TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 304.434 | Formula: C14H16N4S2
H donors: 1 H acceptors: 2 LogP: 2.11 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: CC(Cn1cccn1)NCc1csc(n1)c1cccs1
InChi: 1S/C14H16N4S2/c1-11(9-18-6-3-5-16-18)15-8-12-10-20-14(17-12)13-4-2-7-19-13/h2-7,10-11,15H,8-9H2,1H3
InChiKey: QLJZFNLRLBPVOS-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0137	0.1359	0.2087
Loa Loa (eye worm)	hypothetical protein	0.0232	0.2572	0.4337
Brugia malayi	nuclear receptor NHR-88	0.0492	0.5874	1
Entamoeba histolytica	hypothetical protein	0.0109	0.1012	0.5
Brugia malayi	Nuclear hormone receptor-like 1	0.026	0.2925	0.498
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.0108	0.0999	1
Loa Loa (eye worm)	hypothetical protein	0.0232	0.2572	0.4337
Loa Loa (eye worm)	hypothetical protein	0.0232	0.2572	0.4337
Brugia malayi	hypothetical protein	0.0046	0.0207	0.0353
Brugia malayi	nuclear hormone receptor family member nhr-6	0.0232	0.2572	0.4378
Echinococcus multilocularis	nuclear receptor nhr 48	0.0232	0.2572	0.254
Plasmodium falciparum	ataxin-2 like protein, putative	0.0046	0.0207	1
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0232	0.2572	0.254
Echinococcus granulosus	snurportin 1	0.0352	0.4103	0.6436
Loa Loa (eye worm)	hypothetical protein	0.0217	0.2385	0.4017
Loa Loa (eye worm)	hypothetical protein	0.026	0.2925	0.4943
Loa Loa (eye worm)	hypothetical protein	0.0232	0.2572	0.4337
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0492	0.5874	0.5857
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0069	0.0497	0.072
Entamoeba histolytica	hypothetical protein	0.0109	0.1012	0.5
Onchocerca volvulus	Protein ultraspiracle homolog	0.0492	0.5874	1
Brugia malayi	tailless protein	0.0232	0.2572	0.4378
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0492	0.5874	0.9244
Brugia malayi	hypothetical protein	0.0232	0.2572	0.4378
Echinococcus multilocularis	snurportin 1	0.0352	0.4103	0.4078
Loa Loa (eye worm)	fli-1 protein	0.0233	0.259	0.4368
Brugia malayi	TAR-binding protein	0.0045	0.0198	0.0338
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0492	0.5874	1
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0492	0.5874	0.9244
Schistosoma mansoni	hypothetical protein	0.0529	0.6351	1
Toxoplasma gondii	LsmAD domain-containing protein	0.0046	0.0207	1
Brugia malayi	steroid hormone receptor	0.0492	0.5874	1
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.026	0.2925	0.2895
Plasmodium falciparum	thioredoxin reductase	0.0043	0.0165	0.746
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0352	0.4103	0.6962
Loa Loa (eye worm)	hypothetical protein	0.026	0.2925	0.4943
Loa Loa (eye worm)	DR-78	0.0232	0.2572	0.4337
Loa Loa (eye worm)	hypothetical protein	0.0492	0.5874	1
Schistosoma mansoni	tar DNA-binding protein	0.0045	0.0198	0.0248
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0492	0.5874	1
Plasmodium falciparum	glutathione reductase	0.0043	0.0165	0.746
Schistosoma mansoni	ets-related	0.0233	0.259	0.4038
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0492	0.5874	1
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0492	0.5874	0.5857
Loa Loa (eye worm)	RNA binding protein	0.0045	0.0198	0.0268
Mycobacterium tuberculosis	Probable reductase	0.0097	0.0861	0.8342
Echinococcus granulosus	GA binding protein alpha chain	0.0077	0.06	0.0884
Brugia malayi	nuclear hormone receptor family member odr-7	0.0232	0.2572	0.4378
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0492	0.5874	1
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.026	0.2925	0.457
Loa Loa (eye worm)	hypothetical protein	0.0492	0.5874	1
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.0232	0.2572	0.4337
Schistosoma mansoni	hypothetical protein	0.0148	0.1511	0.2328
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0217	0.2385	0.406
Brugia malayi	Latrophilin receptor protein 2	0.0069	0.0497	0.0845
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0492	0.5874	0.9244
Schistosoma mansoni	tar DNA-binding protein	0.0045	0.0198	0.0248
Plasmodium vivax	ataxin-2 like protein, putative	0.0046	0.0207	1
Echinococcus multilocularis	FTZ F1 alpha	0.0492	0.5874	0.5857
