Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Papain family cysteine protease containing protein | 0.0037 | 0.0179 | 0.0343 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0295 | 0.037 |
Echinococcus multilocularis | 0.0122 | 0.1218 | 0.1218 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0172 | 0.033 |
Brugia malayi | celfurPC protein | 0.0122 | 0.1218 | 0.2331 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0849 | 0.5287 |
Onchocerca volvulus | 0.012 | 0.12 | 0.9501 | |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0063 | 0.0496 | 0.062 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0044 | 0.0266 | 0.0266 |
Entamoeba histolytica | cysteine protease, putative | 0.0037 | 0.0179 | 0.7151 |
Leishmania major | hypothetical protein, conserved | 0.0063 | 0.0497 | 0.2277 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0079 | 0.0282 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0042 | 0.0237 | 0.0453 |
Echinococcus granulosus | calpain A | 0.0063 | 0.0496 | 0.062 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0079 | 0.0282 |
Trichomonas vaginalis | cyclins, putative | 0.0042 | 0.0237 | 0.1305 |
Trichomonas vaginalis | cyclins, putative | 0.0042 | 0.0237 | 0.1305 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0037 | 0.0179 | 0.3112 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0037 | 0.0179 | 0.3112 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0042 | 0.0237 | 0.0387 |
Brugia malayi | calpain family protein 1 | 0.006 | 0.0462 | 0.0884 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0172 | 0.033 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0079 | 0.0282 |
Brugia malayi | Protein kinase domain containing protein | 0.0063 | 0.0497 | 0.0951 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Loa Loa (eye worm) | proprotein convertase 2 | 0.0036 | 0.0159 | 0.0303 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0037 | 0.0179 | 0.0225 |
Onchocerca volvulus | 0.0037 | 0.0179 | 0.1421 | |
Giardia lamblia | Cathepsin B precursor | 0.0151 | 0.1574 | 1 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0034 | 0.0136 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.0082 | 0.0156 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0172 | 0.033 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0037 | 0.0179 | 0.0343 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0185 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0237 | 0.0453 |
Trichomonas vaginalis | leucine-rich repeat protein, BspA family | 0.0029 | 0.0079 | 0.0282 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0036 | 0.0159 | 0.0798 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0172 | 0.033 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.012 | 0.12 | 0.1502 |
Trypanosoma cruzi | cyclin, putative | 0.0042 | 0.0237 | 0.0387 |
Onchocerca volvulus | 0.0042 | 0.0237 | 0.1874 | |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0063 | 0.0496 | 0.062 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0849 | 0.5287 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0448 | 0.5227 | 1 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0151 | 0.1574 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0295 | 0.0295 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0172 | 0.033 |
Onchocerca volvulus | 0.0037 | 0.0172 | 0.1365 | |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0036 | 0.0159 | 0.0798 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0037 | 0.0179 | 0.0933 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0037 | 0.0179 | 0.0933 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0082 | 0.0156 |
Onchocerca volvulus | 0.0037 | 0.0179 | 0.1421 | |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0037 | 0.0172 | 0.033 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0185 | 0.0969 |
Onchocerca volvulus | Cathepsin F homolog | 0.0037 | 0.0179 | 0.1421 |
Trichomonas vaginalis | hypothetical protein | 0.0029 | 0.0079 | 0.0282 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0038 | 0.0185 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0672 | 0.799 | 0.799 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0029 | 0.0082 | 0.2275 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0037 | 0.0179 | 0.0933 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0672 | 0.799 | 1 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0057 | 0.0415 | 0.0415 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0462 | 0.0884 |
