TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 507.581 | Formula: C27H33N5O5
H donors: 2 H acceptors: 5 LogP: 2.31 Rotable bonds: 7
Rule of 5 violations (Lipinski): 2
SMILES: O=C(c1nnn(c1c1ccc(cc1)CN1CCOCC1)c1cc(C(C)C)c(cc1O)O)N1CCOCC1
InChi: 1S/C27H33N5O5/c1-18(2)21-15-22(24(34)16-23(21)33)32-26(25(28-29-32)27(35)31-9-13-37-14-10-31)20-5-3-19(4-6-20)17-30-7-11-36-12-8-30/h3-6,15-16,18,33-34H,7-14,17H2,1-2H3
InChiKey: GSUOVFJJGRKABZ-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	heat shock protein 90kDa alpha (cytosolic), class A member 1	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Leishmania braziliensis	lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma cruzi	heat shock protein 85, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Echinococcus multilocularis	heat shock protein 90	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma cruzi	heat shock protein 85, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Giardia lamblia	Heat shock protein HSP 90-alpha	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma cruzi	heat shock protein 90, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei gambiense	heat shock protein 83,heat shock protein	Get druggable targets OG5_126623	All targets in OG5_126623
Plasmodium yoelii	heat shock protein 90	Get druggable targets OG5_126623	All targets in OG5_126623
Entamoeba histolytica	heat shock protein 90, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma cruzi	heat shock protein 90, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Entamoeba histolytica	heat shock protein 90, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei gambiense	lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Mycobacterium tuberculosis	Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G)	Get druggable targets OG5_126623	All targets in OG5_126623
Loa Loa (eye worm)	endoplasmin	Get druggable targets OG5_126623	All targets in OG5_126623
Neospora caninum	HSP90, related	Get druggable targets OG5_126623	All targets in OG5_126623
Plasmodium berghei	heat shock protein 90, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Toxoplasma gondii	heat shock protein HSP90	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania donovani	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma congolense	Heat shock protein 83, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma congolense	heat shock protein 90, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Trichomonas vaginalis	heat shock protein, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Cryptosporidium parvum	Hsp90	Get druggable targets OG5_126623	All targets in OG5_126623
Wolbachia endosymbiont of Brugia malayi	heat shock protein 90	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei gambiense	Heat shock protein 83, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Schistosoma japonicum	IPR003367,Thrombospondin type 3 repeat;IPR002048,Calcium-binding EF-hand,domain-containing	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Schistosoma japonicum	Heat shock protein HSP 90-alpha, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Candida albicans	heat shock protein	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania braziliensis	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Toxoplasma gondii	heat shock protein 90, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Brugia malayi	Endoplasmin precursor	Get druggable targets OG5_126623	All targets in OG5_126623
Candida albicans	hypothetical protein	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania mexicana	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Echinococcus granulosus	heat shock protein 90	Get druggable targets OG5_126623	All targets in OG5_126623
Echinococcus granulosus	heat shock protein heat shock protein 90 alpha	Get druggable targets OG5_126623	All targets in OG5_126623
Schistosoma mansoni	heat shock protein	Get druggable targets OG5_126623	All targets in OG5_126623
Babesia bovis	hsp90 protein	Get druggable targets OG5_126623	All targets in OG5_126623
Schistosoma japonicum	ko:K09487 heat shock protein 90kDa beta, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Schistosoma mansoni	heat shock protein	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Schistosoma japonicum	ko:K04079 molecular chaperone HtpG, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania mexicana	lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Echinococcus multilocularis	heat shock protein	Get druggable targets OG5_126623	All targets in OG5_126623
Mycobacterium ulcerans	heat shock protein 90	Get druggable targets OG5_126623	All targets in OG5_126623
