TDR Targets

Basic information

Technical information

TDR Targets ID: 551325
Name: (2S)-2-amino-5-guanidino-N-(2-naphthyl)pentan amide
MW: 299.371 | Formula: C16H21N5O
H donors: 4 H acceptors: 1 LogP: 1.02 Rotable bonds: 8
Rule of 5 violations (Lipinski): 1
SMILES: NC(=N)NCCC[C@@H](C(=O)Nc1ccc2c(c1)cccc2)N
InChi: 1S/C16H21N5O/c17-14(6-3-9-20-16(18)19)15(22)21-13-8-7-11-4-1-2-5-12(11)10-13/h1-2,4-5,7-8,10,14H,3,6,9,17H2,(H,21,22)(H4,18,19,20)/t14-/m0/s1
InChiKey: DICSXQHGGOAUNU-AWEZNQCLSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

(2S)-2-amino-5-guanidino-N-(2-naphthalenyl)pentanamide
(2S)-2-azanyl-5-[bis(azanyl)methylideneamino]-N-naphthalen-2-yl-pentanamide
(2S)-2-amino-5-guanidino-N-(2-naphthyl)valeramide
(2S)-2-amino-5-(diaminomethylideneamino)-N-naphthalen-2-ylpentanamide
arginine beta-naphthylamide
(2S)-2-amino-5-(diaminomethylideneamino)-N-naphthalen-2-yl-pentanamide
Arg-beta-naphthylamide
Pentanamide, 2-amino-5-((aminoiminomethyl)amino)-N-2-naphthalenyl-, (S)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0312	0.1435
Loa Loa (eye worm)	hypothetical protein	0.0056	0.1084	0.4995
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0031	0.0496	0.2286
Trypanosoma brucei	glucose transporter, putative	0.0031	0.0506	0.8107
Plasmodium vivax	hexose transporter	0.0101	0.217	0.2094
Trichomonas vaginalis	glucose transporter, putative	0.0031	0.0506	0.2329
Plasmodium vivax	calcium-dependent protein kinase, putative	0.0031	0.0496	0.0404
Brugia malayi	Calcium/calmodulin-dependent protein kinase type II alpha chain	0.0031	0.0496	0.2286
Loa Loa (eye worm)	hypothetical protein	0.003	0.0481	0.2217
Onchocerca volvulus		0.0056	0.1084	1
Plasmodium falciparum	calcium-dependent protein kinase 2	0.0031	0.0496	0.0404
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0031	0.0496	0.2286
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0496	0.2286
Mycobacterium leprae	Probable prolyl tRNA synthetase ProS	0.003	0.0481	1
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Loa Loa (eye worm)	calcium/calmodulin-dependent protein kinase ID	0.0031	0.0496	0.2286
Schistosoma mansoni	hypothetical protein	0.0032	0.053	0.244
Echinococcus multilocularis	solute carrier family 2, facilitated glucose	0.0101	0.217	1
Brugia malayi	bifunctional aminoacyl-tRNA synthetase	0.003	0.0481	0.2217
Trypanosoma cruzi	lysyl-tRNA synthetase, putative	0.0023	0.0296	0.395
Trypanosoma brucei	glucose transporter, putative	0.0031	0.0506	0.8107
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0101	0.217	1
Toxoplasma gondii	facilitative glucose transporter GT1	0.0101	0.217	0.3201
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Brugia malayi	major facilitator superfamily protein	0.0014	0.0096	0.0444
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0345	0.1591
Loa Loa (eye worm)	hypothetical protein	0.003	0.0481	0.2217
Trichomonas vaginalis	conserved hypothetical protein	0.0014	0.0096	0.0444
Entamoeba histolytica	protein kinase, putative	0.0031	0.0496	1
Brugia malayi	Sugar transporter family protein	0.0014	0.0096	0.0444
Loa Loa (eye worm)	sema domain-containing protein	0.0023	0.0312	0.1435
Schistosoma mansoni	lysyl-tRNA synthetase	0.0023	0.0296	0.1363
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0101	0.217	1
Schistosoma mansoni	semaphorin 5-related	0.0023	0.0312	0.1435
Trichomonas vaginalis	myo-inositol transporter, putative	0.0014	0.0096	0.0444
Brugia malayi	Cam kinase protein 1	0.0031	0.0496	0.2286
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0031	0.0496	0.2286
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0101	0.217	1
Leishmania major	glucose transporter, lmgt3	0.0031	0.0506	0.8107
