Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | membrane bound acyltransferase:hhat | 0.0557 | 0.0696 | 0.0693 |
Leishmania major | glycerol uptake protein, putative | 0.0557 | 0.0696 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0557 | 0.0696 | 0.0696 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0557 | 0.0696 | 0.0693 |
Loa Loa (eye worm) | diacylglycerol acyltransferase | 0.0557 | 0.0696 | 0.0696 |
Echinococcus granulosus | protein cysteine N palmitoyltransferase | 0.6468 | 1 | 1 |
Toxoplasma gondii | acyl-CoA:diacylglycerol acyltransferase 1-related enzyme | 0.0557 | 0.0696 | 0.5 |
Brugia malayi | Hhat protein | 0.0557 | 0.0696 | 0.0696 |
Echinococcus granulosus | zinc finger protein | 0.591 | 0.9123 | 0.9122 |
Brugia malayi | MBOAT family protein | 0.0557 | 0.0696 | 0.0696 |
Loa Loa (eye worm) | MBOAT family protein | 0.0557 | 0.0696 | 0.0696 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0557 | 0.0696 | 0.0641 |
Loa Loa (eye worm) | MBOAT family protein | 0.0557 | 0.0696 | 0.0696 |
Trichomonas vaginalis | porcupine, putative | 0.0557 | 0.0696 | 0.5 |
Echinococcus granulosus | diacylglycerol O acyltransferase 1 | 0.0557 | 0.0696 | 0.0693 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0557 | 0.0696 | 0.5 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0557 | 0.0696 | 0.0693 |
Echinococcus multilocularis | Membrane bound O acyl transferase, MBOAT | 0.0557 | 0.0696 | 0.0693 |
Schistosoma mansoni | zinc finger protein | 0.6468 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0557 | 0.0696 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0557 | 0.0696 | 0.5 |
Echinococcus multilocularis | protein cysteine N palmitoyltransferase | 0.6468 | 1 | 1 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0557 | 0.0696 | 0.0693 |
Plasmodium vivax | diacylglycerol O-acyltransferase, putative | 0.0557 | 0.0696 | 0.5 |
Echinococcus granulosus | integrin beta 2 | 0.0232 | 0.0183 | 0.018 |
Loa Loa (eye worm) | hypothetical protein | 0.0557 | 0.0696 | 0.0696 |
Brugia malayi | MBOAT family protein | 0.0557 | 0.0696 | 0.0696 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0557 | 0.0696 | 0.0641 |
Leishmania major | glycerol uptake protein, putative | 0.0557 | 0.0696 | 0.5 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0557 | 0.0696 | 0.5 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0557 | 0.0696 | 0.5 |
Trichomonas vaginalis | transmembrane protein nessy, putative | 0.0557 | 0.0696 | 0.5 |
Echinococcus multilocularis | diacylglycerol O acyltransferase 1 | 0.0557 | 0.0696 | 0.0693 |
Trypanosoma cruzi | GUP1, putative | 0.0557 | 0.0696 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0557 | 0.0696 | 0.5 |
Echinococcus multilocularis | membrane bound acyltransferase:hhat | 0.0557 | 0.0696 | 0.0693 |
Loa Loa (eye worm) | integrin alpha pat-2 | 0.0235 | 0.0189 | 0.0189 |
Treponema pallidum | alginate O-acetylation protein (algI) | 0.0557 | 0.0696 | 0.5 |
Entamoeba histolytica | vacuolar protein sorting 26 | 0.0557 | 0.0696 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0557 | 0.0696 | 0.5 |
Loa Loa (eye worm) | hhat protein | 0.0557 | 0.0696 | 0.0696 |
Brugia malayi | Integrin beta pat-3 precursor | 0.0313 | 0.031 | 0.031 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0557 | 0.0696 | 0.5 |
Leishmania major | glycerol uptake protein, putative | 0.0557 | 0.0696 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0557 | 0.0696 | 0.0696 |
Loa Loa (eye worm) | MBOAT family protein | 0.6468 | 1 | 1 |
Trypanosoma cruzi | GUP1, putative | 0.0557 | 0.0696 | 0.5 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0557 | 0.0696 | 0.0693 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | hhat protein | 0.0557 | 0.0696 | 0.0696 |
Echinococcus granulosus | sterol O acyltransferase 1 | 0.0557 | 0.0696 | 0.0693 |
Loa Loa (eye worm) | integrin beta-2 | 0.0313 | 0.031 | 0.031 |
Trypanosoma brucei | glycerol uptake protein, putative | 0.0557 | 0.0696 | 0.5 |
Echinococcus multilocularis | lysophospholipid acyltransferase 7 | 0.0557 | 0.0696 | 0.0693 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0557 | 0.0696 | 0.5 |
Schistosoma mansoni | leukocyte receptor cluster (lrc) member 4 protein | 0.0557 | 0.0696 | 0.0641 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0557 | 0.0696 | 0.5 |
Loa Loa (eye worm) | membrane bound O-acyltransferase domain containing 1 | 0.0557 | 0.0696 | 0.0696 |
Schistosoma mansoni | sterol O-acyltransferase 1 | 0.0557 | 0.0696 | 0.0641 |
Brugia malayi | MBOAT family protein | 0.0557 | 0.0696 | 0.0696 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0557 | 0.0696 | 0.5 |
Brugia malayi | diacylglycerol acyltransferase | 0.0557 | 0.0696 | 0.0696 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0557 | 0.0696 | 0.5 |
Schistosoma mansoni | membrane-bound acyltransferase/hhat | 0.0557 | 0.0696 | 0.0641 |
Brugia malayi | MBOAT family protein | 0.0557 | 0.0696 | 0.0696 |
Schistosoma mansoni | diacylglycerol O-acyltransferase 1 | 0.0557 | 0.0696 | 0.0641 |
Onchocerca volvulus | 0.0557 | 0.0696 | 0.5 | |
Leishmania major | glycerol uptake protein, putative | 0.0557 | 0.0696 | 0.5 |
Brugia malayi | Integrin alpha pat-2 precursor | 0.0153 | 0.0059 | 0.0059 |
Echinococcus multilocularis | zinc finger protein | 0.591 | 0.9123 | 0.9122 |
Echinococcus multilocularis | integrin beta 2 | 0.0232 | 0.0183 | 0.018 |
Entamoeba histolytica | hypothetical protein | 0.0557 | 0.0696 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0557 | 0.0696 | 0.0696 |
Trypanosoma brucei | glycerol uptake protein, putative | 0.0557 | 0.0696 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0557 | 0.0696 | 0.0641 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0557 | 0.0696 | 0.0693 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0557 | 0.0696 | 0.0641 |
Echinococcus multilocularis | sterol O acyltransferase 1 | 0.0557 | 0.0696 | 0.0693 |
Echinococcus granulosus | Membrane bound O acyl transferase MBOAT | 0.0557 | 0.0696 | 0.0693 |
Plasmodium falciparum | diacylglycerol O-acyltransferase | 0.0557 | 0.0696 | 0.5 |
Echinococcus granulosus | lysophospholipid acyltransferase 7 | 0.0557 | 0.0696 | 0.0693 |
Toxoplasma gondii | acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha | 0.0557 | 0.0696 | 0.5 |
Leishmania major | glycerol uptake protein, putative | 0.0557 | 0.0696 | 0.5 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0557 | 0.0696 | 0.0693 |
Schistosoma mansoni | integrin beta subunit | 0.0184 | 0.0108 | 0.005 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.