Trichomonas vaginalis	heat shock protein, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania braziliensis	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma congolense	heat shock protein 90, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Treponema pallidum	heat shock protein 90	Get druggable targets OG5_126623	All targets in OG5_126623
Trichomonas vaginalis	heat shock protein, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Cryptosporidium hominis	heat shock protein 83	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma cruzi	heat shock protein 85, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei	heat shock protein, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei gambiense	Heat shock protein 83, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Plasmodium falciparum	heat shock protein 90	Get druggable targets OG5_126623	All targets in OG5_126623
Plasmodium vivax	endoplasmin, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Mycobacterium leprae	PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G)	Get druggable targets OG5_126623	All targets in OG5_126623
Echinococcus granulosus	heat shock protein	Get druggable targets OG5_126623	All targets in OG5_126623
Schistosoma mansoni	endoplasmin	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania infantum	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Loa Loa (eye worm)	heat shock protein 90	Get druggable targets OG5_126623	All targets in OG5_126623
Trichomonas vaginalis	heat shock protein, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Echinococcus granulosus	heat shock protein 90	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma cruzi	heat shock protein 90, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Echinococcus multilocularis	endoplasmin	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei	heat shock protein, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei	heat shock protein, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania mexicana	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei	Heat shock protein 83, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania infantum	lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei	heat shock protein, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania infantum	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei	heat shock protein 90, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Plasmodium knowlesi	endoplasmin, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Giardia lamblia	Grp94/Hsp90	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma cruzi	heat shock protein 85, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Plasmodium yoelii	putative heat shock protein 81-2	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei	heat shock protein, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei	heat shock protein, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Echinococcus multilocularis	heat shock protein 90	Get druggable targets OG5_126623	All targets in OG5_126623
Candida albicans	heat shock protein	Get druggable targets OG5_126623	All targets in OG5_126623
Theileria parva	heat shock protein 90	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei	heat shock protein, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma cruzi	Heat shock protein 83, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei	heat shock protein, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Schistosoma mansoni	endoplasmin	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania infantum	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Brugia malayi	heat shock protein 90	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Giardia lamblia	Heat shock protein HSP 90-alpha	Get druggable targets OG5_126623	All targets in OG5_126623
Plasmodium knowlesi	heat shock protein 90, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Echinococcus granulosus	endoplasmin	Get druggable targets OG5_126623	All targets in OG5_126623
Trypanosoma brucei	heat shock protein 90, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Plasmodium vivax	heat shock protein 86, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Neospora caninum	HSP90-like protein, related	Get druggable targets OG5_126623	All targets in OG5_126623
Schistosoma japonicum	Heat shock protein 83, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania braziliensis	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Plasmodium yoelii	heat shock 90 kDa protein homolog	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania donovani	heat shock protein 90, putative	Get druggable targets OG5_126623	All targets in OG5_126623
Leishmania major	heat shock protein 83-1	Get druggable targets OG5_126623	All targets in OG5_126623
Schistosoma japonicum	Heat shock protein HSP 90-beta, putative	Get druggable targets OG5_126623	All targets in OG5_126623