Schistosoma mansoni	protein kinase	0.0031	0.0496	0.2286
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.003	0.0481	0.2217
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Brugia malayi	Major Facilitator Superfamily protein	0.0014	0.0096	0.0444
Loa Loa (eye worm)	sema domain-containing protein	0.0023	0.0312	0.1435
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0296	0.1363
Trypanosoma cruzi	hexose transporter, putative	0.0031	0.0506	0.8107
Trichomonas vaginalis	conserved hypothetical protein	0.0014	0.0096	0.0444
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0035	0.0601	1
Entamoeba histolytica	tyrosin kinase, putative	0.0013	0.0065	0.1309
Schistosoma mansoni	glucose transport protein	0.0101	0.217	1
Plasmodium falciparum	hexose transporter	0.0101	0.217	0.2094
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0031	0.0506	0.8107
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0035	0.0601	1
Loa Loa (eye worm)	bifunctional aminoacyl-tRNA synthetase	0.0012	0.0054	0.025
Trypanosoma brucei	glucose transporter, putative	0.0031	0.0506	0.8107
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type 1	0.0031	0.0496	0.2286
Schistosoma mansoni	serine/threonine protein kinase	0.0031	0.0496	0.2286
Trichomonas vaginalis	conserved hypothetical protein	0.0101	0.217	1
Toxoplasma gondii	protein kinase, putative	0.0285	0.6576	1
Schistosoma mansoni	sugar transporter	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0101	0.217	1
Trichomonas vaginalis	prolyl-tRNA synthetase, putative	0.003	0.0481	0.2217
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0506	0.2329
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Brugia malayi	Plexin repeat family protein	0.0056	0.1084	0.4995
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0312	0.1435
Brugia malayi	Major Facilitator Superfamily protein	0.0014	0.0096	0.0444
Brugia malayi	Major Facilitator Superfamily protein	0.0014	0.0096	0.0444
Brugia malayi	hypothetical protein	0.0023	0.0312	0.1435
Chlamydia trachomatis	lysine--tRNA ligase	0.0023	0.0296	1
Trichomonas vaginalis	conserved hypothetical protein	0.0014	0.0096	0.0444
Mycobacterium ulcerans	sugar transporter	0.0014	0.0096	0.2954
Plasmodium vivax	calcium-dependent protein kinase 4, putative	0.0031	0.0496	0.0404
Loa Loa (eye worm)	sugar transporter	0.0101	0.217	1
Leishmania major	glucose transporter/membrane transporter D2, putative	0.0031	0.0506	0.8107
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0031	0.0496	0.2286
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.002	0.0229	0.1057
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Loa Loa (eye worm)	hypothetical protein	0.0032	0.053	0.244
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Leishmania major	lysyl-tRNA synthetase, putative	0.0023	0.0296	0.395
Trichomonas vaginalis	CAMK family protein kinase	0.0031	0.0496	0.2286
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Loa Loa (eye worm)	CAMK/CAMK2 protein kinase	0.0031	0.0496	0.2286
Echinococcus multilocularis	synaptic vesicle 2 protein	0.0014	0.0096	0.0444
Echinococcus granulosus	Sugar transporter ERD6 protein	0.0014	0.0096	0.0444
Toxoplasma gondii	lysine-tRNA ligase	0.0023	0.0296	0.0308
Echinococcus multilocularis	hypothetical protein	0.0023	0.0312	0.1435
Schistosoma mansoni	glucose transporter	0.0014	0.0096	0.0444
Trypanosoma cruzi	hexose transporter, putative	0.0031	0.0506	0.8107
Wolbachia endosymbiont of Brugia malayi	major facilitator superfamily permease	0.0014	0.0096	0.5
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0023	0.0296	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0312	0.1435
Echinococcus multilocularis	glutamyl tRNA synthetase cytoplasmic	0.003	0.0481	0.2217