Onchocerca volvulus | 0.0037 | 0.0172 | 0.1365 | |
Loa Loa (eye worm) | cysteine protease | 0.0037 | 0.0179 | 0.0343 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0037 | 0.0179 | 0.0276 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0172 | 0.033 |
Giardia lamblia | Cathepsin B precursor | 0.0151 | 0.1574 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0026 | 0.0036 | 0.0045 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0037 | 0.0179 | 0.0933 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0449 | 0.0858 |
Schistosoma mansoni | furin-1 (S08 family) | 0.0066 | 0.0528 | 0.0661 |
Echinococcus granulosus | furin | 0.0151 | 0.1578 | 0.1975 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0172 | 0.033 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0038 | 0.0185 | 0.0185 |
Onchocerca volvulus | 0.0037 | 0.0172 | 0.1365 | |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0185 | 0.0969 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0063 | 0.0496 | 0.0496 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0037 | 0.0179 | 0.0225 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0079 | 0.0282 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0042 | 0.0237 | 0.1053 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0185 | 0.0287 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0079 | 0.0099 |
Trichomonas vaginalis | proprotein convertase subtilisin/kexin type, putative | 0.0029 | 0.0079 | 0.0282 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0037 | 0.0179 | 0.0276 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0179 | 0.0343 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0063 | 0.0497 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0037 | 0.0179 | 0.0933 |
Echinococcus multilocularis | cysteine protease | 0.0037 | 0.0179 | 0.0179 |
Entamoeba histolytica | cyclin, putative | 0.0042 | 0.0237 | 1 |
Schistosoma mansoni | subfamily S8B unassigned peptidase (S08 family) | 0.0151 | 0.1578 | 0.1975 |
Schistosoma mansoni | lipoxygenase | 0.0057 | 0.0415 | 0.052 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0037 | 0.0179 | 0.0225 |
Onchocerca volvulus | 0.0029 | 0.0082 | 0.0646 | |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0037 | 0.0172 | 0.033 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0295 | 0.0295 |
Echinococcus multilocularis | cathepsin b | 0.0448 | 0.5227 | 0.5227 |
Echinococcus multilocularis | cysteine protease | 0.0037 | 0.0179 | 0.0179 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0172 | 0.033 |
Echinococcus multilocularis | neuroendocrine convertase 2 | 0.0095 | 0.0887 | 0.0887 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0037 | 0.0179 | 0.7151 |
Trichomonas vaginalis | cyclin B, putative | 0.0042 | 0.0237 | 0.1305 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0057 | 0.0415 | 0.052 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0172 | 0.033 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0295 | 0.037 |
Onchocerca volvulus | 0.0037 | 0.0172 | 0.1365 | |
Echinococcus multilocularis | calpain A | 0.0063 | 0.0496 | 0.0496 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0036 | 0.0159 | 0.0798 |
Brugia malayi | neuroendocrine convertase 1 precursor | 0.0095 | 0.0887 | 0.1698 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0448 | 0.5227 | 0.6542 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0036 | 0.0159 | 0.0798 |
Onchocerca volvulus | Huntingtin homolog | 0.0125 | 0.1263 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.0082 | 0.0297 |
Brugia malayi | hypothetical protein | 0.0125 | 0.1263 | 0.2416 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0037 | 0.0179 | 0.7151 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0448 | 0.5227 | 0.6542 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0172 | 0.033 |
Onchocerca volvulus | 0.0038 | 0.0182 | 0.1442 | |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0497 | 0.0622 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0079 | 0.0282 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Onchocerca volvulus | 0.0037 | 0.0172 | 0.1365 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0237 | 0.0453 |
Onchocerca volvulus | 0.0037 | 0.0179 | 0.1421 | |
Echinococcus multilocularis | cathepsin b | 0.0448 | 0.5227 | 0.5227 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0037 | 0.0179 | 0.0933 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0037 | 0.0179 | 0.0179 |
