Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | serine peptidase, clan SC, family S9A-like protein | 0.0821 | 0.0701 | 0.1162 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0821 | 0.0701 | 1 |
Schistosoma mansoni | acylaminoacyl-peptidase (S09 family) | 0.0821 | 0.0701 | 0.0591 |
Toxoplasma gondii | prolyl endopeptidase | 0.0821 | 0.0701 | 0.1516 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0821 | 0.0701 | 0.0701 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.4436 | 0.5144 | 1 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.4436 | 0.5144 | 1 |
Chlamydia trachomatis | aminopeptidase P | 0.0448 | 0.0243 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0821 | 0.0701 | 1 |
Echinococcus granulosus | prolyl endopeptidase | 0.0821 | 0.0701 | 0.0591 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0821 | 0.0701 | 1 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0814 | 0.0693 | 0.0693 |
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.0821 | 0.0701 | 0.0591 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0821 | 0.0701 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0821 | 0.0701 | 0.0701 |
Trypanosoma brucei | Alpha/beta hydrolase domain-containing protein | 0.0821 | 0.0701 | 0.1162 |
Schistosoma mansoni | aminopeptidase P1 (M24 family) | 0.0409 | 0.0195 | 0.008 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.8387 | 1 | 1 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0821 | 0.0701 | 1 |
Mycobacterium tuberculosis | Probable peptidase | 0.0821 | 0.0701 | 1 |
Trypanosoma cruzi | oligopeptidase b | 0.0821 | 0.0701 | 0.1162 |
Echinococcus granulosus | acylamino acid releasing enzyme | 0.0821 | 0.0701 | 0.0591 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0821 | 0.0701 | 0.0591 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0821 | 0.0701 | 0.0701 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0821 | 0.0701 | 0.1162 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.4436 | 0.5144 | 1 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0821 | 0.0701 | 1 |
Entamoeba histolytica | aminopeptidase, putative | 0.0814 | 0.0693 | 0.9861 |
Trypanosoma brucei | prolyl oligopeptidase, putative | 0.0821 | 0.0701 | 0.1162 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0821 | 0.0701 | 0.0591 |
Echinococcus granulosus | xaa pro aminopeptidase | 0.0814 | 0.0693 | 0.0583 |
Onchocerca volvulus | 0.0448 | 0.0243 | 0.0127 | |
Echinococcus multilocularis | acylamino acid releasing enzyme | 0.0821 | 0.0701 | 0.0591 |
Trypanosoma cruzi | serine peptidase, clan SC, family S9A-like protein, putative | 0.0821 | 0.0701 | 0.1162 |
Loa Loa (eye worm) | hypothetical protein | 0.0821 | 0.0701 | 0.0591 |
Brugia malayi | prolyl oligopeptidase family protein | 0.4436 | 0.5144 | 0.5144 |
Loa Loa (eye worm) | hypothetical protein | 0.0593 | 0.0421 | 0.0307 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.4436 | 0.5144 | 0.5086 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0821 | 0.0701 | 1 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0814 | 0.0693 | 0.986 |
Leishmania major | aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 | 0.0814 | 0.0693 | 0.1146 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0821 | 0.0701 | 0.0591 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0821 | 0.0701 | 0.0591 |
Brugia malayi | hypothetical protein | 0.2661 | 0.2963 | 0.2963 |
Leishmania major | oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein | 0.0821 | 0.0701 | 0.1162 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.3482 | 0.3972 | 1 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.4436 | 0.5144 | 0.5086 |
Trypanosoma brucei | Xaa-Pro aminopeptidase, putative | 0.0814 | 0.0693 | 0.1146 |
Plasmodium vivax | hypothetical protein, conserved | 0.0821 | 0.0701 | 1 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.8387 | 1 | 1 |
Trypanosoma brucei | prolyl endopeptidase | 0.0821 | 0.0701 | 0.1162 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.4436 | 0.5144 | 0.5086 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.8387 | 1 | 1 |
Trypanosoma cruzi | aminopeptidase P1, putative | 0.0814 | 0.0693 | 0.1146 |
Plasmodium falciparum | peptidase, putative | 0.0821 | 0.0701 | 1 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.8387 | 1 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0821 | 0.0701 | 0.0591 |
Loa Loa (eye worm) | hypothetical protein | 0.0821 | 0.0701 | 0.0591 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0821 | 0.0701 | 1 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0345 | 0.0117 | 0.0117 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0821 | 0.0701 | 0.1162 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24, putative | 0.0814 | 0.0693 | 0.1146 |
Toxoplasma gondii | acylaminoacyl-peptidase, putative | 0.0821 | 0.0701 | 0.1516 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0821 | 0.0701 | 1 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.8387 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0821 | 0.0701 | 1 |
Trypanosoma cruzi | oligopeptidase B-like protein, putative | 0.0821 | 0.0701 | 0.1162 |
Treponema pallidum | aminopeptidase P | 0.0814 | 0.0693 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1774 | 0.1873 | 0.1777 |
Mycobacterium tuberculosis | Probable protease II PtrBb [second part] (oligopeptidase B) | 0.0821 | 0.0701 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.4436 | 0.5144 | 1 |
Leishmania major | oligopeptidase b | 0.0821 | 0.0701 | 0.1162 |
Wolbachia endosymbiont of Brugia malayi | Xaa-Pro aminopeptidase | 0.0814 | 0.0693 | 0.5 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0821 | 0.0701 | 1 |
Echinococcus multilocularis | xaa pro aminopeptidase | 0.0814 | 0.0693 | 0.0583 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0821 | 0.0701 | 1 |
Trypanosoma brucei | oligopeptidase b | 0.0821 | 0.0701 | 0.1162 |
Toxoplasma gondii | creatinase domain-containing protein | 0.0814 | 0.0693 | 0.1495 |
Trypanosoma cruzi | oligopeptidase b | 0.0821 | 0.0701 | 0.1162 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0821 | 0.0701 | 1 |
Leishmania major | aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 | 0.0593 | 0.0421 | 0.0605 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.0821 | 0.0701 | 0.1162 |
Toxoplasma gondii | hypothetical protein | 0.0821 | 0.0701 | 0.1516 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.4436 | 0.5144 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2661 | 0.2963 | 0.288 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0821 | 0.0701 | 0.1162 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.