Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | cannabinoid receptor 2 (macrophage) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | serine/threonine protein kinase, putative | 0.0136 | 1 | 1 |
Brugia malayi | plexin A | 0.0087 | 0.5852 | 1 |
Trypanosoma brucei | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0136 | 1 | 1 |
Trypanosoma cruzi | Eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0136 | 1 | 1 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.0051 | 0.2847 | 0.3618 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0051 | 0.2847 | 1 |
Loa Loa (eye worm) | plexin A | 0.0087 | 0.5852 | 1 |
Brugia malayi | Plexin repeat family protein | 0.0073 | 0.4726 | 0.7608 |
Schistosoma mansoni | plexin | 0.0073 | 0.4726 | 1 |
Brugia malayi | intracellular kinase | 0.0051 | 0.2847 | 0.3618 |
Echinococcus granulosus | plexin a4 | 0.0087 | 0.5852 | 1 |
Plasmodium falciparum | glycogen synthase kinase 3 | 0.0051 | 0.2847 | 0.5 |
Trypanosoma cruzi | Eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0136 | 1 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase GSK, putative | 0.0051 | 0.2847 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0136 | 1 | 1 |
Echinococcus granulosus | glycogen synthase kinase 3 beta | 0.0051 | 0.2847 | 0.3618 |
Giardia lamblia | Kinase, CMGC GSK | 0.0051 | 0.2847 | 0.5 |
Giardia lamblia | Kinase, CMGC GSK | 0.0051 | 0.2847 | 0.5 |
Trichomonas vaginalis | STE family protein kinase | 0.0136 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0051 | 0.2847 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0051 | 0.2847 | 1 |
Echinococcus multilocularis | glycogen synthase kinase 3 beta | 0.0051 | 0.2847 | 0.3618 |
Echinococcus multilocularis | protein kinase shaggy | 0.0051 | 0.2847 | 0.3618 |
Echinococcus granulosus | protein kinase shaggy | 0.0051 | 0.2847 | 0.3618 |
Echinococcus multilocularis | plexin a4 | 0.0087 | 0.5852 | 1 |
Onchocerca volvulus | 0.0051 | 0.2847 | 0.4755 | |
Onchocerca volvulus | 0.0073 | 0.4726 | 1 | |
Schistosoma mansoni | plexin | 0.0043 | 0.2155 | 0.2822 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.0051 | 0.2847 | 0.3618 |
Trypanosoma cruzi | Eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0135 | 0.9909 | 0.9872 |
Schistosoma mansoni | glycogen synthase kinase 3-related (gsk3) (cmgc group III) | 0.0051 | 0.2847 | 0.4755 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2155 | 0.2147 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.2155 | 0.2822 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.4726 | 0.7608 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.