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0217	0.2385	0.406
Brugia malayi	ecdysteroid receptor	0.0492	0.5874	1
Loa Loa (eye worm)	hypothetical protein	0.0232	0.2572	0.4337
Trypanosoma brucei	PAB1-binding protein , putative	0.0046	0.0207	1
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0069	0.0497	0.0845
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0137	0.1359	0.2313
Brugia malayi	RNA binding protein	0.0045	0.0198	0.0338
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0492	0.5874	1
Loa Loa (eye worm)	steroid hormone receptor	0.0492	0.5874	1
Echinococcus multilocularis	ecdysone induced protein 78C	0.0492	0.5874	0.5857
Loa Loa (eye worm)	hypothetical protein	0.0492	0.5874	1
Plasmodium falciparum	ataxin-2 like protein, putative	0.0046	0.0207	1
Schistosoma mansoni	thyroid hormone receptor	0.0492	0.5874	0.9244
Mycobacterium tuberculosis	Probable dehydrogenase	0.0097	0.0861	0.8342
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0492	0.5874	1
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0492	0.5874	1
Brugia malayi	hypothetical protein	0.026	0.2925	0.498
Echinococcus granulosus	thyroid hormone receptor alpha	0.0232	0.2572	0.4009
Loa Loa (eye worm)	hypothetical protein	0.0492	0.5874	1
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0232	0.2572	0.4009
Schistosoma mansoni	nuclear hormone receptor	0.0232	0.2572	0.4009
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0492	0.5874	0.9244
Loa Loa (eye worm)	hypothetical protein	0.0069	0.0497	0.0779
Loa Loa (eye worm)	hypothetical protein	0.0148	0.1511	0.2518
Echinococcus granulosus	geminin	0.0529	0.6351	1
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0492	0.5874	0.9244
Echinococcus multilocularis	tar DNA binding protein	0.0045	0.0198	0.0157
Schistosoma mansoni	hypothetical protein	0.0069	0.0497	0.072
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.0232	0.2572	0.4009
Loa Loa (eye worm)	hypothetical protein	0.026	0.2925	0.4943
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0492	0.5874	0.5857
Schistosoma mansoni	hypothetical protein	0.0069	0.0497	0.072
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0137	0.1359	0.2257
Onchocerca volvulus		0.0492	0.5874	1
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0492	0.5874	0.9244
Schistosoma mansoni	nuclear hormone receptor	0.0492	0.5874	0.9244
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0043	0.0165	0.0124
Loa Loa (eye worm)	hypothetical protein	0.0066	0.0458	0.0713
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0109	0.1012	0.1538
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0492	0.5874	0.9244
Brugia malayi	hypothetical protein	0.026	0.2925	0.498
Schistosoma mansoni	hypothetical protein	0.0352	0.4103	0.6436
Schistosoma mansoni	nuclear hormone receptor	0.0232	0.2572	0.4009
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0492	0.5874	1
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0492	0.5874	0.5857
Brugia malayi	glutathione reductase	0.0043	0.0165	0.0281
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0069	0.0497	0.0779
Brugia malayi	nuclear receptor NHR-88	0.0232	0.2572	0.4378
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0097	0.0861	0.8342
Loa Loa (eye worm)	transcription factor SMAD2	0.0108	0.0993	0.1631
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0232	0.2572	0.254
Brugia malayi	Nuclear hormone receptor-like 1	0.0492	0.5874	1
Brugia malayi	Nuclear hormone receptor E75	0.0232	0.2572	0.4378
Leishmania major	hypothetical protein, conserved	0.0046	0.0207	1
Plasmodium vivax	glutathione reductase, putative	0.0043	0.0165	0.746
Loa Loa (eye worm)	hypothetical protein	0.0232	0.2572	0.4337
Schistosoma mansoni	tar DNA-binding protein	0.0045	0.0198	0.0248
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0232	0.2572	0.4009
Mycobacterium tuberculosis	Probable oxidoreductase	0.0108	0.0999	1
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0492	0.5874	0.9244
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0492	0.5874	0.9244
Brugia malayi	conserved hypotetical protein	0.0232	0.2572	0.4378