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0506	0.2329
Trichomonas vaginalis	conserved hypothetical protein	0.0031	0.0506	0.2329
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Plasmodium falciparum	calcium-dependent protein kinase 1	0.0031	0.0496	0.0404
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Trypanosoma brucei	lysyl-tRNA synthetase, putative	0.0023	0.0296	0.395
Echinococcus multilocularis	lysyl tRNA synthetase	0.0023	0.0296	0.1363
Entamoeba histolytica	protein kinase domain containing protein	0.0013	0.0065	0.1309
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0014	0.0096	0.0444
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase)	0.0019	0.0215	1
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0031	0.0496	0.2286
Echinococcus granulosus	glutamyl tRNA synthetase cytoplasmic	0.003	0.0481	0.2217
Trypanosoma brucei	glucose transporter 2A	0.0031	0.0506	0.8107
Mycobacterium ulcerans	sugar-transport integral membrane protein SugI	0.0014	0.0096	0.2954
Schistosoma mansoni	glucose transport protein	0.0101	0.217	1
Schistosoma mansoni	plexin	0.0032	0.053	0.244
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Trypanosoma brucei	glucose transporter, putative	0.0031	0.0506	0.8107
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transport protein, putative	0.0014	0.0096	0.0444
Plasmodium vivax	calcium-dependent protein kinase 3, putative	0.0031	0.0496	0.0404
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Echinococcus multilocularis	solute carrier family 22	0.0014	0.0096	0.0444
Mycobacterium leprae	Possible lysyl-tRNA synthetase 2 LysX	0.0023	0.0296	0.3046
Trichomonas vaginalis	conserved hypothetical protein	0.0014	0.0096	0.0444
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.0023	0.0296	0.1363
Echinococcus multilocularis	semaphorin 5B	0.0023	0.0312	0.1435
Toxoplasma gondii	prolyl-tRNA synthetase (ProRS)	0.0035	0.0601	0.0779
Schistosoma mansoni	sugar transporter	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Echinococcus granulosus	solute carrier family 22	0.0014	0.0096	0.0444
Brugia malayi	hypothetical protein	0.0014	0.0096	0.0444
Plasmodium falciparum	proline--tRNA ligase	0.0035	0.0601	0.051
Echinococcus granulosus	calcium dependent protein kinase	0.0029	0.045	0.2075
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Brugia malayi	hypothetical protein	0.0014	0.0096	0.0444
Plasmodium falciparum	calcium-dependent protein kinase 5	0.0031	0.0496	0.0404
Trypanosoma brucei	glucose transporter 1E	0.0031	0.0506	0.8107
Brugia malayi	Bifunctional aminoacyl-tRNA synthetase	0.003	0.0481	0.2217
Schistosoma mansoni	plexin	0.0056	0.1084	0.4995
Toxoplasma gondii	calcium-dependent protein kinase CDPK3	0.0031	0.0496	0.0617
Entamoeba histolytica	hypothetical protein	0.0023	0.0296	0.5962
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Trypanosoma brucei	bifunctional aminoacyl-tRNA synthetase, putative	0.0035	0.0601	1
Brugia malayi	Sema domain containing protein	0.0023	0.0312	0.1435
Schistosoma mansoni	protein kinase	0.0031	0.0496	0.2286
Plasmodium vivax	proline--tRNA ligase, putative	0.0035	0.0601	0.051
Echinococcus multilocularis	calcium dependent protein kinase	0.0029	0.045	0.2075
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0312	0.1435
Trypanosoma cruzi	hexose transporter	0.0031	0.0506	0.8107
Echinococcus granulosus	synaptic vesicle 2 protein	0.0014	0.0096	0.0444
Plasmodium falciparum	lysine--tRNA ligase	0.0023	0.0296	0.0201
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0101	0.217	1
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0031	0.0506	0.8107
Trichomonas vaginalis	glucose transporter, putative	0.0031	0.0506	0.2329
