TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 498.844 | Formula: C19H17BrClN3O2S2
H donors: 0 H acceptors: 3 LogP: 5.89 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: Brc1ccc(cc1)CN1C(=O)S/C(=C\c2sc(nc2Cl)N2CCCCC2)/C1=O
InChi: 1S/C19H17BrClN3O2S2/c20-13-6-4-12(5-7-13)11-24-17(25)15(28-19(24)26)10-14-16(21)22-18(27-14)23-8-2-1-3-9-23/h4-7,10H,1-3,8-9,11H2/b15-10-
InChiKey: ZLXNOCUOJWJHOP-GDNBJRDFSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Giardia lamblia	DINP protein human, muc B family	0.0032	0.0079	1
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0029	0.006	0.006
Plasmodium vivax	SET domain protein, putative	0.0023	0.0028	0.2745
Schistosoma mansoni	ubiquitin-specific peptidase 8 (C19 family)	0.0026	0.0045	0.0045
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0048	0.0171	0.0171
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0048	0.0171	0.0171
Brugia malayi	6-phosphofructokinase	0.0103	0.0498	0.0498
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0082	0.0372	0.4191
Schistosoma mansoni	hypothetical protein	0.0029	0.006	0.006
Schistosoma mansoni	hypothetical protein	0.0029	0.006	0.006
Plasmodium falciparum	ATP-dependent 6-phosphofructokinase	0.0028	0.0054	0.5328
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.0079	0.0376
Trypanosoma cruzi	DNA polymerase eta, putative	0.0052	0.0198	0.0996
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	0.0036	0.0101	0.0324
Loa Loa (eye worm)	3-hydroxyacyl-CoA dehydrogenase type II	0.0051	0.0189	0.0189
Schistosoma mansoni	hypothetical protein	0.0029	0.006	0.006
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.0032	0.0079	0.0079
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0082	0.0372	0.4191
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0048	0.0171	0.0171
Mycobacterium tuberculosis	Probable dehydrogenase	0.0082	0.0372	0.4191
Mycobacterium ulcerans	6-phosphofructokinase	0.0103	0.0498	0.598
Trypanosoma cruzi	mitochondrial DNA polymerase beta, putative	0.0286	0.1579	1
Schistosoma mansoni	terminal deoxycytidyl transferase	0.0032	0.0079	0.0079
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.0091	0.0426	0.496
Entamoeba histolytica	phosphofructokinase, putative	0.0103	0.0498	1
Loa Loa (eye worm)	6-phosphofructokinase	0.0103	0.0498	0.0498
Loa Loa (eye worm)	phosphofructokinase	0.0103	0.0498	0.0498
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0028	0.0028
Trypanosoma cruzi	ATP-dependent 6-phosphofructokinase, glycosomal	0.0103	0.0498	0.2952
Echinococcus multilocularis	alpha 1,6 mannosyl glycoprotein	0.171	1	1
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0023	0.0028	0.0028
Leishmania major	DNA polymerase kappa, putative	0.0032	0.0079	0.022
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0082	0.0372	0.4191
Brugia malayi	follicle stimulating hormone receptor	0.0221	0.1196	0.1196
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0048	0.0171	0.0171
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0029	0.006	0.006
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0029	0.006	0.006
Brugia malayi	phosphofructokinase	0.0103	0.0498	0.0498
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	0.0054	0.0211	0.1884
Echinococcus multilocularis	neuropeptide receptor A26	0.0363	0.2038	0.2038
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0036	0.0104	0.0104
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0023	0.0028	0.0028
Trichomonas vaginalis	phosphofructokinase, putative	0.0028	0.0054	0.0098
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0026	0.0045	0.0045
Toxoplasma gondii	ImpB/MucB/SamB family protein	0.0052	0.0198	1
Echinococcus granulosus	dna polymerase kappa	0.0032	0.0079	0.0079
Brugia malayi	glutathione reductase	0.0036	0.0101	0.0101
Loa Loa (eye worm)	glutathione reductase	0.0036	0.0101	0.0101
Trypanosoma brucei	DNA polymerase IV, putative	0.0032	0.0079	0.0376
