Brugia malayi	larval opioid receptor	0.0042	0.0918	0.0918
Schistosoma mansoni	opsin-like receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	G-protein coupled receptor	0.0042	0.0918	0.0918
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0042	0.0918	0.1552
Echinococcus granulosus	sex peptide receptor	0.0042	0.0918	0.1552
Plasmodium falciparum	ataxin-2 like protein, putative	0.0025	0.0217	1
Brugia malayi	intermediate filament protein	0.0026	0.0286	0.0286
Echinococcus granulosus	neuropeptide FF receptor 2	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0042	0.0918	0.1552
Brugia malayi	ORL1-like opioid receptor	0.0042	0.0918	0.0918
Echinococcus granulosus	neuropeptide Y receptor	0.0042	0.0918	0.1552
Onchocerca volvulus		0.0042	0.0918	0.1552
Brugia malayi	hypothetical protein	0.0042	0.0918	0.0918
Schistosoma mansoni	biogenic amine receptor	0.0042	0.0918	0.1552
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus granulosus	intermediate filament protein	0.0026	0.0286	0.0484
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Schistosoma mansoni	hypothetical protein	0.0165	0.5912	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Onchocerca volvulus		0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0042	0.0918	0.1552
Schistosoma mansoni	growth hormone secretagogue receptor	0.0042	0.0918	0.1552
Brugia malayi	Serotonin receptor	0.0042	0.0918	0.0918
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.0918	0.1552
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0042	0.0918	0.1552
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0042	0.0918	0.1552
Echinococcus granulosus	7TM GPCR rhodopsin	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Trichomonas vaginalis	glucosylceramidase, putative	0.0174	0.6272	0.1027
Schistosoma mansoni	biogenic amine receptor	0.0042	0.0918	0.1552
Echinococcus granulosus	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Schistosoma mansoni	amine GPCR	0.0042	0.0918	0.1552
Echinococcus granulosus	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Brugia malayi	G protein-coupled receptor F59B2.13	0.0042	0.0918	0.0918
Brugia malayi	hypothetical protein	0.0025	0.0217	0.0217
Loa Loa (eye worm)	O-glycosyl hydrolase family 30 protein	0.0252	0.9418	0.9418
Echinococcus multilocularis	somatostatin receptor	0.0042	0.0918	0.1552
Onchocerca volvulus		0.0042	0.0918	0.1552
Echinococcus granulosus	lamin dm0	0.0026	0.0286	0.0484
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0217	0.0217
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0042	0.0918	0.1552
Echinococcus multilocularis	dro:myosuppressin receptor	0.0042	0.0918	0.1552
Trichomonas vaginalis	glucosylceramidase, putative	0.0252	0.9418	1
Schistosoma mansoni	neuropeptide receptor	0.0042	0.0918	0.1552
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0042	0.0918	0.1552
Echinococcus granulosus	fmrfamide receptor	0.0042	0.0918	0.1552
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0042	0.0918	0.1552
Echinococcus granulosus	lamin	0.0026	0.0286	0.0484
Echinococcus multilocularis	g protein coupled receptor	0.0042	0.0918	0.1552
Echinococcus granulosus	neuropeptide receptor	0.0042	0.0918	0.1552
Echinococcus granulosus	G protein coupled receptor 139	0.0042	0.0918	0.1552
Echinococcus granulosus	glutamate receptor NMDA	0.0081	0.2511	0.4247
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Trichomonas vaginalis	glucosylceramidase, putative	0.0252	0.9418	1
Brugia malayi	Intermediate filament tail domain containing protein	0.0026	0.0286	0.0286
Onchocerca volvulus		0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus multilocularis	neuropeptide receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	G-protein coupled receptor	0.0042	0.0918	0.0918
Brugia malayi	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus multilocularis	serotonin receptor	0.0042	0.0918	0.1552
Echinococcus granulosus	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.0918	0.1552
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0042	0.0918	0.0918
Schistosoma mansoni	amine GPCR	0.0042	0.0918	0.1552
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Echinococcus granulosus	neuropeptide receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	melatonin receptor type 1A	0.0042	0.0918	0.0918
Toxoplasma gondii	LsmAD domain-containing protein	0.0025	0.0217	0.5
Echinococcus granulosus	nmda type glutamate receptor	0.0108	0.3614	0.6113
Brugia malayi	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0042	0.0918	0.1552
Brugia malayi	putative neuropeptide receptor NPR1	0.0042	0.0918	0.0918
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0042	0.0918	0.1552
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Brugia malayi	Dopamine receptor	0.0042	0.0918	0.0918
Schistosoma mansoni	lamin	0.0026	0.0286	0.0484
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0042	0.0918	0.1552
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0042	0.0918	0.1552
Onchocerca volvulus		0.0042	0.0918	0.1552
Trypanosoma cruzi	PAB1-binding protein , putative	0.0025	0.0217	0.5
Echinococcus granulosus	orexin receptor type 2	0.0042	0.0918	0.1552
Schistosoma mansoni	amine GPCR	0.0042	0.0918	0.1552
Echinococcus granulosus	geminin	0.0165	0.5912	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Echinococcus multilocularis	nmda type glutamate receptor	0.0085	0.2669	0.4515
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0042	0.0918	0.0918
Echinococcus multilocularis	neuropeptide receptor A26	0.0042	0.0918	0.1552
Onchocerca volvulus		0.0026	0.0286	0.0484
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Schistosoma mansoni	hypothetical protein	0.0042	0.0918	0.1552
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0042	0.0918	0.1552
Echinococcus multilocularis	neuropeptides capa receptor	0.0042	0.0918	0.1552
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0042	0.0918	0.0918
Schistosoma mansoni	neuropeptide receptor	0.0042	0.0918	0.1552
Schistosoma mansoni	hypothetical protein	0.0042	0.0918	0.1552
Echinococcus granulosus	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Brugia malayi	G protein-coupled receptor	0.0042	0.0918	0.0918
Onchocerca volvulus		0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0286	0.0286
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0918	0.0918
Trichomonas vaginalis	glucosylceramidase, putative	0.0252	0.9418	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.0918	0.1552
Schistosoma mansoni	hypothetical protein	0.0165	0.5912	1
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0042	0.0918	0.1552
Echinococcus granulosus	rhodopsin orphan GPCR	0.0042	0.0918	0.1552
Loa Loa (eye worm)	neuropeptide F receptor	0.0042	0.0918	0.0918
Brugia malayi	GnHR receptor homolog	0.0042	0.0918	0.0918
Onchocerca volvulus		0.0042	0.0918	0.1552
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0267	0.0267
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0042	0.0918	0.1552
Echinococcus granulosus	biogenic amine 5HT receptor	0.0042	0.0918	0.1552

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL3125838

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1827086