Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | acetylcholinesterase | 0.0105 | 1 | 1 |
Leishmania major | peter pan protein, putative | 0.0075 | 0.6526 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0023 | 0.0605 | 0.0605 |
Echinococcus multilocularis | peter pan | 0.0075 | 0.6526 | 0.6526 |
Loa Loa (eye worm) | carboxylesterase | 0.0105 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0023 | 0.0605 | 1 |
Trypanosoma cruzi | peter pan protein, putative | 0.0075 | 0.6526 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0605 | 0.0605 |
Echinococcus granulosus | acetylcholinesterase | 0.0105 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0605 | 0.0605 |
Toxoplasma gondii | brix domain-containing protein | 0.0075 | 0.6526 | 0.5 |
Trypanosoma brucei | brix domain containing protein, putative | 0.0075 | 0.6526 | 1 |
Echinococcus granulosus | peter pan | 0.0075 | 0.6526 | 0.6526 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0018 | 0 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0605 | 0.0605 |
Echinococcus granulosus | carboxylesterase 5A | 0.0105 | 1 | 1 |
Schistosoma mansoni | peter pan-related | 0.0075 | 0.6526 | 0.6526 |
Echinococcus granulosus | acetylcholinesterase | 0.0105 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0105 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0105 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0105 | 1 | 1 |
Plasmodium falciparum | BRIX domain, putative | 0.0075 | 0.6526 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0018 | 0 | 0.5 |
Schistosoma mansoni | peter pan-related | 0.0075 | 0.6526 | 0.6526 |
Giardia lamblia | Peter pan protein | 0.0075 | 0.6526 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 1 | 1 |
Echinococcus multilocularis | zinc finger protein 598 | 0.0075 | 0.6473 | 0.6473 |
Brugia malayi | Brix domain containing protein | 0.0075 | 0.6526 | 0.6526 |
Loa Loa (eye worm) | brix domain-containing protein | 0.0075 | 0.6526 | 0.6526 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0034 | 0.1792 | 0.1792 |
Trichomonas vaginalis | ssf, putative | 0.0075 | 0.6526 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0105 | 1 | 1 |
Trypanosoma cruzi | peter pan protein, putative | 0.0075 | 0.6526 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0605 | 0.0605 |
Brugia malayi | Cytochrome P450 family protein | 0.0034 | 0.1792 | 0.1792 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0105 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0075 | 0.6526 | 0.5 |
Onchocerca volvulus | Peter pan protein homolog | 0.0075 | 0.6526 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0018 | 0 | 0.5 |
Entamoeba histolytica | brix domain containing protein | 0.0075 | 0.6526 | 0.5 |
Echinococcus granulosus | zinc finger protein 598 | 0.0075 | 0.6473 | 0.6473 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.