Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | maternal embryonic leucine zipper kinase | Starlite/ChEMBL | No references |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | histone deacetylase 7 | 0.0069 | 0.2963 | 0.5254 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0036 | 0 | 0.5 |
Plasmodium vivax | histone deacetylase, putative | 0.0069 | 0.2963 | 0.619 |
Brugia malayi | Histone deacetylase 1 | 0.0089 | 0.4786 | 0.4786 |
Loa Loa (eye worm) | histone deacetylase | 0.0069 | 0.2963 | 0.2963 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0049 | 0.1211 | 0.1211 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0089 | 0.4786 | 0.4786 |
Schistosoma mansoni | histone deacetylase | 0.0089 | 0.4786 | 0.4786 |
Plasmodium falciparum | histone deacetylase 1 | 0.0089 | 0.4786 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.1178 | 0.1178 |
Echinococcus granulosus | histone deacetylase 6 | 0.0076 | 0.3612 | 0.6405 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1178 | 0.1178 |
Echinococcus granulosus | histone deacetylase 7 | 0.0069 | 0.2963 | 0.5254 |
Echinococcus granulosus | serine:threonine protein kinase MARK2 | 0.0049 | 0.1211 | 0.2148 |
Echinococcus granulosus | serine:threonine protein kinase MARK2 | 0.0049 | 0.1211 | 0.2148 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0049 | 0.1211 | 0.1211 |
Echinococcus granulosus | histone deacetylase 1 | 0.0089 | 0.4786 | 0.8488 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0099 | 0.5639 | 0.1636 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0089 | 0.4786 | 0.4786 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0089 | 0.4786 | 1 |
Leishmania major | histone deacetylase, putative | 0.0089 | 0.4786 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.0069 | 0.2963 | 0.5254 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0069 | 0.2963 | 0.5254 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.1178 | 0.1178 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0069 | 0.2963 | 0.2963 |
Schistosoma mansoni | serine/threonine kinase | 0.0148 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0069 | 0.2963 | 0.5254 |
Echinococcus multilocularis | hypothetical protein | 0.0049 | 0.1178 | 0.2089 |
Brugia malayi | Histone deacetylase family protein | 0.0069 | 0.2963 | 0.2963 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0089 | 0.4786 | 0.4786 |
Brugia malayi | Histone deacetylase family protein | 0.0069 | 0.2963 | 0.2963 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0089 | 0.4786 | 1 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0089 | 0.4786 | 0.8488 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0049 | 0.1211 | 0.1211 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0049 | 0.1211 | 0.1211 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0089 | 0.4786 | 1 |
Entamoeba histolytica | histone deacetylase, putative | 0.0089 | 0.4786 | 0.5 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0089 | 0.4786 | 0.4786 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0069 | 0.2963 | 0.619 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0069 | 0.2963 | 0.2963 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0428 | 0.0428 |
Leishmania major | histone deacetylase, putative | 0.0089 | 0.4786 | 1 |
Echinococcus granulosus | histone deacetylase | 0.0069 | 0.2963 | 0.5254 |
Brugia malayi | Kinase associated domain 1 family protein | 0.0049 | 0.1178 | 0.1178 |
Trypanosoma brucei | histone deacetylase 3 | 0.0069 | 0.2963 | 0.619 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0076 | 0.3612 | 0.6405 |
Trypanosoma brucei | histone deacetylase 4 | 0.0069 | 0.2963 | 0.619 |
Trypanosoma brucei | histone deacetylase 1 | 0.0089 | 0.4786 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0099 | 0.5639 | 0.1636 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0069 | 0.2963 | 0.619 |
Echinococcus granulosus | histone deacetylase 3 | 0.0089 | 0.4786 | 0.8488 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0089 | 0.4786 | 0.8488 |
Giardia lamblia | Histone deacetylase | 0.0089 | 0.4786 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0069 | 0.2963 | 0.619 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0089 | 0.4786 | 1 |
Schistosoma mansoni | histone deacetylase | 0.0089 | 0.4786 | 0.4786 |
Echinococcus multilocularis | serine:threonine protein kinase MARK2 | 0.0049 | 0.1211 | 0.2148 |
Echinococcus multilocularis | serine:threonine protein kinase MARK2 | 0.0049 | 0.1211 | 0.2148 |
Echinococcus multilocularis | maternal embryonic leucine zipper kinase | 0.0099 | 0.5639 | 1 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0069 | 0.2963 | 0.2963 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.4786 | 0.4786 |
Loa Loa (eye worm) | CAMK/CAMKL/MELK protein kinase | 0.0148 | 1 | 1 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0069 | 0.2963 | 0.619 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0148 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.0069 | 0.2963 | 0.5254 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0089 | 0.4786 | 1 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0076 | 0.3612 | 0.3612 |
Echinococcus multilocularis | calcium activated potassium channel | 0.0049 | 0.1211 | 0.2148 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0049 | 0.1211 | 0.1211 |
Echinococcus granulosus | calcium activated potassium channel | 0.0049 | 0.1211 | 0.2148 |
Trypanosoma brucei | histone deacetylase, putative | 0.0069 | 0.2963 | 0.619 |
Echinococcus multilocularis | histone deacetylase | 0.0069 | 0.2963 | 0.5254 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0069 | 0.2963 | 0.619 |
Echinococcus granulosus | maternal embryonic leucine zipper kinase | 0.0099 | 0.5639 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.