TDR Targets

Basic information

Technical information

TDR Targets ID: 442390
Name: 2-[6-[[5-(4-chlorophenyl)-1,2-oxazol-3-yl]met hoxy]-5-methyl-1-benzothiophen-3-yl]acetic ac id
MW: 413.874 | Formula: C21H16ClNO4S
H donors: 1 H acceptors: 3 LogP: 5.01 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: OC(=O)Cc1csc2c1cc(C)c(c2)OCc1noc(c1)c1ccc(cc1)Cl
InChi: 1S/C21H16ClNO4S/c1-12-6-17-14(7-21(24)25)11-28-20(17)9-18(12)26-10-16-8-19(27-23-16)13-2-4-15(22)5-3-13/h2-6,8-9,11H,7,10H2,1H3,(H,24,25)
InChiKey: ZVKBDHBUPHRNRS-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

2-[6-[[5-(4-chlorophenyl)isoxazol-3-yl]methoxy]-5-methyl-benzothiophen-3-yl]acetic acid
2-[6-[[5-(4-chlorophenyl)-3-isoxazolyl]methoxy]-5-methyl-3-benzothiophenyl]acetic acid
2-[6-[[5-(4-chlorophenyl)-1,2-oxazol-3-yl]methoxy]-5-methyl-1-benzothiophen-3-yl]ethanoic acid

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	peroxisome proliferator-activated receptor alpha	Starlite/ChEMBL	References
Homo sapiens	peroxisome proliferator-activated receptor delta	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Schistosoma japonicum	ko:K08701 nuclear receptor, subfamily 1, invertebrate, putative	Get druggable targets OG5_137778	All targets in OG5_137778
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	Get druggable targets OG5_137778	All targets in OG5_137778
Schistosoma japonicum	IPR008946,Nuclear receptor, ligand-binding,domain-containing	Get druggable targets OG5_137778	All targets in OG5_137778

