Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | neuropeptide F receptor | 0.0042 | 0.0918 | 0.0918 |
Echinococcus granulosus | g protein coupled receptor | 0.0042 | 0.0918 | 0.1552 |
Onchocerca volvulus | 0.0026 | 0.0286 | 0.0484 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0042 | 0.0918 | 0.1552 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein | 0.002 | 0.0015 | 0.5 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0042 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0042 | 0.0918 | 0.1552 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0217 | 1 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | neuropeptide receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | neuropeptide receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | somatostatin receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | RE15519p | 0.0042 | 0.0918 | 0.0918 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Chlamydia trachomatis | arginine ABC transporter substrate-binding protein ArtJ | 0.002 | 0.0015 | 0.5 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | fmrfamide receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0108 | 0.3614 | 0.6113 |
Brugia malayi | neuropeptide F receptor | 0.0042 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | biogenic amine receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0286 | 0.0484 |
Echinococcus granulosus | g protein coupled receptor | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | sex peptide receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | putative neuropeptide receptor | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0027 | 0.0325 | 0.055 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0054 | 0.1401 | 0.237 |
Brugia malayi | AKH receptor | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | geminin | 0.0165 | 0.5912 | 1 |
Brugia malayi | Dopamine receptor protein 2 | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0054 | 0.1401 | 0.237 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0042 | 0.0918 | 0.1552 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0217 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | myosin xvIII | 0.0042 | 0.0918 | 0.1552 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Echinococcus granulosus | nmda type glutamate receptor | 0.0085 | 0.2669 | 0.4515 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.9418 | 1 |
Echinococcus granulosus | neuropeptide s receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0042 | 0.0918 | 0.1552 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.9418 | 1 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | serotonin receptor | 0.0042 | 0.0918 | 0.1552 |
Chlamydia trachomatis | glutamine binding protein | 0.002 | 0.0015 | 0.5 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | g protein coupled receptor | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | Serotonin receptor | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | amine GPCR | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Mycobacterium ulcerans | glutamine-binding lipoprotein GlnH | 0.002 | 0.0015 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0042 | 0.0918 | 0.1552 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0286 | 0.0484 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | adenoreceptor | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0286 | 0.0286 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0042 | 0.0918 | 0.1552 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0165 | 0.5912 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus granulosus | serotonin receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0081 | 0.2511 | 0.4247 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0217 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | opsin-like receptor | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | neuropeptide F receptor | 0.0042 | 0.0918 | 0.0918 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0174 | 0.6272 | 0.1027 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | lipoxygenase | 0.0054 | 0.1401 | 0.237 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | fmrfamide receptor | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Brugia malayi | Melatonin receptor type 1A | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | allatostatin A receptor | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0042 | 0.0918 | 0.1552 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.9418 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0042 | 0.0918 | 0.1552 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0217 | 0.5 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0286 | 0.0484 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0042 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Brugia malayi | G-protein coupled receptor | 0.0042 | 0.0918 | 0.0918 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0217 | 0.5 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | G-protein coupled receptor | 0.0042 | 0.0918 | 0.0918 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | amine GPCR | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0042 | 0.0918 | 0.1552 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein (hisJ) | 0.002 | 0.0015 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0042 | 0.0918 | 0.1552 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0286 | 0.0286 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | allatostatin A receptor | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | opsin-like receptor | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | larval opioid receptor | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0042 | 0.0918 | 0.0918 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0217 | 1 |
Echinococcus granulosus | sex peptide receptor | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0286 | 0.0286 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | Dopamine receptor protein 1 | 0.0042 | 0.0918 | 0.0918 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0042 | 0.0918 | 0.1552 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | Serotonin receptor | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | ORL1-like opioid receptor | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0042 | 0.0918 | 0.1552 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Brugia malayi | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | biogenic amine receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0286 | 0.0484 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.5912 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | neuropeptide receptor | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0266 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0252 | 0.9418 | 0.9418 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0286 | 0.0484 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | lamin | 0.0026 | 0.0286 | 0.0484 |
Echinococcus granulosus | g-protein coupled receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | histamine h1 receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | g protein coupled receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0093 | 0.2979 | 0.5039 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Mycobacterium tuberculosis | Probable glutamine-binding lipoprotein GlnH (GLNBP) | 0.002 | 0.0015 | 0.5 |
Brugia malayi | sulfakinin receptor protein | 0.0042 | 0.0918 | 0.0918 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0042 | 0.0918 | 0.0918 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | amine GPCR | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | geminin | 0.0165 | 0.5912 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0085 | 0.2669 | 0.4515 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0042 | 0.0918 | 0.1552 |
Onchocerca volvulus | 0.0026 | 0.0286 | 0.0484 | |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | Dopamine receptor | 0.0042 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | lamin | 0.0026 | 0.0286 | 0.0484 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0042 | 0.0918 | 0.1552 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0217 | 0.5 |
Echinococcus granulosus | orexin receptor type 2 | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.5912 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0042 | 0.0918 | 0.0918 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | GnHR receptor homolog | 0.0042 | 0.0918 | 0.0918 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0267 | 0.0267 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | neuropeptide receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Brugia malayi | G protein-coupled receptor | 0.0042 | 0.0918 | 0.0918 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0286 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.9418 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | neuropeptide receptor | 0.0042 | 0.0918 | 0.1552 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.9418 | 1 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | fmrfamide receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | lamin | 0.0026 | 0.0286 | 0.0484 |
Echinococcus multilocularis | g protein coupled receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | neuropeptide receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | glutamate receptor NMDA | 0.0081 | 0.2511 | 0.4247 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0174 | 0.6272 | 0.1027 |
Schistosoma mansoni | biogenic amine receptor | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | amine GPCR | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0042 | 0.0918 | 0.0918 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0217 | 0.0217 |
Echinococcus multilocularis | somatostatin receptor | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0252 | 0.9418 | 0.9418 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0286 | 0.0484 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0217 | 0.0217 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0918 | 0.1552 |
Echinococcus granulosus | neuropeptide receptor | 0.0042 | 0.0918 | 0.1552 |
Schistosoma mansoni | amine GPCR | 0.0042 | 0.0918 | 0.1552 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0217 | 0.5 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0042 | 0.0918 | 0.0918 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0108 | 0.3614 | 0.6113 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0042 | 0.0918 | 0.1552 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0042 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.9418 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0286 | 0.0286 |
Onchocerca volvulus | 0.0042 | 0.0918 | 0.1552 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | neuropeptide receptor | 0.0042 | 0.0918 | 0.1552 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0042 | 0.0918 | 0.0918 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0918 | 0.0918 |
Echinococcus multilocularis | serotonin receptor | 0.0042 | 0.0918 | 0.1552 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 19 % | Cell cycle arrest in human K562 cells assessed as accumulation at G2/M phase at 10 uM after 24 hrs by flow cytometry | ChEMBL. | 18293907 |
Activity (functional) | = 19 % | Cell cycle arrest in human K562 cells assessed as accumulation at G2/M phase at 10 uM after 24 hrs by flow cytometry | ChEMBL. | 18293907 |
Inhibition (binding) | = 2.7 % | Inhibition of ABCG2-mediated mitoxantrone efflux expressed in HEK293 cells at 2 uM after 48 hrs by flow cytometric analysis | ChEMBL. | 22449016 |
Inhibition (binding) | = 9.4 % | Inhibition of ABCG2-mediated mitoxantrone efflux expressed in HEK293 cells at 10 uM after 48 hrs by flow cytometric analysis | ChEMBL. | 22449016 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.