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma cruzi	heat shock protein 85, putative	0.0031	0.4617	0.655
Schistosoma mansoni	hypothetical protein	0.0049	1	1
Toxoplasma gondii	heat shock protein 90, putative	0.0039	0.705	1
Echinococcus granulosus	endoplasmin	0.0031	0.4617	0.655
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0024	0.2341	0.2341
Loa Loa (eye worm)	hypothetical protein	0.0049	1	1
Onchocerca volvulus		0.0049	1	1
Trypanosoma brucei	heat shock protein, putative	0.0039	0.705	1
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Trypanosoma brucei	heat shock protein, putative	0.0039	0.705	1
Onchocerca volvulus		0.0049	1	1
Trypanosoma brucei	heat shock protein, putative	0.0039	0.705	1
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Echinococcus granulosus	heat shock protein heat shock protein 90 alpha	0.0031	0.4617	0.655
Treponema pallidum	heat shock protein 90	0.0031	0.4617	0.5
Onchocerca volvulus		0.0049	1	1
Echinococcus multilocularis	endoplasmin	0.0031	0.4617	0.655
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Wolbachia endosymbiont of Brugia malayi	heat shock protein 90	0.0031	0.4617	0.5
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Trypanosoma brucei	heat shock protein, putative	0.0039	0.705	1
Plasmodium falciparum	heat shock protein 90	0.0039	0.705	1
Trypanosoma cruzi	heat shock protein 90, putative	0.0023	0.2156	0.3058
Echinococcus multilocularis	heat shock protein	0.0039	0.705	1
Onchocerca volvulus		0.0049	1	1
Trichomonas vaginalis	heat shock protein, putative	0.0024	0.2432	0.345
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Trichomonas vaginalis	endoplasmin, putative	0.0024	0.2432	0.345
Echinococcus granulosus	heat shock protein 90	0.0039	0.705	1
Echinococcus multilocularis	heat shock protein 90	0.0039	0.705	1
Trypanosoma brucei	heat shock protein, putative	0.0039	0.705	1
Trypanosoma brucei	heat shock protein, putative	0.0039	0.705	1
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Mycobacterium tuberculosis	Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G)	0.0031	0.4617	0.5
Schistosoma mansoni	endoplasmin	0.0039	0.705	0.705
Schistosoma mansoni	heat shock protein	0.0039	0.705	0.705
Trypanosoma brucei	Heat shock protein 83, putative	0.0039	0.705	1
Brugia malayi	Endoplasmin precursor	0.0039	0.705	0.705
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Trypanosoma brucei	heat shock protein 90, putative	0.0039	0.705	1
Plasmodium falciparum	endoplasmin, putative	0.0024	0.2432	0.345
Trypanosoma cruzi	Heat shock protein 83, putative	0.0039	0.705	1
Loa Loa (eye worm)	heat shock protein 90	0.0039	0.705	0.705
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0594	0.0594
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Brugia malayi	SEA domain containing protein	0.0049	1	1
Mycobacterium leprae	PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G)	0.0031	0.4617	0.5
Loa Loa (eye worm)	hypothetical protein	0.0049	1	1
Trypanosoma brucei	heat shock protein, putative	0.0039	0.705	1
Trichomonas vaginalis	heat shock protein, putative	0.0031	0.4617	0.655
Entamoeba histolytica	heat shock protein 90, putative	0.0039	0.705	1
Echinococcus granulosus	heat shock protein	0.0039	0.705	1
Loa Loa (eye worm)	DOMON domain-containing protein	0.0049	1	1
Plasmodium vivax	endoplasmin, putative	0.0039	0.705	1
Trypanosoma cruzi	heat shock protein 85, putative	0.0039	0.705	1
Plasmodium vivax	heat shock protein 86, putative	0.0039	0.705	1
Mycobacterium ulcerans	heat shock protein 90	0.0031	0.4617	0.5
Trypanosoma cruzi	heat shock protein 85, putative	0.0039	0.705	1
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Leishmania major	lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative	0.0031	0.4617	0.655
Trypanosoma brucei	heat shock protein, putative	0.0039	0.705	1
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Trichomonas vaginalis	heat shock protein, putative	0.0031	0.4617	0.655
Loa Loa (eye worm)	endoplasmin	0.0039	0.705	0.705
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Echinococcus granulosus	heat shock protein 90	0.0031	0.4617	0.655
Trypanosoma cruzi	heat shock protein 85, putative	0.0039	0.705	1
Echinococcus multilocularis	heat shock protein 90	0.0031	0.4617	0.655
Brugia malayi	heat shock protein 90	0.0039	0.705	0.705
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Trichomonas vaginalis	heat shock protein, putative	0.0031	0.4617	0.655
Entamoeba histolytica	heat shock protein 90, putative	0.0039	0.705	1
Trypanosoma brucei	heat shock protein 90, putative	0.0039	0.705	1
Onchocerca volvulus		0.0049	1	1
Schistosoma mansoni	endoplasmin	0.0039	0.705	0.705
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0594	0.0594
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Giardia lamblia	Heat shock protein HSP 90-alpha	0.0039	0.705	1
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Trichomonas vaginalis	heat shock protein, putative	0.0039	0.705	1
Brugia malayi	CUB domain containing protein	0.0018	0.0594	0.0594
Trypanosoma cruzi	heat shock protein 90, putative	0.0039	0.705	1
Schistosoma mansoni	heat shock protein	0.0039	0.705	0.705
Toxoplasma gondii	heat shock protein HSP90	0.0039	0.705	1
Leishmania major	heat shock protein 83-1	0.0039	0.705	1
Trypanosoma cruzi	heat shock protein 90, putative	0.0031	0.4617	0.655

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 270 nM	Displacement of GM-FITC from full-length recombinant human Hsp90-alpha after 4 hrs by fluorescence polarization assay	ChEMBL.	24588105
IC50 (functional)	> 1000 nM	Cytotoxicity against human NCI-H460 cells assessed as growth inhibition after 72 hrs by SRB assay	ChEMBL.	24588105

Phenotypes

Whole-cell/tissue/organism interactions

Species name	Source	Reference	Is orphan
Homo sapiens	ChEMBL23	24588105

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3235116

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1879964