Onchocerca volvulus | 0.0037 | 0.0172 | 0.1365 | |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0179 | 0.0343 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0063 | 0.0496 | 0.062 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0029 | 0.0082 | 0.0088 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0037 | 0.0172 | 0.033 |
Brugia malayi | cathepsin L-like precursor | 0.0029 | 0.0082 | 0.0156 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0026 | 0.0036 | 0.0069 |
Brugia malayi | Inositol-1 | 0.0038 | 0.0185 | 0.0354 |
Echinococcus granulosus | cathepsin b | 0.0448 | 0.5227 | 0.6542 |
Toxoplasma gondii | subtilisin SUB12 | 0.0043 | 0.0252 | 0.0211 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0037 | 0.0179 | 0.0933 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0037 | 0.0179 | 0.0179 |
Echinococcus granulosus | cathepsin b | 0.0448 | 0.5227 | 0.6542 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0063 | 0.0497 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0038 | 0.0185 | 0.0969 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0185 | 0.0232 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0063 | 0.0497 | 0.0622 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0151 | 0.1574 | 0.197 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0037 | 0.0179 | 0.0276 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0029 | 0.0082 | 0.0156 |
Trichomonas vaginalis | cyclin B, putative | 0.0042 | 0.0237 | 0.1305 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0448 | 0.5227 | 0.6542 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0079 | 0.0282 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.006 | 0.0462 | 0.0578 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0042 | 0.0237 | 0.1305 |
Echinococcus granulosus | proprotein convertase subtilisin:kexin type 5 | 0.0092 | 0.0849 | 0.1063 |
Echinococcus granulosus | cathepsin l1 | 0.0037 | 0.0179 | 0.0225 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0044 | 0.0266 | 0.0509 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0037 | 0.0172 | 0.033 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0151 | 0.1574 | 1 |
Onchocerca volvulus | 0.0037 | 0.0179 | 0.1421 | |
Brugia malayi | proprotein convertase 2 | 0.0095 | 0.0887 | 0.1698 |
Brugia malayi | calpain family protein 1 | 0.006 | 0.0462 | 0.0884 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Toxoplasma gondii | kringle domain-containing protein | 0.0063 | 0.0497 | 0.0863 |
Toxoplasma gondii | PAN domain-containing protein | 0.0342 | 0.3932 | 1 |
Plasmodium vivax | vivapain-2 | 0.0037 | 0.0179 | 0.3112 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0037 | 0.0179 | 0.0933 |
Onchocerca volvulus | 0.0037 | 0.0172 | 0.1365 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0179 | 0.0343 |
Loa Loa (eye worm) | inositol-1 | 0.0038 | 0.0185 | 0.0354 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0063 | 0.0497 | 0.0951 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0082 | 0.0156 |
Echinococcus granulosus | cathepsin L | 0.0026 | 0.0036 | 0.0045 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0266 | 0.0509 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0172 | 0.033 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0038 | 0.0185 | 0.0034 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.0082 | 0.0156 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0037 | 0.0179 | 0.0276 |
Brugia malayi | endoprotease bli-4 precursor | 0.0151 | 0.1578 | 0.3018 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0151 | 0.1574 | 1 |
Schistosoma mansoni | cyclin B | 0.0042 | 0.0237 | 0.0296 |
Echinococcus multilocularis | cathepsin L | 0.0026 | 0.0036 | 0.0036 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0179 | 0.0343 |
Trichomonas vaginalis | neuroendocrine convertase 2 precursor, putative | 0.0029 | 0.0079 | 0.0282 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0037 | 0.0179 | 0.0179 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0172 | 0.033 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0063 | 0.0497 | 0.0497 |
Giardia lamblia | Cathepsin B precursor | 0.0151 | 0.1574 | 1 |
Brugia malayi | Kringle domain containing protein | 0.0063 | 0.0497 | 0.0951 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0295 | 0.037 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0172 | 0.033 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0037 | 0.0179 | 0.0179 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Onchocerca volvulus | 0.0037 | 0.0172 | 0.1365 | |