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0137	0.1359	0.1322
Loa Loa (eye worm)	D-ets-4 DNA binding domain-containing protein	0.0077	0.06	0.0956
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0492	0.5874	0.9244
Echinococcus multilocularis	geminin	0.0529	0.6351	0.6336
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0232	0.2572	0.4009
Schistosoma mansoni	hypothetical protein	0.0069	0.0497	0.072
Loa Loa (eye worm)	nuclear hormone receptor	0.0232	0.2572	0.4337
Loa Loa (eye worm)	thioredoxin reductase	0.0043	0.0165	0.0211
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0492	0.5874	1
Echinococcus granulosus	tar DNA binding protein	0.0045	0.0198	0.0248
Brugia malayi	Thioredoxin reductase	0.0043	0.0165	0.0281
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0492	0.5874	1
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0097	0.0861	0.8342
Brugia malayi	RNA recognition motif domain containing protein	0.0045	0.0198	0.0338
Loa Loa (eye worm)	hypothetical protein	0.0232	0.2572	0.4337
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0492	0.5874	0.5857
Brugia malayi	hypothetical protein	0.0232	0.2572	0.4378
Loa Loa (eye worm)	hypothetical protein	0.0232	0.2572	0.4337
Brugia malayi	Nuclear hormone receptor E75	0.0232	0.2572	0.4378
Brugia malayi	Importin beta-1 subunit	0.0033	0.0042	0.0072
Loa Loa (eye worm)	nuclear receptor NHR-67	0.0232	0.2572	0.4337
Loa Loa (eye worm)	hypothetical protein	0.0232	0.2572	0.4337
Entamoeba histolytica	hypothetical protein	0.0109	0.1012	0.5
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0492	0.5874	1
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.026	0.2925	0.4943
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0492	0.5874	0.9244
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0045	0.0198	0.0268
Echinococcus granulosus	thioredoxin glutathione reductase	0.0043	0.0165	0.0195
Brugia malayi	MH2 domain containing protein	0.0108	0.0993	0.1691
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.0232	0.2572	0.254
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0097	0.0861	0.8342
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0492	0.5874	1
Trypanosoma brucei	trypanothione reductase	0.0043	0.0165	0.746
Schistosoma mansoni	nuclear receptor nhr-48	0.0232	0.2572	0.4009
Brugia malayi	orphan nuclear receptor NR2E1	0.0232	0.2572	0.4378
Brugia malayi	nuclear hormone receptor	0.0232	0.2572	0.4378
Loa Loa (eye worm)	hypothetical protein	0.0492	0.5874	1
Echinococcus multilocularis	GPCR, family 2	0.0069	0.0497	0.0456
Echinococcus granulosus	ecdysone induced protein 78C	0.0492	0.5874	0.9244
Brugia malayi	photoreceptor-specific nuclear receptor	0.0492	0.5874	1
Loa Loa (eye worm)	hypothetical protein	0.0232	0.2572	0.4337
Schistosoma mansoni	tar DNA-binding protein	0.0045	0.0198	0.0248
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0069	0.0497	0.072
Schistosoma mansoni	zinc finger protein	0.0232	0.2572	0.4009
Loa Loa (eye worm)	hypothetical protein	0.0232	0.2572	0.4337
Schistosoma mansoni	hypothetical protein	0.0109	0.1012	0.1538
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0492	0.5874	1
Schistosoma mansoni	nuclear receptor	0.0232	0.2572	0.4009
Loa Loa (eye worm)	hypothetical protein	0.026	0.2925	0.4943
Brugia malayi	nuclear hormone receptor	0.0492	0.5874	1
Brugia malayi	nuclear receptor RXR	0.026	0.2925	0.498
Loa Loa (eye worm)	hypothetical protein	0.0492	0.5874	1
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.0232	0.2572	0.4009
Brugia malayi	nuclear receptor NHR-67	0.0232	0.2572	0.4378
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.0232	0.2572	0.4009
Brugia malayi	nuclear receptor RXR	0.0232	0.2572	0.4378
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0137	0.1359	0.2087
Schistosoma mansoni	coup transcription factor	0.0492	0.5874	0.9244
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0069	0.0497	0.0456
Loa Loa (eye worm)	hypothetical protein	0.0232	0.2572	0.4337
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0492	0.5874	0.9244
Loa Loa (eye worm)	hypothetical protein	0.0492	0.5874	1
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0492	0.5874	1
