TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 451.559 | Formula: C29H29N3O2
H donors: 0 H acceptors: 3 LogP: 5.62 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: CC(CCn1c(CN2C(=O)C(Cc3ccccc3)C(=O)c3c2cccc3)nc2c1cccc2)C
InChi: 1S/C29H29N3O2/c1-20(2)16-17-31-26-15-9-7-13-24(26)30-27(31)19-32-25-14-8-6-12-22(25)28(33)23(29(32)34)18-21-10-4-3-5-11-21/h3-15,20,23H,16-19H2,1-2H3
InChiKey: UHOIBFDUKQXRIN-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0318	0.0318
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0043	0.006
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0102	0.0585	0.0823
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0102	0.0585	0.0823
Leishmania major	flap endonuclease-1 (FEN-1), putative	0.0026	0.0049	0.0068
Giardia lamblia	Flap structure-specific endonuclease	0.0026	0.0049	1
Trypanosoma cruzi	PAB1-binding protein , putative	0.0026	0.0043	0.006
Brugia malayi	Nuclear hormone receptor E75	0.0048	0.0202	0.0285
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0202	0.0285
Schistosoma mansoni	hypothetical protein	0.0036	0.012	0.012
Brugia malayi	ecdysteroid receptor	0.0102	0.0585	0.0823
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0102	0.0585	0.0585
Brugia malayi	Nuclear hormone receptor-like 1	0.0102	0.0585	0.0823
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0243	0.0342
Echinococcus granulosus	tyrosyl DNA phosphodiesterase 1	0.1017	0.7105	0.7105
Brugia malayi	hypothetical protein	0.0048	0.0202	0.0285
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0191	0.0198
Schistosoma mansoni	transcription factor LCR-F1	0.0036	0.012	0.012
Brugia malayi	ImpB/MucB/SamB family protein	0.0045	0.0184	0.0258
Echinococcus multilocularis	geminin	0.0172	0.1082	0.1126
Brugia malayi	nuclear receptor NHR-88	0.0048	0.0202	0.0285
Loa Loa (eye worm)	hypothetical protein	0.0102	0.0585	0.0823
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0191	0.0191
Loa Loa (eye worm)	nuclear hormone receptor	0.0048	0.0202	0.0285
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0102	0.0585	0.0608
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0054	0.0243	0.0243
Plasmodium vivax	flap endonuclease 1, putative	0.0026	0.0049	1
Schistosoma mansoni	tyrosyl-DNA phosphodiesterase	0.1017	0.7105	0.7105
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0102	0.0585	0.0585
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0102	0.0585	0.0823
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0102	0.0585	0.0608
Mycobacterium tuberculosis	Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed))	0.002	0	0.5
Schistosoma mansoni	DNA polymerase eta	0.0045	0.0184	0.0184
Schistosoma mansoni	coup transcription factor	0.0102	0.0585	0.0585
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0191	0.0198
Echinococcus multilocularis	dna polymerase eta	0.0045	0.0184	0.0191
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0243	0.0342
Echinococcus granulosus	geminin	0.0172	0.1082	0.1082
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0102	0.0585	0.0823
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0048	0.0202	0.0202
Echinococcus granulosus	FTZ F1 alpha	0.0102	0.0585	0.0585
Echinococcus multilocularis	nuclear receptor nhr 48	0.0048	0.0202	0.021
Toxoplasma gondii	flap structure-specific endonuclease 1, putative	0.0026	0.0049	0.1335
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0318	0.0318
Entamoeba histolytica	Flap nuclease, putative	0.0026	0.0049	0.0068
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0054	0.0243	0.0243
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0102	0.0585	0.0608
Echinococcus multilocularis	tyrosyl DNA phosphodiesterase 1	0.1017	0.7105	0.7388
Schistosoma mansoni	nuclear hormone receptor	0.0102	0.0585	0.0585
Schistosoma mansoni	nuclear receptor nhr-48	0.0048	0.0202	0.0202
Brugia malayi	Flap endonuclease-1	0.0026	0.0049	0.0068
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.0048	0.0202	0.0285
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0102	0.0585	0.0585
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0191	0.0191
Brugia malayi	hypothetical protein	0.0026	0.0043	0.006
Echinococcus multilocularis	ecdysone induced protein 78C	0.0102	0.0585	0.0608
Brugia malayi	RNA recognition motif domain containing protein	0.0064	0.0318	0.0447
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.0048	0.0202	0.0285
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0102	0.0585	0.0585
Trypanosoma cruzi	flap endonuclease-1 (FEN-1), putative	0.0026	0.0049	0.0068
Echinococcus granulosus	transcription factor Dp 1	0.0589	0.4054	0.4054
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0184	0.0258
Trypanosoma cruzi	DNA polymerase eta, putative	0.0032	0.0088	0.0123
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0243	0.0342
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0102	0.0585	0.0608
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0102	0.0585	0.0608
Schistosoma mansoni	nuclear hormone receptor	0.0048	0.0202	0.0202
Trypanosoma brucei	DNA polymerase eta, putative	0.0045	0.0184	0.0258
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0102	0.0585	0.0823
