Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | cyclin A1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | metabotropic glutamate receptor | 0.0128 | 0.2526 | 0.2526 |
Trichomonas vaginalis | cyclin B, putative | 0.0051 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0323 | 0.8977 | 1 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0059 | 0.0254 | 0.5 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0262 | 0.6973 | 1 |
Brugia malayi | Doublecortin family protein | 0.0059 | 0.0254 | 0.0365 |
Echinococcus multilocularis | RUN | 0.0059 | 0.0254 | 0.0254 |
Trypanosoma cruzi | cyclin 6, putative | 0.0051 | 0 | 0.5 |
Trypanosoma cruzi | cyclin, putative | 0.0051 | 0 | 0.5 |
Onchocerca volvulus | 0.0059 | 0.0254 | 1 | |
Schistosoma mansoni | rab6-interacting | 0.0059 | 0.0254 | 0.0254 |
Onchocerca volvulus | 0.0059 | 0.0254 | 1 | |
Trichomonas vaginalis | cyclin B, putative | 0.0051 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0522 | 0.0581 |
Trichomonas vaginalis | cyclins, putative | 0.0051 | 0 | 0.5 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.0067 | 0.0522 | 0.0581 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0051 | 0 | 0.5 |
Leishmania major | cyclin | 0.0051 | 0 | 0.5 |
Schistosoma mansoni | polycystin 1-related | 0.0059 | 0.0254 | 0.0254 |
Trypanosoma cruzi | cyclin, putative | 0.0051 | 0 | 0.5 |
Loa Loa (eye worm) | glutamate receptor | 0.0103 | 0.1711 | 0.1905 |
Entamoeba histolytica | cyclin, putative | 0.0051 | 0 | 0.5 |
Schistosoma mansoni | lipoxygenase | 0.0247 | 0.6479 | 0.6479 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0059 | 0.0254 | 0.5 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0051 | 0 | 0.5 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0323 | 0.8977 | 0.8977 |
Trichomonas vaginalis | cyclins, putative | 0.0051 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0059 | 0.0254 | 0.0365 |
Schistosoma mansoni | hypothetical protein | 0.0059 | 0.0254 | 0.0254 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0323 | 0.8977 | 0.8977 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0059 | 0.0254 | 0.0254 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0254 | 0.0283 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0059 | 0.0254 | 0.0254 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.022 | 0.5565 | 0.5565 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0067 | 0.0522 | 0.0748 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0354 | 1 | 1 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.022 | 0.5565 | 0.5565 |
Schistosoma mansoni | loxhd1 | 0.0059 | 0.0254 | 0.0254 |
Schistosoma mansoni | rab6-interacting | 0.0059 | 0.0254 | 0.0254 |
Trichomonas vaginalis | cyclin B, putative | 0.0051 | 0 | 0.5 |
Loa Loa (eye worm) | glutamate receptor | 0.0262 | 0.6973 | 0.7767 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0059 | 0.0254 | 0.0254 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0059 | 0.0254 | 0.0254 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0059 | 0.0254 | 0.0254 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.022 | 0.5565 | 0.5565 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0059 | 0.0254 | 0.0254 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0051 | 0 | 0.5 |
Trichomonas vaginalis | cyclin B, putative | 0.0051 | 0 | 0.5 |
Echinococcus granulosus | RUN | 0.0059 | 0.0254 | 0.0254 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0237 | 0.6157 | 0.883 |
Trichomonas vaginalis | cyclins, putative | 0.0051 | 0 | 0.5 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0051 | 0 | 0.5 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0128 | 0.2526 | 0.3623 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.0067 | 0.0522 | 0.0581 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0254 | 0.0283 |
Trichomonas vaginalis | cyclin A, putative | 0.0051 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0059 | 0.0254 | 0.0365 |
Loa Loa (eye worm) | doublecortin family protein | 0.0059 | 0.0254 | 0.0283 |
Schistosoma mansoni | lipoxygenase | 0.0354 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0051 | 0 | 0.5 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0298 | 0.8162 | 0.8162 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.