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Brugia malayi	ecdysteroid receptor	peroxisome proliferator-activated receptor alpha	468 aa	397 aa	25.4 %
Brugia malayi	ecdysteroid receptor	peroxisome proliferator-activated receptor delta	441 aa	369 aa	24.7 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	hypothetical protein	0.014	0.1085	0.1085
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0024	0.0092	0.0092
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0024	0.0092	0.0092
Trichomonas vaginalis	AGC family protein kinase	0.0709	0.599	1
Brugia malayi	ecdysteroid receptor	0.0024	0.0092	0.0092
Echinococcus multilocularis	FTZ F1 alpha	0.0024	0.0092	0.0195
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0024	0.0092	0.0092
Echinococcus granulosus	FTZ F1 alpha	0.0024	0.0092	0.0195
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0024	0.0092	0.0092
Echinococcus granulosus	protein kinase c epsilon type	0.0246	0.2	0.4216
Brugia malayi	Nuclear hormone receptor-like 1	0.0024	0.0092	0.0092
Schistosoma mansoni	serine/threonine kinase	0.0246	0.2	0.4216
Onchocerca volvulus		0.014	0.1085	1
Echinococcus multilocularis	Protein kinase C, brain isozyme	0.0246	0.2	0.4216
Onchocerca volvulus	Bile acid receptor homolog	0.0024	0.0092	0.0852
Echinococcus multilocularis	nervana 2	0.0462	0.3856	0.8129
Brugia malayi	Steroid receptor seven-up type 2	0.0024	0.0092	0.0092
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0024	0.0092	0.0195
Echinococcus multilocularis	ribosomal protein S6 kinase alpha 3	0.0246	0.2	0.4216
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0024	0.0092	0.0195
Entamoeba histolytica	protein kinase, putative	0.0565	0.4743	0.7918
Toxoplasma gondii	AGC kinase	0.0707	0.5973	1
Schistosoma mansoni	serine/threonine-protein kinase	0.0474	0.3963	0.8356
Schistosoma mansoni	hypothetical protein	0.014	0.1085	0.2287
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0019	0.0048	0.01
Brugia malayi	Protein kinase domain containing protein	0.0709	0.599	0.599
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0024	0.0092	0.0195
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0092	0.0092
Trichomonas vaginalis	AGC family protein kinase	0.0709	0.599	1
Trichomonas vaginalis	AGC family protein kinase	0.0565	0.4743	0.6944
Brugia malayi	Hr1 repeat family protein	0.0246	0.2	0.2
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0092	0.0092
Echinococcus multilocularis	serine threonine protein kinase	0.0246	0.2	0.4216
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0024	0.0092	0.0092
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0024	0.0092	0.0195
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0024	0.0092	0.0195
Entamoeba histolytica	protein kinase, putative	0.0709	0.599	1
Schistosoma mansoni	coup transcription factor	0.0024	0.0092	0.0195
Loa Loa (eye worm)	hypothetical protein	0.0246	0.2	0.2
Echinococcus granulosus	serine:threonine protein kinase N2	0.0246	0.2	0.4216
Entamoeba histolytica	protein kinase 2, putative	0.0472	0.3946	0.6588
Loa Loa (eye worm)	AGC/RSK/P70 protein kinase	0.0707	0.5973	0.5975
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0024	0.0092	0.0195
Loa Loa (eye worm)	AGC/RSK/MSK protein kinase	0.0246	0.2	0.2
Echinococcus granulosus	Glutaredoxin protein 5	0.0462	0.3856	0.8129
Trichomonas vaginalis	AGC family protein kinase	0.0246	0.2	0.0221
Loa Loa (eye worm)	hypothetical protein	0.014	0.1085	0.1085
Loa Loa (eye worm)	AGC/PDK1 protein kinase	0.0565	0.4743	0.4745
Echinococcus granulosus	3-phosphoinositide-dependent protein kinase 1	0.0565	0.4743	1
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0024	0.0092	0.0092
Plasmodium falciparum	RAC-beta serine/threonine protein kinase	0.0472	0.3946	1
Brugia malayi	Protein kinase domain containing protein	0.0246	0.2	0.2
Trichomonas vaginalis	AGC family protein kinase	0.0248	0.2017	0.0263
Echinococcus granulosus	activin receptor type	0.0019	0.0048	0.01
Plasmodium vivax	rac-beta serine/threonine protein kinase, putative	0.0472	0.3946	0.5
Echinococcus granulosus	Ribosomal protein S6 kinase beta 2	0.0246	0.2	0.4216
Trichomonas vaginalis	AGC family protein kinase	0.0565	0.4743	0.6944
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0024	0.0092	0.0092
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0024	0.0092	0.0092
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.0428	0.3569	0.7524
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0024	0.0092	0.0092
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0024	0.0092	0.0092
Loa Loa (eye worm)	AGC/NDR protein kinase	0.0246	0.2	0.2
Onchocerca volvulus		0.0024	0.0092	0.0852
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0024	0.0092	0.0195
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0092	0.0092
Echinococcus granulosus	protein kinase c iota type	0.0246	0.2	0.4216
Brugia malayi	nuclear receptor NHR-88	0.0024	0.0092	0.0092
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0024	0.0092	0.0195
Echinococcus multilocularis	ecdysone induced protein 78C	0.0024	0.0092	0.0195
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0024	0.0092	0.0092
Loa Loa (eye worm)	AGC/PKN protein kinase	0.0246	0.2	0.2
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0024	0.0092	0.0092
Brugia malayi	steroid hormone receptor	0.0024	0.0092	0.0092
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0024	0.0092	0.0195
Echinococcus granulosus	serine threonine protein kinase nrc	0.0472	0.3946	0.832
Schistosoma mansoni	serine/threonine protein kinase	0.0246	0.2	0.4216
Trichomonas vaginalis	AGC family protein kinase	0.0709	0.599	1
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0092	0.0092
Trichomonas vaginalis	AGC family protein kinase	0.0709	0.599	1
Echinococcus granulosus	nervana 2	0.0462	0.3856	0.8129
Entamoeba histolytica	protein kinase domain containing protein	0.0019	0.0048	0.0079
Schistosoma mansoni	serine/threonine protein kinase	0.0246	0.2	0.4216
Onchocerca volvulus		0.014	0.1085	1
Schistosoma mansoni	serine/threonine protein kinase	0.0246	0.2	0.4216
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0024	0.009	0.019
Schistosoma mansoni	serine/threonine protein kinase	0.0565	0.4743	1
Leishmania major	protein kinase, putative	0.0019	0.0048	0.5
Echinococcus multilocularis	Ribosomal protein S6 kinase beta 2	0.0246	0.2	0.4216
Loa Loa (eye worm)	TK/ALK protein kinase	0.1175	0.9997	1
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0024	0.0092	0.0195
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0092	0.0092
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0024	0.0092	0.0092
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0024	0.0092	0.0195
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.0472	0.3946	0.9956