Loa Loa (eye worm)	hypothetical protein	0.0492	0.5874	1
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0492	0.5874	1
Toxoplasma gondii	thioredoxin reductase	0.0043	0.0165	0.746
Schistosoma mansoni	hypothetical protein	0.0069	0.0497	0.072
Trypanosoma cruzi	PAB1-binding protein , putative	0.0046	0.0207	1
Echinococcus granulosus	nuclear receptor nhr 48	0.0232	0.2572	0.4009
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.026	0.2925	0.457
Trypanosoma cruzi	PAB1-binding protein , putative	0.0046	0.0207	1
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0492	0.5874	1
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0232	0.2572	0.254
Loa Loa (eye worm)	hypothetical protein	0.026	0.2925	0.4943
Loa Loa (eye worm)	glutathione reductase	0.0043	0.0165	0.0211
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0109	0.1012	0.0974
Loa Loa (eye worm)	MH2 domain-containing protein	0.0108	0.0993	0.1631
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0492	0.5874	1
Brugia malayi	latrophilin 2 splice variant baaae	0.0148	0.1511	0.2572
Entamoeba histolytica	hypothetical protein	0.0109	0.1012	0.5
Schistosoma mansoni	hypothetical protein	0.0529	0.6351	1
Brugia malayi	ecdysone receptor	0.0232	0.2572	0.4378
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0492	0.5874	0.9244
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0097	0.0861	0.8342
Schistosoma mansoni	retinoic acid receptor RXR	0.0492	0.5874	0.9244
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0137	0.1359	0.2087
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0108	0.0999	1
Brugia malayi	hypothetical protein	0.0109	0.1012	0.1723
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.0108	0.0999	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0492	0.5874	1
Schistosoma mansoni	thyroid hormone receptor	0.0492	0.5874	0.9244
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0217	0.2385	0.4017
Brugia malayi	RNA, U transporter 1	0.0094	0.0816	0.1389
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.0232	0.2572	0.4378
Brugia malayi	Ets-domain containing protein	0.0077	0.06	0.1021
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0492	0.5874	0.5857
Brugia malayi	Nuclear hormone receptor-like 1	0.026	0.2925	0.498
Schistosoma mansoni	RAR-like nuclear receptor	0.0492	0.5874	0.9244
Schistosoma mansoni	tar DNA-binding protein	0.0045	0.0198	0.0248
Echinococcus granulosus	FTZ F1 alpha	0.0492	0.5874	0.9244
Echinococcus granulosus	GPCR family 2	0.0069	0.0497	0.072
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0492	0.5874	0.5857
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0207	0.0283
Loa Loa (eye worm)	TAR-binding protein	0.0045	0.0198	0.0268
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0137	0.1359	0.2087
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0492	0.5874	0.9244
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0069	0.0497	0.0456
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0492	0.5874	1
Brugia malayi	Ets-domain containing protein	0.0077	0.06	0.1021
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0492	0.5874	1
Plasmodium vivax	thioredoxin reductase, putative	0.0043	0.0165	0.746
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0137	0.1359	0.2087
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.0232	0.2572	0.254
Onchocerca volvulus	Bile acid receptor homolog	0.0492	0.5874	1
Brugia malayi	Steroid receptor seven-up type 2	0.0492	0.5874	1
Schistosoma mansoni	gabp alpha	0.0077	0.06	0.0884
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0137	0.1359	0.1322
Schistosoma mansoni	nuclear receptor	0.0232	0.2572	0.4009
Echinococcus multilocularis	GA binding protein alpha chain	0.0077	0.06	0.056
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0492	0.5874	1
Loa Loa (eye worm)	hypothetical protein	0.0232	0.2572	0.4337
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.026	0.2925	0.457
Brugia malayi	Fli-1 protein	0.0233	0.259	0.4409
Schistosoma mansoni	transcription factor LCR-F1	0.0109	0.1012	0.1538

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3496604

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 2070443