Trypanosoma cruzi	DNA polymerase beta thumb, putative	0.004	0.0127	0.0538
Echinococcus multilocularis	GPCR, family 2	0.0029	0.006	0.006
Schistosoma mansoni	3-hydroxyacyl-CoA dehydrogenase	0.0054	0.0211	0.0211
Toxoplasma gondii	phosphofructokinase domain-containing protein	0.0028	0.0054	0.1541
Mycobacterium tuberculosis	Probable reductase	0.0082	0.0372	0.4191
Trypanosoma brucei	DNA polymerase beta thumb, putative	0.004	0.0127	0.0688
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0029	0.006	0.006
Onchocerca volvulus		0.0023	0.0028	0.0282
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 8	0.0026	0.0045	0.0045
Plasmodium vivax	6-phosphofructokinase, putative	0.0028	0.0054	0.5328
Plasmodium vivax	thioredoxin reductase, putative	0.0036	0.0101	1
Brugia malayi	Latrophilin receptor protein 2	0.0029	0.006	0.006
Trypanosoma cruzi	trypanothione reductase, putative	0.0036	0.0101	0.0369
Schistosoma mansoni	hypothetical protein	0.0176	0.0933	0.0933
Trichomonas vaginalis	6-phosphofructokinase, putative	0.0028	0.0054	0.0098
Echinococcus granulosus	Peptidase C19 ubiquitin carboxyl terminal hydrolase 2	0.0026	0.0045	0.0045
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0091	0.0427	0.0427
Mycobacterium tuberculosis	Probable oxidoreductase	0.0091	0.0426	0.496
Trichomonas vaginalis	set domain proteins, putative	0.0185	0.0986	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.0079	0.0376
Toxoplasma gondii	hypothetical protein	0.0046	0.0162	0.7914
Trichomonas vaginalis	phosphofructokinase, putative	0.0103	0.0498	0.4815
Echinococcus multilocularis	neuropeptide s receptor	0.0363	0.2038	0.2038
Echinococcus granulosus	3 hydroxyacyl coenzyme A dehydrogenase type 2	0.0054	0.0211	0.0211
Mycobacterium tuberculosis	Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase)	0.0103	0.0498	0.598
Echinococcus multilocularis	3 hydroxyacyl coenzyme A dehydrogenase type 2	0.0054	0.0211	0.0211
Toxoplasma gondii	thioredoxin reductase	0.0036	0.0101	0.4329
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.0049	0.0179	0.0877
Echinococcus multilocularis	Peptidase C19, ubiquitin carboxyl terminal hydrolase 2	0.0026	0.0045	0.0045
Leishmania major	trypanothione reductase	0.0036	0.0101	0.0369
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0427	0.0427
Entamoeba histolytica	pyrophosphate-dependent phosphofructokinase	0.0028	0.0054	0.0204
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0032	0.0079	0.022
Leishmania major	DNA polymerase eta, putative	0.0052	0.0198	0.0996
Trichomonas vaginalis	phosphofructokinase, putative	0.0028	0.0054	0.0098
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0221	0.1196	0.1196
Trichomonas vaginalis	phosphofructokinase, putative	0.0028	0.0054	0.0098
Loa Loa (eye worm)	6-phosphofructokinase	0.0103	0.0498	0.0498
Leishmania major	mitochondrial DNA polymerase beta	0.0286	0.1579	1
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0091	0.0427	0.0427
Trichomonas vaginalis	DNA polymerase eta, putative	0.0032	0.0079	0.036
Brugia malayi	ImpB/MucB/SamB family protein	0.0074	0.0328	0.0328
Brugia malayi	3-hydroxyacyl-CoA dehydrogenase type II	0.0054	0.0211	0.0211
Schistosoma mansoni	hypothetical protein	0.0062	0.0257	0.0257
Schistosoma mansoni	6-phosphofructokinase	0.0103	0.0498	0.0498
Schistosoma mansoni	DNA polymerase eta	0.0074	0.0328	0.0328
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0257	0.0257
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0048	0.0171	0.0171
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0023	0.0028	0.0028
Loa Loa (eye worm)	thioredoxin reductase	0.0036	0.0101	0.0101
Echinococcus multilocularis	ubiquitin specific protease 41	0.0026	0.0045	0.0045
Echinococcus multilocularis	6 phosphofructokinase	0.0103	0.0498	0.0498
Loa Loa (eye worm)	hypothetical protein	0.171	1	1
Leishmania major	3-oxoacyl-(acyl-carrier protein) reductase, putative	0.0054	0.0211	0.1081