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0202	0.0285
Brugia malayi	conserved hypotetical protein	0.0048	0.0202	0.0285
Echinococcus granulosus	ecdysone induced protein 78C	0.0102	0.0585	0.0585
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0048	0.0202	0.0202
Brugia malayi	nuclear receptor NHR-67	0.0048	0.0202	0.0285
Onchocerca volvulus	Bile acid receptor homolog	0.0102	0.0585	1
Schistosoma mansoni	flap endonuclease-1	0.0024	0.0031	0.0031
Schistosoma mansoni	retinoic acid receptor RXR	0.1424	1	1
Trypanosoma cruzi	DNA polymerase eta, putative	0.0045	0.0184	0.0258
Brugia malayi	hypothetical protein	0.0036	0.012	0.0169
Schistosoma mansoni	nuclear receptor	0.0048	0.0202	0.0202
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0202	0.0285
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0102	0.0585	0.0823
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.1017	0.7105	1
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0318	0.0318
Echinococcus multilocularis	flap endonuclease 1	0.0026	0.0049	0.0051
Schistosoma mansoni	hypothetical protein	0.0172	0.1082	0.1082
Trypanosoma brucei	flap endonuclease-1 (FEN-1), putative	0.0026	0.0049	0.0068
Echinococcus granulosus	nuclear receptor nhr 48	0.0048	0.0202	0.0202
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.0048	0.0202	0.0202
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0102	0.0585	0.0585
Loa Loa (eye worm)	tyrosyl-DNA phosphodiesterase	0.1017	0.7105	1
Brugia malayi	tailless protein	0.0048	0.0202	0.0285
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0102	0.0585	0.0823
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0054	0.0243	0.0243
Brugia malayi	photoreceptor-specific nuclear receptor	0.0102	0.0585	0.0823
Toxoplasma gondii	ImpB/MucB/SamB family protein	0.0032	0.0088	1
Loa Loa (eye worm)	hypothetical protein	0.0102	0.0585	0.0823
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.0048	0.0202	0.0202
Loa Loa (eye worm)	RNA binding protein	0.0064	0.0318	0.0447
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0102	0.0585	0.0585
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0102	0.0585	1
Loa Loa (eye worm)	hypothetical protein	0.0102	0.0585	0.0823
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0202	0.0285
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0318	0.0318
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0046	0.0191	0.0268
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0202	0.0285
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0202	0.0285
Schistosoma mansoni	hypothetical protein	0.0172	0.1082	0.1082
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0102	0.0585	0.0585
Brugia malayi	RNA binding protein	0.0064	0.0318	0.0447
Loa Loa (eye worm)	hypothetical protein	0.0102	0.0585	0.0823
Schistosoma mansoni	thyroid hormone receptor	0.0102	0.0585	0.0585
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0102	0.0585	0.0823
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0202	0.0285
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0102	0.0585	0.0823
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0202	0.0285
Brugia malayi	nuclear hormone receptor family member odr-7	0.0048	0.0202	0.0285
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0102	0.0585	0.0823
Trypanosoma brucei	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.1017	0.7105	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0102	0.0585	0.0823
Plasmodium falciparum	flap endonuclease 1	0.0026	0.0049	1
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0202	0.0285
Schistosoma mansoni	thyroid hormone receptor	0.0102	0.0585	0.0585
Leishmania major	tyrosyl-DNA phosphodiesterase 1	0.1017	0.7105	1
Leishmania major	DNA polymerase eta, putative	0.0045	0.0184	0.0258
Trypanosoma cruzi	PAB1-binding protein , putative	0.0026	0.0043	0.006
Echinococcus multilocularis	tar DNA binding protein	0.0064	0.0318	0.033
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.1017	0.7105	1
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0102	0.0585	0.0823
Loa Loa (eye worm)	hypothetical protein	0.0102	0.0585	0.0823
Entamoeba histolytica	hypothetical protein	0.0036	0.012	0.0169
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0102	0.0585	0.0585
Onchocerca volvulus	Protein ultraspiracle homolog	0.0102	0.0585	1
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0048	0.0202	0.021
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.0048	0.0202	0.0202
Brugia malayi	steroid hormone receptor	0.0102	0.0585	0.0823
Schistosoma mansoni	zinc finger protein	0.0048	0.0202	0.0202
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0046	0.0191	0.0268
Brugia malayi	nuclear receptor RXR	0.0048	0.0202	0.0285
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0036	0.012	0.0125
Entamoeba histolytica	hypothetical protein	0.0036	0.012	0.0169
Echinococcus granulosus	dna polymerase eta	0.0045	0.0184	0.0184
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0054	0.0243	0.0342
Brugia malayi	Nuclear hormone receptor-like 1	0.0054	0.0243	0.0342
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0191	0.0191
Echinococcus granulosus	thyroid hormone receptor alpha	0.0048	0.0202	0.0202
