Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | phosphoenolpyruvate carboxykinase 1 (soluble) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Phosphoenolpyruvate carboxykinase | 0.0088 | 0.0259 | 0.5 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.1532 | 1 | 1 |
Echinococcus multilocularis | sn1 specific diacylglycerol lipase beta | 0.0707 | 0.4436 | 0.4288 |
Mycobacterium ulcerans | amidase | 0.0185 | 0.0911 | 1 |
Plasmodium vivax | glutamyl-tRNA(Gln) amidotransferase subunit A, putative | 0.0185 | 0.0911 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0707 | 0.4436 | 1 |
Mycobacterium tuberculosis | Probable amidase AmiB2 (aminohydrolase) | 0.0185 | 0.0911 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1532 | 1 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.1532 | 1 | 1 |
Loa Loa (eye worm) | amidase | 0.0185 | 0.0911 | 0.067 |
Schistosoma mansoni | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0185 | 0.0911 | 0.067 |
Brugia malayi | Amidase family protein | 0.0185 | 0.0911 | 0.067 |
Mycobacterium ulcerans | amidase | 0.0185 | 0.0911 | 1 |
Trypanosoma brucei | lipase domain protein, putative | 0.0707 | 0.4436 | 1 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0185 | 0.0911 | 0.067 |
Schistosoma mansoni | amidase | 0.1532 | 1 | 1 |
Mycobacterium leprae | PROBABLE AMIDASE AMIC (AMINOHYDROLASE) | 0.0185 | 0.0911 | 1 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.1532 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0707 | 0.4436 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0707 | 0.4436 | 1 |
Mycobacterium ulcerans | amidase | 0.0185 | 0.0911 | 1 |
Trichomonas vaginalis | phosphoenolpyruvate carboxykinase, putative | 0.0088 | 0.0259 | 0.0583 |
Onchocerca volvulus | 0.0707 | 0.4436 | 1 | |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0185 | 0.0911 | 0.067 |
Mycobacterium ulcerans | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0185 | 0.0911 | 1 |
Trichomonas vaginalis | lipase containing protein, putative | 0.0707 | 0.4436 | 1 |
Mycobacterium leprae | PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) | 0.0185 | 0.0911 | 1 |
Plasmodium falciparum | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0185 | 0.0911 | 0.5 |
Echinococcus granulosus | glutamyl tRNAGln amidotransferase subunit A | 0.0185 | 0.0911 | 0.067 |
Trichomonas vaginalis | phosphoenolpyruvate carboxykinase, putative | 0.0068 | 0.0126 | 0.0283 |
Trichomonas vaginalis | phosphoenolpyruvate carboxykinase, putative | 0.0088 | 0.0259 | 0.0583 |
Mycobacterium tuberculosis | Possible amidase (aminohydrolase) | 0.0185 | 0.0911 | 1 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0185 | 0.0911 | 1 |
Loa Loa (eye worm) | lipase | 0.0707 | 0.4436 | 0.4288 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0159 | 0.0741 | 0.7384 |
Loa Loa (eye worm) | amidase | 0.0185 | 0.0911 | 0.067 |
Mycobacterium tuberculosis | Probable amidase AmiD (acylamidase) (acylase) | 0.0185 | 0.0911 | 1 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0185 | 0.0911 | 1 |
Brugia malayi | putative amidase | 0.0185 | 0.0911 | 0.067 |
Mycobacterium tuberculosis | Probable amidase AmiC (aminohydrolase) | 0.0185 | 0.0911 | 1 |
Brugia malayi | Lipase family protein | 0.0707 | 0.4436 | 0.4288 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.1532 | 1 | 1 |
Mycobacterium ulcerans | peptide amidase, GatA | 0.0185 | 0.0911 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0159 | 0.0741 | 0.7384 |
Mycobacterium ulcerans | amidase | 0.0185 | 0.0911 | 1 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0185 | 0.0911 | 0.5 |
Brugia malayi | Amidase family protein | 0.0185 | 0.0911 | 0.067 |
Trichomonas vaginalis | phosphoenolpyruvate carboxykinase, putative | 0.0088 | 0.0259 | 0.0583 |
Mycobacterium ulcerans | amidase | 0.0185 | 0.0911 | 1 |
Mycobacterium tuberculosis | Probable amidase AmiA2 (aminohydrolase) | 0.0185 | 0.0911 | 1 |
Trichomonas vaginalis | phosphoenolpyruvate carboxykinase, putative | 0.0088 | 0.0259 | 0.0583 |
Echinococcus multilocularis | glutamyl tRNA(Gln) amidotransferase subunit A | 0.0185 | 0.0911 | 0.067 |
Trichomonas vaginalis | lipase containing protein, putative | 0.0707 | 0.4436 | 1 |
Echinococcus granulosus | sn1 specific diacylglycerol lipase beta | 0.0707 | 0.4436 | 0.4288 |
Trypanosoma brucei | lipase domain protein, putative | 0.0707 | 0.4436 | 1 |
Trichomonas vaginalis | phosphoenolpyruvate carboxykinase, putative | 0.0088 | 0.0259 | 0.0583 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.1532 | 1 | 1 |
Trichomonas vaginalis | phosphoenolpyruvate carboxykinase, putative | 0.0068 | 0.0126 | 0.0283 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0185 | 0.0911 | 0.067 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.