Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | FK506 binding protein 1A, 12kDa | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target | Length | Alignment span | Identity |
---|---|---|---|---|---|
Trypanosoma brucei | macrophage infectivity potentiator, precursor, putative | FK506 binding protein 1A, 12kDa | 108 aa | 107 aa | 48.6 % |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Chlamydia trachomatis | peptidyl-prolyl cis-trans isomerase | 0.0009 | 0 | 0.5 |
Echinococcus multilocularis | plexin a4 | 0.0024 | 0.2633 | 0.2633 |
Schistosoma mansoni | immunophilin | 0.0056 | 0.8404 | 0.8404 |
Schistosoma mansoni | plexin | 0.0012 | 0.0485 | 0.0485 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP1A | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-12 | 0.0065 | 1 | 1 |
Schistosoma mansoni | plexin | 0.002 | 0.1979 | 0.1979 |
Trichomonas vaginalis | immunophilin, putative | 0.0065 | 1 | 1 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.0065 | 1 | 1 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.0065 | 1 | 1 |
Trypanosoma brucei | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.0065 | 1 | 1 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.0009 | 0 | 0.5 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.0065 | 1 | 1 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.0056 | 0.8404 | 0.8404 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type , putative | 0.0065 | 1 | 1 |
Mycobacterium leprae | PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG | 0.0009 | 0 | 0.5 |
Plasmodium falciparum | peptidyl-prolyl cis-trans isomerase FKBP35 | 0.0065 | 1 | 1 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.0065 | 1 | 1 |
Brugia malayi | plexin A | 0.0024 | 0.2633 | 0.2633 |
Treponema pallidum | peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) | 0.0065 | 1 | 1 |
Echinococcus multilocularis | fk506 binding protein | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1979 | 0.1979 |
Schistosoma mansoni | immunophilin | 0.0065 | 1 | 1 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type, putative | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | plexin A | 0.0024 | 0.2633 | 0.2633 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.0065 | 1 | 1 |
Leishmania major | fk506-binding protein 1-like protein | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0485 | 0.0485 |
Loa Loa (eye worm) | FKBP5 protein | 0.0065 | 1 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.0065 | 1 | 1 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.0056 | 0.8404 | 0.8404 |
Leishmania major | peptidylprolyl isomerase-like protein | 0.0065 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | FKBP-type peptidylprolyl isomerase | 0.0009 | 0 | 0.5 |
Toxoplasma gondii | peptidyl-prolyl isomerase FKBP12, putative | 0.0009 | 0 | 0.5 |
Schistosoma mansoni | immunophilin FK506 binding protein FKBP12 | 0.0065 | 1 | 1 |
Onchocerca volvulus | 0.002 | 0.1979 | 1 | |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.0009 | 0 | 0.5 |
Mycobacterium ulcerans | FK-506 binding protein, peptidyl-prolyl cis-trans isomerase | 0.0065 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | FKBP-type peptidylprolyl isomerase | 0.0009 | 0 | 0.5 |
Echinococcus granulosus | plexin a4 | 0.0024 | 0.2633 | 0.2633 |
Mycobacterium tuberculosis | Probable trigger factor (TF) protein Tig | 0.0009 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0485 | 0.0485 |
Giardia lamblia | 70 kDa peptidylprolyl isomerase, putative | 0.0065 | 1 | 1 |
Plasmodium vivax | 70 kDa peptidylprolyl isomerase, putative | 0.0065 | 1 | 1 |
Giardia lamblia | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.0065 | 1 | 1 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase, putative | 0.0065 | 1 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.0065 | 1 | 1 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 | 0.0065 | 1 | 1 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.0065 | 1 | 1 |
Schistosoma mansoni | immunophilin | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.8404 | 0.8404 |
Brugia malayi | Plexin repeat family protein | 0.002 | 0.1979 | 0.1979 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.0009 | 0 | 0.5 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.0065 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.