Trichomonas vaginalis | cyclin A, putative | 0.0042 | 0.0237 | 0.1305 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0037 | 0.0179 | 0.0933 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0026 | 0.0036 | 0.0045 |
Toxoplasma gondii | PAN domain-containing protein | 0.0342 | 0.3932 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0037 | 0.0179 | 0.1421 |
Echinococcus multilocularis | proprotein convertase subtilisin:kexin type 5 | 0.0092 | 0.0849 | 0.0849 |
Echinococcus granulosus | cyclin B | 0.0042 | 0.0237 | 0.0296 |
Toxoplasma gondii | cathepsin B | 0.0151 | 0.1574 | 0.3728 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1263 | 0.2416 |
Loa Loa (eye worm) | cathepsin B | 0.0151 | 0.1574 | 0.3011 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0034 | 0.0136 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.12 | 0.2295 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0295 | 0.037 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0079 | 0.0282 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0037 | 0.0172 | 0.033 |
Echinococcus multilocularis | cyclin B | 0.0042 | 0.0237 | 0.0237 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0021 | 0.0041 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.056 | 0.6615 | 0.6615 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0172 | 0.033 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0038 | 0.0185 | 0.0232 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0672 | 0.799 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1578 | 0.3018 |
Plasmodium vivax | vivapain-2 | 0.0037 | 0.0179 | 0.3112 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0037 | 0.0179 | 0.0933 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0172 | 0.033 |
Trichomonas vaginalis | cyclins, putative | 0.0029 | 0.0073 | 0.0242 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0185 | 0.0232 |
Trichomonas vaginalis | cyclin B, putative | 0.0042 | 0.0237 | 0.1305 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0037 | 0.0179 | 0.0276 |
Loa Loa (eye worm) | hypothetical protein | 0.0448 | 0.5227 | 1 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0036 | 0.0159 | 0.0798 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1263 | 0.2416 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0026 | 0.0036 | 0.0069 |
Onchocerca volvulus | 0.0037 | 0.0172 | 0.1365 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Loa Loa (eye worm) | ctsf protein | 0.0037 | 0.0179 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.0082 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0378 | 0.0723 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Leishmania major | cyclin | 0.0042 | 0.0237 | 0.041 |
Trichomonas vaginalis | cyclins, putative | 0.0042 | 0.0237 | 0.1305 |
Echinococcus granulosus | cysteine protease | 0.0026 | 0.0036 | 0.0045 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0295 | 0.0565 |
Onchocerca volvulus | 0.0037 | 0.0179 | 0.1421 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0037 | 0.0179 | 0.1421 |
Onchocerca volvulus | 0.0037 | 0.0179 | 0.1421 | |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0497 | 0.0951 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0295 | 0.0565 |
Echinococcus granulosus | Furin 1 | 0.0036 | 0.0159 | 0.0199 |
Brugia malayi | Trypsin family protein | 0.012 | 0.12 | 0.2295 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0042 | 0.0237 | 0.0453 |
Loa Loa (eye worm) | calpain family protein 1 | 0.006 | 0.0462 | 0.0884 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0037 | 0.0179 | 0.0933 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0185 | 0.0969 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0185 | 0.0287 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0448 | 0.5227 | 1 |
Onchocerca volvulus | 0.0037 | 0.0172 | 0.1365 | |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0026 | 0.0036 | 0.0045 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0037 | 0.0179 | 0.3112 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0172 | 0.033 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0036 | 0.0159 | 0.0798 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0179 | 0.0343 |
Loa Loa (eye worm) | fibroinase | 0.0037 | 0.0179 | 0.0343 |
Trichomonas vaginalis | cyclins, putative | 0.0042 | 0.0237 | 0.1305 |
Echinococcus granulosus | cathepsin l1 | 0.0029 | 0.0082 | 0.0102 |
Onchocerca volvulus | 0.0037 | 0.0179 | 0.1421 | |
Onchocerca volvulus | 0.0037 | 0.0172 | 0.1365 | |
Toxoplasma gondii | cathepsin CPL | 0.0037 | 0.0179 | 0.0019 |
