Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | hexose transporter | 0.0056 | 0.0121 | 1 |
Echinococcus multilocularis | geminin | 0.0175 | 0.0556 | 0.0534 |
Brugia malayi | Importin beta-1 subunit | 0.003 | 0.0024 | 0.0095 |
Echinococcus multilocularis | concentrative Na+ nucleoside cotransporter | 0.0346 | 0.1183 | 0.1162 |
Schistosoma mansoni | high-affinity choline transporter | 0.0702 | 0.2488 | 0.247 |
Echinococcus multilocularis | solute carrier family 5 | 0.2751 | 1 | 1 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.2751 | 1 | 1 |
Loa Loa (eye worm) | acetyltransferase | 0.015 | 0.0463 | 0.1861 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0056 | 0.0121 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0318 | 0.108 | 0.1059 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0044 | 0.0076 | 0.6162 |
Echinococcus granulosus | solute carrier family 28 | 0.0346 | 0.1183 | 0.1162 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.2751 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.0556 | 0.0534 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0056 | 0.0121 | 0.0098 |
Brugia malayi | Sodium:solute symporter family protein | 0.0702 | 0.2488 | 1 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0056 | 0.0121 | 0.0396 |
Plasmodium falciparum | hexose transporter | 0.0056 | 0.0121 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0702 | 0.2488 | 1 |
Schistosoma mansoni | glucose transport protein | 0.0056 | 0.0121 | 0.0098 |
Echinococcus multilocularis | snurportin 1 | 0.0318 | 0.108 | 0.1059 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0713 | 0.2527 | 0.2509 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0318 | 0.108 | 0.4339 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0044 | 0.0076 | 0.535 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0044 | 0.0076 | 0.0212 |
Leishmania major | importin beta-1 subunit, putative | 0.0024 | 0.0003 | 0.5 |
Brugia malayi | RNA, U transporter 1 | 0.0085 | 0.0225 | 0.0903 |
Schistosoma mansoni | hypothetical protein | 0.0056 | 0.0121 | 0.0098 |
Echinococcus granulosus | concentrative Na nucleoside cotransporter | 0.0346 | 0.1183 | 0.1162 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.2751 | 1 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0056 | 0.0121 | 0.0098 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0702 | 0.2488 | 0.247 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0056 | 0.0121 | 0.0098 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.015 | 0.0463 | 0.0441 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0713 | 0.2527 | 0.2509 |
Schistosoma mansoni | glucose transport protein | 0.0056 | 0.0121 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0024 | 0.0095 |
Schistosoma mansoni | inositol transporter | 0.2751 | 1 | 1 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0702 | 0.2488 | 0.247 |
Echinococcus granulosus | Na+ dependent nucleoside transporter | 0.0346 | 0.1183 | 0.1162 |
Loa Loa (eye worm) | hypothetical protein | 0.0702 | 0.2488 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0713 | 0.2527 | 0.2509 |
Brugia malayi | Sugar transporter family protein | 0.0056 | 0.0121 | 0.0487 |
Echinococcus multilocularis | General substrate transporter | 0.0051 | 0.0101 | 0.0077 |
Echinococcus granulosus | solute carrier family 5 | 0.2751 | 1 | 1 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.004 | 0.0062 | 0.3972 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.015 | 0.0463 | 0.1861 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0044 | 0.0076 | 0.6162 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0702 | 0.2488 | 0.247 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0056 | 0.0121 | 0.0098 |
Echinococcus multilocularis | solute carrier family 28 | 0.0346 | 0.1183 | 0.1162 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0056 | 0.0121 | 0.0098 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0702 | 0.2488 | 1 |
Onchocerca volvulus | 0.0702 | 0.2488 | 0.5 | |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0024 | 0.5 |
Echinococcus multilocularis | sodium:nucleoside cotransporter 2 | 0.0226 | 0.0742 | 0.072 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0056 | 0.0121 | 0.0098 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.004 | 0.0062 | 1 |
Schistosoma mansoni | sodium/solute symporter | 0.0702 | 0.2488 | 0.247 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0024 | 0.0003 | 0.5 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0044 | 0.0076 | 0.0212 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0056 | 0.0121 | 0.0098 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.2751 | 1 | 1 |
Echinococcus granulosus | General substrate transporter | 0.0051 | 0.0101 | 0.0077 |
Schistosoma mansoni | glucose transport protein | 0.0056 | 0.0121 | 0.0098 |
Schistosoma mansoni | inositol transporter | 0.2751 | 1 | 1 |
Loa Loa (eye worm) | sugar transporter | 0.0056 | 0.0121 | 0.0487 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0024 | 0.5 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.015 | 0.0463 | 0.0441 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0702 | 0.2488 | 0.247 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0044 | 0.0076 | 0.0052 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0056 | 0.0121 | 0.0098 |
Echinococcus granulosus | geminin | 0.0175 | 0.0556 | 0.0534 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.0556 | 0.0534 |
Echinococcus granulosus | snurportin 1 | 0.0318 | 0.108 | 0.1059 |
Brugia malayi | GH02984p | 0.0702 | 0.2488 | 1 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.004 | 0.0062 | 0.5 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0145 | 0.0448 | 0.0425 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.