Mycobacterium tuberculosis	Conserved hypothetical protein	0.015	0.078	1
Trypanosoma brucei	unspecified product	0.0032	0.0079	0.0376
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.0079	0.0376
Trichomonas vaginalis	phosphofructokinase, putative	0.0103	0.0498	0.4815
Toxoplasma gondii	6-phosphofructokinase	0.0028	0.0054	0.1541
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0023	0.0028	0.0028
Chlamydia trachomatis	fructose-6-phosphate phosphotransferase	0.0028	0.0054	0.5
Echinococcus multilocularis	dna polymerase kappa	0.0032	0.0079	0.0079
Trypanosoma brucei	DNA polymerase eta, putative	0.0074	0.0328	0.1975
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0045	0.0045
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0029	0.006	0.006
Echinococcus granulosus	geminin	0.0176	0.0933	0.0933
Plasmodium falciparum	thioredoxin reductase	0.0036	0.0101	1
Brugia malayi	ImpB/MucB/SamB family protein	0.0032	0.0079	0.0079
Trichomonas vaginalis	phosphofructokinase, putative	0.0103	0.0498	0.4815
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.0079	0.0376
Echinococcus multilocularis	arachidonate 5 lipoxygenase	0.0052	0.0199	0.0199
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0048	0.0171	0.0171
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.0079	0.0376
Schistosoma mansoni	6-phosphofructokinase	0.0103	0.0498	0.0498
Trypanosoma cruzi	mitochondrial DNA polymerase beta, putative	0.0286	0.1579	1
Schistosoma mansoni	hypothetical protein	0.0176	0.0933	0.0933
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0091	0.0427	0.0427
Echinococcus granulosus	arachidonate 5 lipoxygenase	0.0052	0.0199	0.0199
Entamoeba histolytica	phosphofructokinase, putative	0.0103	0.0498	1
Brugia malayi	Pre-SET motif family protein	0.0023	0.0028	0.0028
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0048	0.0171	0.0171
Trichomonas vaginalis	phosphofructokinase, putative	0.0028	0.0054	0.0098
Leishmania major	ATP-dependent phosphofructokinase	0.0103	0.0498	0.2952
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.0079	0.0376
Plasmodium falciparum	ATP-dependent 6-phosphofructokinase	0.0028	0.0054	0.5328
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0054	0.0211	0.1884
Trypanosoma brucei	mitochondrial DNA polymerase beta-PAK	0.0135	0.0689	0.4293
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0328	0.0328
Echinococcus granulosus	dna polymerase eta	0.0074	0.0328	0.0328
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.0135	0.0689	0.4201
Trichomonas vaginalis	phosphofructokinase, putative	0.0103	0.0498	0.4815
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0032	0.0079	0.022
Trypanosoma cruzi	DNA polymerase eta, putative	0.0074	0.0328	0.1845
Toxoplasma gondii	phosphofructokinase PFKII	0.0028	0.0054	0.1541
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0082	0.0372	0.4191
Brugia malayi	Pre-SET motif family protein	0.0163	0.0853	0.0853
Trypanosoma brucei	DNA polymerase IV, putative	0.0032	0.0079	0.0376
Leishmania major	DNA polymerase kappa, putative,DNA polymerase IV, putative	0.0032	0.0079	0.022
Echinococcus granulosus	ubiquitin specific protease 41	0.0026	0.0045	0.0045
Leishmania major	DNA polymerase eta, putative	0.0074	0.0328	0.1845
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0048	0.0171	0.0171
Trypanosoma brucei	DNA polymerase IV, putative	0.0032	0.0079	0.0376
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0054	0.0211	0.1884
Trichomonas vaginalis	phosphofructokinase, putative	0.0028	0.0054	0.0098
Echinococcus granulosus	GPCR family 2	0.0029	0.006	0.006
Onchocerca volvulus		0.0185	0.0986	1
Loa Loa (eye worm)	hypothetical protein	0.0029	0.006	0.006
Trypanosoma brucei	trypanothione reductase	0.0036	0.0101	0.0522
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0022	0.0023	0.0023
Trichomonas vaginalis	phosphofructokinase, putative	0.0028	0.0054	0.0098
Echinococcus granulosus	6 phosphofructokinase	0.0103	0.0498	0.0498
