Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | membrane metallo-endopeptidase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.2776 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.2776 | 1 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0114 | 0.2776 | 1 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0114 | 0.2776 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0046 | 0.0528 | 0.1751 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0087 | 0.1878 | 1 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0114 | 0.2776 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0056 | 0.0857 | 0.3087 |
Brugia malayi | Peptidase family M13 containing protein | 0.0114 | 0.2776 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0087 | 0.1878 | 0.5 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0084 | 0.1796 | 0.6403 |
Schistosoma mansoni | kinase | 0.0044 | 0.0472 | 0.1701 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0087 | 0.1878 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1861 | 0.6642 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.2776 | 1 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0058 | 0.0915 | 0.3296 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1861 | 0.6642 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0087 | 0.1878 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0058 | 0.0915 | 0.3296 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0087 | 0.1878 | 0.1117 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0114 | 0.2776 | 0.2099 |
Schistosoma mansoni | neprilysin-2 (M13 family) | 0.0058 | 0.0915 | 0.3296 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1861 | 0.6642 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0333 | 1 | 1 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0087 | 0.1878 | 0.6704 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0051 | 0.0183 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0087 | 0.1878 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.1796 | 0.6403 |
Trypanosoma brucei | polo-like protein kinase | 0.0087 | 0.1878 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.1796 | 0.6403 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0087 | 0.1878 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0046 | 0.0528 | 0.1751 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1861 | 0.6642 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0087 | 0.1878 | 0.6704 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0114 | 0.2776 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.1796 | 0.6403 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.1796 | 0.6403 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0087 | 0.1878 | 1 |
Schistosoma mansoni | Nep2 peptidase (M13 family) | 0.0058 | 0.0915 | 0.3296 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0087 | 0.1878 | 0.5 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0084 | 0.1796 | 0.6403 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0087 | 0.1878 | 1 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0114 | 0.2776 | 0.2099 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0046 | 0.0528 | 0.1751 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0087 | 0.1878 | 1 |
Toxoplasma gondii | peptidase family M13 protein | 0.0114 | 0.2776 | 1 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0087 | 0.1878 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0087 | 0.1878 | 0.6765 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0056 | 0.0857 | 0.3087 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0087 | 0.1878 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0881 | 0.3045 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0087 | 0.1878 | 0.1117 |
Giardia lamblia | Kinase, PLK | 0.0087 | 0.1878 | 0.5 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0114 | 0.2776 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1861 | 0.6642 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0058 | 0.0915 | 0.3296 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1861 | 0.6642 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0528 | 0.1751 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.