Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | neurogenic locus notch protein | 0.0028 | 0.5 | 0.5 |
Schistosoma mansoni | slit | 0.0028 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.5 | 0.5 |
Echinococcus granulosus | pikachurin | 0.0028 | 0.5 | 0.5 |
Brugia malayi | EGF-like domain containing protein | 0.0028 | 0.5 | 0.5 |
Loa Loa (eye worm) | abnormal epIthelia family member | 0.0028 | 0.5 | 0.5 |
Echinococcus multilocularis | slit 2 protein | 0.0028 | 0.5 | 0.5 |
Brugia malayi | laminin alpha chain | 0.0028 | 0.5 | 0.5 |
Schistosoma mansoni | chondroitin sulfate proteoglycan-related | 0.0028 | 0.5 | 0.5 |
Schistosoma mansoni | cell polarity protein | 0.0028 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.5 | 0.5 |
Echinococcus multilocularis | pikachurin | 0.0028 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.5 | 0.5 |
Brugia malayi | Thrombospondin N-terminal -like domain containing protein | 0.0028 | 0.5 | 0.5 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0028 | 0.5 | 0.5 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0028 | 0.5 | 0.5 |
Echinococcus granulosus | slit 2 protein | 0.0028 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.