Onchocerca volvulus | 0.0063 | 0.0497 | 0.3936 | |
Giardia lamblia | High cysteine membrane protein Group 2 | 0.0056 | 0.041 | 0.2214 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0038 | 0.0185 | 0.5 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0037 | 0.0179 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0037 | 0.0179 | 0.0225 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0151 | 0.1574 | 0.2963 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0079 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.12 | 0.2295 |
Echinococcus granulosus | neuroendocrine convertase 2 | 0.0095 | 0.0887 | 0.1111 |
Trichomonas vaginalis | cyclin B, putative | 0.0042 | 0.0237 | 0.1305 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0448 | 0.5227 | 0.6542 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0295 | 0.037 |
Loa Loa (eye worm) | endoprotease bli-4 | 0.0151 | 0.1578 | 0.3018 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Schistosoma mansoni | subfamily S8B non-peptidase homologue (S08 family) | 0.0036 | 0.0159 | 0.0199 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0038 | 0.0185 | 0.743 |
Trypanosoma cruzi | cyclin 6, putative | 0.0042 | 0.0237 | 0.0387 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.056 | 0.6615 | 0.8279 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Onchocerca volvulus | Huntingtin homolog | 0.0125 | 0.1263 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0179 | 0.0343 |
Echinococcus multilocularis | Furin 1 | 0.0036 | 0.0159 | 0.0159 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0026 | 0.0036 | 0.0045 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0082 | 0.0156 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0179 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0179 | 0.0933 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0029 | 0.0082 | 0.0102 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0079 | 0.0282 |
Onchocerca volvulus | 0.0098 | 0.092 | 0.7283 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0079 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0182 | 0.0348 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.012 | 0.12 | 0.1502 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0063 | 0.0497 | 0.0888 |
Trypanosoma cruzi | cyclin, putative | 0.0042 | 0.0237 | 0.0387 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0172 | 0.033 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0079 | 0.0282 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0042 | 0.0237 | 0.041 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Cell survival (functional) | = 2.8 % | In vitro cell growth inhibition of H520 cell line determined using Non-Radioactive Cell Proliferation Assay at a dose of 100 uM | ChEMBL. | 11392530 |
Cell survival (functional) | = 6.7 % | In vitro cell growth inhibition of PC3 cell line determined using non-radioactive cell proliferation assay at a dose of 100 uM | ChEMBL. | 11392530 |
Cell survival (functional) | = 6.7 % | In vitro cell growth inhibition of PC3 cell line determined using non-radioactive cell proliferation assay at a dose of 100 uM | ChEMBL. | 11392530 |
Cell survival (functional) | = 61.1 % | In vitro cell growth inhibition of H520 cell line determined using non-radioactive cell proliferation assay at a dose of 50 uM | ChEMBL. | 11392530 |
Cell survival (functional) | = 67.9 % | In vitro cell growth inhibition of H520 cell line determined using non-radioactive cell proliferation assay at a dose of 10 uM | ChEMBL. | 11392530 |
Cell survival (functional) | = 77 % | In vitro cell growth inhibition of PC3 cell line determined using Non-Radioactive Cell Proliferation Assay at a dose of 50 uM | ChEMBL. | 11392530 |
Cell survival (functional) | = 77 % | In vitro cell growth inhibition of PC3 cell line determined using Non-Radioactive Cell Proliferation Assay at a dose of 50 uM | ChEMBL. | 11392530 |
Cell survival (functional) | = 95.7 % | In vitro cell growth inhibition of PC3 cell line determined using non-radioactive cell proliferation assay at a dose of 10 uM | ChEMBL. | 11392530 |
Cell survival (functional) | = 95.7 % | In vitro cell growth inhibition of PC3 cell line determined using non-radioactive cell proliferation assay at a dose of 10 uM | ChEMBL. | 11392530 |
DNA relaxation (functional) | 0 | Inhibition of topo II-mediated DNA relaxation measured by topo II-mediated DNA relaxation assay | ChEMBL. | 11392530 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.