Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | melanin-concentrating hormone receptor 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Hypothetical protein | 0.0127 | 0.1056 | 0.5287 |
Echinococcus multilocularis | NAD dependent deacetylase sirtuin 3 | 0.0127 | 0.1056 | 0.1041 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.1277 | 0.6409 |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0674 | 1 | 1 |
Onchocerca volvulus | 0.0063 | 0.0016 | 0.5 | |
Echinococcus granulosus | NAD dependent deacetylase sirtuin 1 | 0.014 | 0.1277 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.1983 | 1 |
Giardia lamblia | NAD-dependent histone deacetylase Sir2 | 0.014 | 0.1277 | 0.6409 |
Echinococcus multilocularis | chromatin regulatory protein sir2 | 0.0127 | 0.1056 | 0.1041 |
Plasmodium falciparum | protein farnesyltransferase subunit alpha | 0.0183 | 0.1983 | 1 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.014 | 0.1277 | 0.6409 |
Trypanosoma cruzi | Silent information regulator 2 related protein 1 | 0.0127 | 0.1056 | 1 |
Entamoeba histolytica | Sir2 family transcriptional regulator, putative | 0.0127 | 0.1056 | 0.5287 |
Mycobacterium tuberculosis | Possible exported protein | 0.0499 | 0.7148 | 1 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.0183 | 0.1983 | 1 |
Echinococcus granulosus | NAD dependent deacetylase sirtuin 3 | 0.0127 | 0.1056 | 0.1041 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0183 | 0.1983 | 1 |
Entamoeba histolytica | protein farnesyltransferase alpha subunit, putative | 0.0183 | 0.1983 | 1 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.012 | 0.095 | 0.475 |
Echinococcus granulosus | chromatin regulatory protein sir2 | 0.0127 | 0.1056 | 0.1041 |
Plasmodium vivax | prenyltransferase alpha subunit, putative | 0.0183 | 0.1983 | 1 |
Trypanosoma cruzi | Protein prenyltransferase alpha subunit repeat, putative | 0.0063 | 0.0016 | 0.0156 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0183 | 0.1983 | 1 |
Brugia malayi | NAD-dependent deacetylase SIRT1 | 0.014 | 0.1277 | 0.6409 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0127 | 0.1056 | 0.5287 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0127 | 0.1056 | 0.5287 |
Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.0183 | 0.1983 | 1 |
Trypanosoma brucei | protein farnesyltransferase alpha subunit, putative | 0.0063 | 0.0016 | 0.0156 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0063 | 0.0016 | 0.0156 |
Trypanosoma brucei | Protein prenyltransferase alpha subunit repeat, putative | 0.0063 | 0.0016 | 0.0156 |
Trypanosoma cruzi | Silent information regulator 2 related protein 1 | 0.0127 | 0.1056 | 1 |
Echinococcus multilocularis | protein farnesyltransferase alpha subunit | 0.0183 | 0.1983 | 0.1969 |
Trypanosoma cruzi | protein farnesyltransferase alpha subunit, putative | 0.0063 | 0.0016 | 0.0156 |
Echinococcus multilocularis | NAD dependent deacetylase sirtuin 1 | 0.014 | 0.1277 | 0.1262 |
Toxoplasma gondii | hypothetical protein | 0.012 | 0.095 | 1 |
Trypanosoma cruzi | protein farnesyltransferase alpha subunit, putative | 0.0063 | 0.0016 | 0.0156 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.014 | 0.1277 | 0.6409 |
Loa Loa (eye worm) | transcriptional regulator | 0.0127 | 0.1056 | 0.5287 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.014 | 0.1277 | 0.6409 |
Giardia lamblia | Rab geranylgeranyltransferase | 0.0183 | 0.1983 | 1 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0127 | 0.1056 | 0.5287 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0127 | 0.1056 | 0.5287 |
Trypanosoma brucei | Protein prenyltransferase alpha subunit repeat, putative | 0.0063 | 0.0016 | 0.0156 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0063 | 0.0016 | 0.0156 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.014 | 0.1277 | 0.6409 |
Entamoeba histolytica | Sir2 family transcriptional regulator, putative | 0.0127 | 0.1056 | 0.5287 |
Leishmania major | silent information regulator 2, putative | 0.0127 | 0.1056 | 1 |
Brugia malayi | transcriptional regulator, Sir2 family protein | 0.0127 | 0.1056 | 0.5287 |
Trypanosoma brucei | Silent information regulator 2 related protein 1 | 0.0127 | 0.1056 | 1 |
Echinococcus granulosus | protein farnesyltransferase alpha subunit | 0.0183 | 0.1983 | 0.1969 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0127 | 0.1056 | 0.5287 |
Schistosoma mansoni | protein farnesyltransferase alpha subunit | 0.0183 | 0.1983 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0744 | 0.37 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.0183 | 0.1983 | 1 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.014 | 0.1277 | 0.6409 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0063 | 0.0016 | 0.0156 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.