Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | zinc finger protein | 0.099 | 0.912 | 0.9108 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0217 | 0.009 |
Leishmania major | glycerol uptake protein, putative | 0.0093 | 0.0667 | 1 |
Trypanosoma cruzi | GUP1, putative | 0.0093 | 0.0667 | 1 |
Loa Loa (eye worm) | MBOAT family protein | 0.0093 | 0.0667 | 0.0667 |
Trypanosoma brucei | glycerol uptake protein, putative | 0.0093 | 0.0667 | 1 |
Trichomonas vaginalis | transmembrane protein nessy, putative | 0.0093 | 0.0667 | 1 |
Schistosoma mansoni | membrane-bound acyltransferase/hhat | 0.0093 | 0.0667 | 0.0546 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0093 | 0.0667 | 1 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0093 | 0.0667 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0093 | 0.0667 | 0.0546 |
Echinococcus granulosus | sterol O acyltransferase 1 | 0.0093 | 0.0667 | 0.0546 |
Treponema pallidum | alginate O-acetylation protein (algI) | 0.0093 | 0.0667 | 0.5 |
Plasmodium falciparum | diacylglycerol O-acyltransferase | 0.0093 | 0.0667 | 0.5 |
Toxoplasma gondii | acyl-CoA:diacylglycerol acyltransferase 1-related enzyme | 0.0093 | 0.0667 | 0.5 |
Brugia malayi | Hhat protein | 0.0093 | 0.0667 | 0.0667 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0093 | 0.0667 | 0.0546 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0217 | 0.009 |
Loa Loa (eye worm) | hhat protein | 0.0093 | 0.0667 | 0.0667 |
Echinococcus granulosus | Membrane bound O acyl transferase MBOAT | 0.0093 | 0.0667 | 0.0546 |
Loa Loa (eye worm) | MBOAT family protein | 0.0093 | 0.0667 | 0.0667 |
Echinococcus granulosus | diacylglycerol O acyltransferase 1 | 0.0093 | 0.0667 | 0.0546 |
Toxoplasma gondii | acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha | 0.0093 | 0.0667 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0667 | 0.0667 |
Leishmania major | glycerol uptake protein, putative | 0.0093 | 0.0667 | 1 |
Echinococcus granulosus | protein cysteine N palmitoyltransferase | 0.1083 | 1 | 1 |
Loa Loa (eye worm) | hhat protein | 0.0093 | 0.0667 | 0.0667 |
Echinococcus multilocularis | membrane bound acyltransferase:hhat | 0.0093 | 0.0667 | 0.0546 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0217 | 0.009 |
Plasmodium vivax | diacylglycerol O-acyltransferase, putative | 0.0093 | 0.0667 | 0.5 |
Trypanosoma cruzi | GUP1, putative | 0.0093 | 0.0667 | 1 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0093 | 0.0667 | 0.0546 |
Loa Loa (eye worm) | diacylglycerol acyltransferase | 0.0093 | 0.0667 | 0.0667 |
Trypanosoma brucei | glycerol uptake protein, putative | 0.0093 | 0.0667 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0093 | 0.0667 | 1 |
Echinococcus multilocularis | sterol O acyltransferase 1 | 0.0093 | 0.0667 | 0.0546 |
Echinococcus granulosus | lysophospholipid acyltransferase 7 | 0.0093 | 0.0667 | 0.0546 |
Schistosoma mansoni | sterol O-acyltransferase 1 | 0.0093 | 0.0667 | 0.0546 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0093 | 0.0667 | 0.0546 |
Leishmania major | glycerol uptake protein, putative | 0.0093 | 0.0667 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0217 | 0.009 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0093 | 0.0667 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0217 | 0.0217 |
Echinococcus granulosus | membrane bound acyltransferase:hhat | 0.0093 | 0.0667 | 0.0546 |
Loa Loa (eye worm) | MBOAT family protein | 0.1083 | 1 | 1 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0093 | 0.0667 | 1 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0297 | 0.2584 | 0.2488 |
Leishmania major | hypothetical protein, conserved | 0.0093 | 0.0667 | 1 |
Echinococcus multilocularis | protein cysteine N palmitoyltransferase | 0.1083 | 1 | 1 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0093 | 0.0667 | 1 |
Echinococcus multilocularis | Membrane bound O acyl transferase, MBOAT | 0.0093 | 0.0667 | 0.0546 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0093 | 0.0667 | 1 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0093 | 0.0667 | 1 |
Brugia malayi | MBOAT family protein | 0.0093 | 0.0667 | 0.0667 |
Leishmania major | glycerol uptake protein, putative | 0.0093 | 0.0667 | 1 |
Loa Loa (eye worm) | membrane bound O-acyltransferase domain containing 1 | 0.0093 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0667 | 0.0667 |
Echinococcus multilocularis | zinc finger protein | 0.099 | 0.912 | 0.9108 |
Onchocerca volvulus | 0.0093 | 0.0667 | 0.5 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0217 | 0.009 |
Trichomonas vaginalis | porcupine, putative | 0.0093 | 0.0667 | 1 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0036 | 0.0128 | 0.5 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0093 | 0.0667 | 0.0546 |
Schistosoma mansoni | zinc finger protein | 0.1083 | 1 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0093 | 0.0667 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0667 | 0.0667 |
Leishmania major | glycerol uptake protein, putative | 0.0093 | 0.0667 | 1 |
Schistosoma mansoni | leukocyte receptor cluster (lrc) member 4 protein | 0.0093 | 0.0667 | 0.0546 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0217 | 0.0217 |
Echinococcus multilocularis | lysophospholipid acyltransferase 7 | 0.0093 | 0.0667 | 0.0546 |
Brugia malayi | MBOAT family protein | 0.0093 | 0.0667 | 0.0667 |
Schistosoma mansoni | diacylglycerol O-acyltransferase 1 | 0.0093 | 0.0667 | 0.0546 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0093 | 0.0667 | 0.0546 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0093 | 0.0667 | 0.0546 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0036 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0667 | 0.0667 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0217 | 0.009 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0093 | 0.0667 | 1 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0093 | 0.0667 | 0.0546 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0093 | 0.0667 | 0.0546 |
Brugia malayi | MBOAT family protein | 0.0093 | 0.0667 | 0.0667 |
Brugia malayi | diacylglycerol acyltransferase | 0.0093 | 0.0667 | 0.0667 |
Entamoeba histolytica | vacuolar protein sorting 26 | 0.0093 | 0.0667 | 1 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0297 | 0.2584 | 0.2488 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0093 | 0.0667 | 1 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0093 | 0.0667 | 1 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0093 | 0.0667 | 0.0546 |
Brugia malayi | MBOAT family protein | 0.0093 | 0.0667 | 0.0667 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0217 | 0.009 |
Echinococcus multilocularis | diacylglycerol O acyltransferase 1 | 0.0093 | 0.0667 | 0.0546 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.