Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | tryptophan hydroxylase | 0.0107 | 0.0363 | 0.0467 |
Loa Loa (eye worm) | integrin beta-2 | 0.0378 | 0.2599 | 1 |
Brugia malayi | Integrin alpha cytoplasmic region family protein | 0.014 | 0.0635 | 0.122 |
Echinococcus multilocularis | integrin alpha 3 | 0.0142 | 0.0651 | 0.1156 |
Loa Loa (eye worm) | tryptophan hydroxylase 1 | 0.0107 | 0.0363 | 0.0169 |
Wolbachia endosymbiont of Brugia malayi | phosphoribosylamine--glycine ligase | 0.0283 | 0.1816 | 1 |
Echinococcus granulosus | folate receptor beta | 0.0591 | 0.4352 | 1 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Schistosoma mansoni | tyrosine 3-monooxygenase | 0.0107 | 0.0363 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0635 | 0.1368 |
Mycobacterium ulcerans | phosphoribosylamine--glycine ligase | 0.0283 | 0.1816 | 1 |
Echinococcus granulosus | integrin beta 2 | 0.028 | 0.1792 | 0.3883 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.0679 | 0.156 |
Toxoplasma gondii | phenylalanine-4-hydroxylase | 0.0348 | 0.2353 | 1 |
Schistosoma mansoni | integrin alpha | 0.0185 | 0.1006 | 0.0853 |
Leishmania major | phenylalanine-4-hydroxylase,phenylalanine-4-hydroxylase, putative | 0.0315 | 0.2083 | 0.5 |
Schistosoma mansoni | tyrosine/tryptophan monooxygenase | 0.0107 | 0.0363 | 0.0199 |
Schistosoma mansoni | integrin beta subunit | 0.0223 | 0.1319 | 0.1172 |
Brugia malayi | Integrin alpha pat-2 precursor | 0.0185 | 0.1006 | 0.2875 |
Echinococcus granulosus | tryptophan hydroxylase | 0.0107 | 0.0363 | 0.0467 |
Loa Loa (eye worm) | integrin alpha pat-2 | 0.0285 | 0.1829 | 0.6614 |
Schistosoma mansoni | family A2 unassigned peptidase (A02 family) | 0.0232 | 0.1397 | 0.1251 |
Mycobacterium leprae | PROBABLE PHOSPHORIBOSYLAMINE--GLYCINE LIGASE PURD (GARS) (GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE SYNT | 0.0283 | 0.1816 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0363 | 0.0169 |
Echinococcus multilocularis | integrin beta 2 | 0.028 | 0.1792 | 0.3883 |
Mycobacterium tuberculosis | Probable phosphoribosylformylglycinamidine CYCLO-ligase PurM (AIRS) (phosphoribosyl-aminoimidazole synthetase) (air synthase) | 0.0062 | 0 | 0.5 |
Echinococcus multilocularis | folate receptor beta | 0.0591 | 0.4352 | 1 |
Echinococcus granulosus | integrin alpha 3 | 0.0142 | 0.0651 | 0.1156 |
Toxoplasma gondii | aromatic amino acid hydrolase AAH1 | 0.0315 | 0.2083 | 0.8383 |
Toxoplasma gondii | aromatic amino acid hydrolase AAH2 | 0.0348 | 0.2353 | 1 |
Brugia malayi | Integrin beta pat-3 precursor | 0.0378 | 0.2599 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.