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0102	0.0585	0.0585
Entamoeba histolytica	hypothetical protein	0.0036	0.012	0.0169
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0202	0.0285
Loa Loa (eye worm)	nuclear receptor NHR-67	0.0048	0.0202	0.0285
Brugia malayi	hypothetical protein	0.0048	0.0202	0.0285
Brugia malayi	TAR-binding protein	0.0064	0.0318	0.0447
Brugia malayi	nuclear receptor RXR	0.0054	0.0243	0.0342
Brugia malayi	hypothetical protein	0.0054	0.0243	0.0342
Echinococcus granulosus	tar DNA binding protein	0.0064	0.0318	0.0318
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0102	0.0585	0.0585
Loa Loa (eye worm)	DR-78	0.0048	0.0202	0.0285
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0102	0.0585	0.0608
Mycobacterium ulcerans	DNA polymerase IV	0.002	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0102	0.0585	0.0823
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0102	0.0585	0.0823
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0102	0.0585	0.0608
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.137	0.9618	1
Entamoeba histolytica	tyrosyl-DNA phosphodiesterase, putative	0.1017	0.7105	1
Leishmania major	DNA polymerase eta, putative	0.0032	0.0088	0.0123
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0243	0.0342
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0102	0.0585	0.0585
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0048	0.0202	0.021
Brugia malayi	nuclear hormone receptor family member nhr-6	0.0048	0.0202	0.0285
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0102	0.0585	0.0823
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.0048	0.0202	0.021
Loa Loa (eye worm)	hypothetical protein	0.0102	0.0585	0.0823
Loa Loa (eye worm)	flap endonuclease-1	0.0026	0.0049	0.0068
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0048	0.0202	0.0202
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0191	0.0191
Brugia malayi	Steroid receptor seven-up type 2	0.0102	0.0585	0.0823
Brugia malayi	nuclear receptor NHR-88	0.0102	0.0585	0.0823
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0054	0.0243	0.0253
Loa Loa (eye worm)	hypothetical protein	0.0102	0.0585	0.0823
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0243	0.0342
Leishmania major	hypothetical protein, conserved	0.0026	0.0043	0.006
Trypanosoma brucei	PAB1-binding protein , putative	0.0026	0.0043	0.006
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0102	0.0585	0.0823
Echinococcus multilocularis	transcription factor Dp 1	0.0589	0.4054	0.4215
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0102	0.0585	0.0823
Echinococcus multilocularis	FTZ F1 alpha	0.0102	0.0585	0.0608
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0318	0.0318
Onchocerca volvulus		0.0102	0.0585	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0102	0.0585	0.0823
Mycobacterium ulcerans	DNA polymerase IV	0.002	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0202	0.0285
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0102	0.0585	0.0823
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0202	0.0285
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0064	0.0318	0.0447
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0102	0.0585	0.0823
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0202	0.0285
Mycobacterium tuberculosis	Conserved hypothetical protein	0.002	0	0.5
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0102	0.0585	0.0585
Echinococcus granulosus	flap endonuclease 1	0.0026	0.0049	0.0049
Loa Loa (eye worm)	TAR-binding protein	0.0064	0.0318	0.0447
Schistosoma mansoni	RAR-like nuclear receptor	0.0102	0.0585	0.0585
Brugia malayi	orphan nuclear receptor NR2E1	0.0048	0.0202	0.0285
Brugia malayi	hypothetical protein	0.0054	0.0243	0.0342
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0102	0.0585	0.0585
Brugia malayi	Nuclear hormone receptor-like 1	0.0054	0.0243	0.0342
Brugia malayi	ecdysone receptor	0.0048	0.0202	0.0285
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0102	0.0585	0.0823
Brugia malayi	nuclear hormone receptor	0.0048	0.0202	0.0285
Trichomonas vaginalis	flap endonuclease-1, putative	0.0026	0.0049	1
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0191	0.0191
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0036	0.012	0.012
Brugia malayi	nuclear hormone receptor	0.0102	0.0585	0.0823
Loa Loa (eye worm)	steroid hormone receptor	0.0102	0.0585	0.0823
Schistosoma mansoni	nuclear hormone receptor	0.0048	0.0202	0.0202
Entamoeba histolytica	hypothetical protein	0.0036	0.012	0.0169
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0048	0.0202	0.021
Schistosoma mansoni	nuclear receptor	0.0048	0.0202	0.0202
Brugia malayi	Tyrosyl-DNA phosphodiesterase family protein	0.1017	0.7105	1
Brugia malayi	Nuclear hormone receptor E75	0.0048	0.0202	0.0285

Activities

Activity type	Activity value	Assay description	Source	Reference
CC50 (ADMET)	= 20.09 uM	Cytotoxicity against human Hep2 cells	ChEMBL.	17616396
EC50 (functional)	= 1.807 uM	Antiviral activity against RSV Long in Hep2 cells	ChEMBL.	17616396

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL392049

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 444183