Schistosoma mansoni	serine/threonine protein kinase	0.0246	0.2	0.4216
Schistosoma mansoni	nuclear hormone receptor	0.0024	0.0092	0.0195
Echinococcus granulosus	MAM	0.014	0.1085	0.2287
Echinococcus multilocularis	nervana 2	0.0462	0.3856	0.8129
Entamoeba histolytica	protein kinase, putative	0.0015	0.0015	0.0025
Schistosoma mansoni	RAR-like nuclear receptor	0.0024	0.0092	0.0195
Brugia malayi	p70 ribosomal S6 kinase beta	0.0707	0.5973	0.5973
Entamoeba histolytica	protein kinase, putative	0.0709	0.599	1
Trichomonas vaginalis	AGC family protein kinase	0.0709	0.599	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0024	0.0092	0.0092
Echinococcus multilocularis	Glutaredoxin protein 5	0.0462	0.3856	0.8129
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0024	0.0092	0.0195
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0474	0.3963	0.6616
Schistosoma mansoni	thyroid hormone receptor	0.0024	0.0092	0.0195
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0024	0.0092	0.0195
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0015	0.0015	0.0025
Echinococcus multilocularis	3 phosphoinositide dependent protein kinase 1	0.0565	0.4743	1
Loa Loa (eye worm)	AGC/PDK1 protein kinase	0.0565	0.4743	0.4745
Echinococcus granulosus	ribosomal protein s6 kinase beta 1	0.0246	0.2	0.4216
Echinococcus granulosus	NDR protein kinase	0.0246	0.2	0.4216
Loa Loa (eye worm)	AGC/RSK/RSK protein kinase	0.0246	0.2	0.2
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0019	0.0048	0.01
Schistosoma mansoni	serine/threonine protein kinase	0.0246	0.2	0.4216
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0024	0.0092	0.0195
Brugia malayi	protein kinase C II.	0.0246	0.2	0.2
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0024	0.0092	0.0195
Brugia malayi	nuclear hormone receptor	0.0024	0.0092	0.0092
Giardia lamblia	Kinase, AGC PKA	0.0472	0.3946	0.5
Loa Loa (eye worm)	hypothetical protein	0.014	0.1085	0.1085
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0024	0.0092	0.0195
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0024	0.0092	0.0092
Brugia malayi	Protein kinase domain containing protein	0.0565	0.4743	0.4743
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0474	0.3963	0.6616
Schistosoma mansoni	serine/threonine protein kinase	0.0246	0.2	0.4216
Brugia malayi	photoreceptor-specific nuclear receptor	0.0024	0.0092	0.0092
Echinococcus granulosus	protein kinase C gamma type	0.0246	0.2	0.4216
Echinococcus multilocularis	rac serine:threonine kinase	0.0474	0.3963	0.8356
Schistosoma mansoni	thyroid hormone receptor	0.0024	0.0092	0.0195
Loa Loa (eye worm)	hypothetical protein	0.1026	0.8719	0.8722
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0024	0.0092	0.0195
Echinococcus granulosus	ribosomal protein S6 kinase alpha 3	0.0246	0.2	0.4216
Trichomonas vaginalis	AGC family protein kinase	0.0709	0.599	1
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0092	0.0092
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0024	0.0092	0.0195
Schistosoma mansoni	protein kinase	0.0019	0.0048	0.01
Loa Loa (eye worm)	AGC/PKC/ETA protein kinase	0.0246	0.2	0.2
Echinococcus multilocularis	serine threonine protein kinase nrc serine threonine protein kinase gad	0.0472	0.3946	0.832
Echinococcus multilocularis	activin receptor type	0.0019	0.0048	0.01
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0024	0.0092	0.0195
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0024	0.0092	0.0195
Trichomonas vaginalis	AGC family protein kinase	0.0709	0.599	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0024	0.0092	0.0092
Schistosoma mansoni	serine/threonine protein kinase	0.0246	0.2	0.4216
Echinococcus multilocularis	serine:threonine protein kinase N2	0.0246	0.2	0.4216
Brugia malayi	phosphoinositide-dependent protein kinase I	0.0565	0.4743	0.4743
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0024	0.0092	0.0852
Echinococcus multilocularis	MAM	0.014	0.1085	0.2287
Schistosoma mansoni	hypothetical protein	0.014	0.1085	0.2287
Echinococcus granulosus	nervana 2	0.0462	0.3856	0.8129
Echinococcus granulosus	serine/threonine protein kinase	0.0474	0.3963	0.8356
Entamoeba histolytica	protein kinase, putative	0.0246	0.2	0.3338
Trypanosoma cruzi	Protein kinase B	0.0474	0.3963	1
Loa Loa (eye worm)	AGC/DMPK/GEK protein kinase	0.0246	0.2	0.2
Schistosoma mansoni	protein kinase	0.0019	0.0048	0.01
Echinococcus multilocularis	protein kinase c epsilon type	0.0246	0.2	0.4216
Echinococcus multilocularis	serine:threonine protein kinase 38	0.0246	0.2	0.4216
Trichomonas vaginalis	AGC family protein kinase	0.0246	0.2	0.0221
Schistosoma mansoni	atypical protein kinase C	0.0246	0.2	0.4216
Entamoeba histolytica	protein kinase, putative	0.0707	0.5973	0.9971
Onchocerca volvulus	Protein ultraspiracle homolog	0.0024	0.0092	0.0852
Echinococcus granulosus	calcium:calmodulin dependent protein kinase	0.0472	0.3946	0.832
Echinococcus granulosus	sodium:potassium dependent atpase beta subunit	0.0462	0.3856	0.8129
Trypanosoma brucei	rac serine-threonine kinase, putative	0.0709	0.599	1
Brugia malayi	Protein kinase domain containing protein	0.0246	0.2	0.2
Schistosoma mansoni	protein kinase	0.0019	0.0048	0.01
Echinococcus multilocularis	ribosomal protein s6 kinase beta 1	0.0246	0.2	0.4216
Loa Loa (eye worm)	hypothetical protein	0.014	0.1085	0.1085
Schistosoma mansoni	retinoic acid receptor RXR	0.0024	0.0092	0.0195
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0092	0.0092
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.0474	0.3963	1
Trichomonas vaginalis	AGC family protein kinase	0.0246	0.2	0.0221
Trichomonas vaginalis	AGC family protein kinase	0.0565	0.4743	0.6944
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0092	0.0092
Echinococcus multilocularis	serine:threonine protein kinase N2	0.0246	0.2	0.4216
Loa Loa (eye worm)	AGC/AKT protein kinase	0.0709	0.599	0.5992
Echinococcus multilocularis	sodium:potassium dependent atpase beta subunit	0.0462	0.3856	0.8129
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0024	0.0092	0.0092
Echinococcus granulosus	ecdysone induced protein 78C	0.0024	0.0092	0.0195
Schistosoma mansoni	serine/threonine-protein kinase	0.0474	0.3963	0.8356
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0024	0.0092	0.0092
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0024	0.0092	0.0092
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0024	0.0092	0.0195
Loa Loa (eye worm)	steroid hormone receptor	0.0024	0.0092	0.0092
Echinococcus multilocularis	protein kinase c iota type	0.0246	0.2	0.4216
Echinococcus granulosus	Protein kinase C brain isozyme	0.0246	0.2	0.4216
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0024	0.0092	0.0092