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0029	0.006	0.006
Echinococcus granulosus	neuropeptide receptor A26	0.0363	0.2038	0.2038
Giardia lamblia	Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit	0.0028	0.0054	0.2733
Schistosoma mansoni	lipoxygenase	0.0052	0.0199	0.0199
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.0079	0.0376
Mycobacterium leprae	PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE)	0.0103	0.0498	1
Entamoeba histolytica	phosphofructokinase, putative	0.0103	0.0498	1
Echinococcus multilocularis	geminin	0.0176	0.0933	0.0933
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0048	0.0171	0.0171
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0091	0.0426	0.4297
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.0032	0.0079	0.036
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0023	0.0028	0.0028
Schistosoma mansoni	ubiquitin-specific peptidase 2 (C19 family)	0.0026	0.0045	0.0045
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0032	0.0079	0.022
Chlamydia trachomatis	fructose-6-phosphate phosphotransferase	0.0028	0.0054	0.5
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.004	0.0127	0.0538
Leishmania major	mitochondrial DNA polymerase beta-PAK, putative	0.0135	0.0689	0.4201
Echinococcus multilocularis	dna polymerase eta	0.0074	0.0328	0.0328
Brugia malayi	Thioredoxin reductase	0.0036	0.0101	0.0101
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0163	0.0853	0.0853
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 8	0.0026	0.0045	0.0045
Echinococcus granulosus	thioredoxin glutathione reductase	0.0036	0.0104	0.0104
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0023	0.0028	0.0028
Trypanosoma cruzi	DNA polymerase beta thumb, putative	0.004	0.0127	0.0538
Mycobacterium ulcerans	hypothetical protein	0.015	0.078	1
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.0032	0.0079	0.0079
Brugia malayi	6-phosphofructokinase	0.0103	0.0498	0.0498
Plasmodium falciparum	glutathione reductase	0.0036	0.0101	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.0079	0.0376
Echinococcus granulosus	histone lysine methyltransferase setb	0.0023	0.0028	0.0028
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.0091	0.0426	0.496
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.0032	0.0079	0.0079
Plasmodium vivax	glutathione reductase, putative	0.0036	0.0101	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.0079	0.0376
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.0079	0.0376
Brugia malayi	latrophilin 2 splice variant baaae	0.0062	0.0257	0.0257
Trypanosoma brucei	mitochondrial DNA polymerase beta	0.0286	0.1579	1
Entamoeba histolytica	deoxycytidyl transferase, putative	0.0032	0.0079	0.0747
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0026	0.0045	0.0159
Plasmodium vivax	6-phosphofructokinase, putative	0.0028	0.0054	0.5328
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.0032	0.0079	0.0079
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0032	0.0079	0.022
Trypanosoma brucei	ATP-dependent 6-phosphofructokinase, glycosomal	0.0103	0.0498	0.3064
Schistosoma mansoni	hypothetical protein	0.0029	0.006	0.006
Schistosoma mansoni	beta-12-n-acetylglucosaminyltransferase II	0.171	1	1
Echinococcus granulosus	alpha 16 mannosyl glycoprotein	0.171	1	1
Treponema pallidum	diphosphate--fructose-6-phosphate 1-phosphotransferase	0.0103	0.0498	1
Echinococcus granulosus	neuropeptide s receptor	0.0363	0.2038	0.2038

Activities

Activity type	Activity value	Assay description	Source	Reference
Inhibition (binding)	= 0.62 %	Inhibition of Rattus norvegicus (rat) kidney aldose reductase using D-L-glyceraldehyde as substRattus norvegicus (rat) e assessed as decrease in NADPH level at 10'-4 M measured for 5 min by spectrophotometric analysis	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2262693

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1842520