Activities

Activity type	Activity value	Assay description	Source	Reference
EC50 (functional)	= 656 nM	Agonist activity at human PPARdelta in HepG2 cells by GAL4-luciferase reporter gene assay	ChEMBL.	17512197
EC50 (functional)	= 656 nM	Agonist activity at human PPARdelta in HepG2 cells by GAL4-luciferase reporter gene assay	ChEMBL.	17512197
IC50 (binding)		Displacement of [3H]5-(4-(3-(5-methyl-2-phenyloxazol-4-yl)propanoyl)benzyl)thiazolidine-2,4-dione from human PPARgamma after 2 hrs by SPA	ChEMBL.	17512197
IC50 (binding)	0	Displacement of [3H]5-(4-(3-(5-methyl-2-phenyloxazol-4-yl)propanoyl)benzyl)thiazolidine-2,4-dione from human PPARgamma after 2 hrs by SPA	ChEMBL.	17512197
IC50 (binding)	= 37 nM	Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA	ChEMBL.	17512197
IC50 (binding)	= 37 nM	Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA	ChEMBL.	17512197
IC50 (binding)	= 5810 nM	Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPA	ChEMBL.	17512197
IC50 (binding)	= 5810 nM	Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPA	ChEMBL.	17512197
Ratio IC50 (binding)	= 159	Selectivity for human PPARdelta over human PPARalpha	ChEMBL.	17512197

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL234170
PubChem: 22504843

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 442390