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0035	0.0601	1
Plasmodium vivax	mitogen-activated protein kinase 2, putative	0.0163	0.3657	0.3595
Brugia malayi	Sugar transporter family protein	0.0014	0.0096	0.0444
Leishmania major	glucose transporter, lmgt1	0.0031	0.0506	0.8107
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0023	0.0296	1
Trypanosoma cruzi	hexose transporter, putative	0.0031	0.0506	0.8107
Mycobacterium ulcerans	fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT	0.0014	0.0096	0.2954
Trypanosoma brucei	calcium/calmodulin-dependent protein kinase, putative	0.0031	0.0496	0.7919
Plasmodium falciparum	protein kinase 7	0.0285	0.6576	0.6542
Echinococcus multilocularis	Sugar transporter ERD6 protein	0.0014	0.0096	0.0444
Echinococcus granulosus	lysyl tRNA synthetase	0.0023	0.0296	0.1363
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0035	0.0601	1
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Schistosoma mansoni	glucose transport protein	0.0101	0.217	1
Echinococcus multilocularis	General substrate transporter	0.0087	0.1831	0.8437
Schistosoma mansoni	lysyl-tRNA synthetase	0.0023	0.0296	0.1363
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 2 LysX	0.0019	0.0215	1
Loa Loa (eye worm)	sugar transporter	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0506	0.2329
Leishmania major	glucose transporter, lmgt2	0.0031	0.0506	0.8107
Toxoplasma gondii	cell-cycle-associated protein kinase MAPK, putative	0.0163	0.3657	0.5495
Echinococcus multilocularis	plexin a4	0.0066	0.1327	0.6114
Schistosoma mansoni	sugar transporter	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0101	0.217	1
Echinococcus granulosus	semaphorin 1A	0.0023	0.0312	0.1435
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Brugia malayi	Sema domain containing protein	0.0023	0.0312	0.1435
Giardia lamblia	Lysyl-tRNA synthetase	0.0023	0.0296	0.5182
Plasmodium vivax	lysine--tRNA ligase, putative	0.0023	0.0296	0.0201
Trypanosoma brucei	glucose transporter, putative	0.0031	0.0506	0.8107
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0312	0.1435
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Schistosoma mansoni	nuclear transcription factor X-box binding 1 (nfx1)	0.0014	0.0096	0.0444
Entamoeba histolytica	prolyl-tRNA synthetase, putative	0.003	0.0481	0.9698
Toxoplasma gondii	calcium-dependent protein kinase CDPK2B	0.0031	0.0496	0.0617
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.003	0.0481	0.2217
Brugia malayi	major facilitator superfamily protein	0.0014	0.0096	0.0444
Brugia malayi	lysyl-tRNA synthetase	0.0023	0.0296	0.1363
Trypanosoma brucei	glucose transporter, putative	0.0031	0.0506	0.8107
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Trypanosoma brucei	glucose transporter, putative	0.0031	0.0506	0.8107
Echinococcus multilocularis	solute carrier family 22	0.0014	0.0096	0.0444
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0031	0.0496	0.2286
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Echinococcus granulosus	semaphorin 5B	0.0023	0.0312	0.1435
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0312	0.1435
Echinococcus granulosus	plexin a4	0.0066	0.1327	0.6114
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Plasmodium falciparum	calcium-dependent protein kinase 3	0.0031	0.0496	0.0404
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Mycobacterium ulcerans	integral membrane transport protein	0.0014	0.0096	0.2954
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0031	0.0496	0.2286
Echinococcus multilocularis	solute carrier family 22	0.0014	0.0096	0.0444
Echinococcus granulosus	solute carrier family 22	0.0014	0.0096	0.0444
Loa Loa (eye worm)	plexin A	0.0066	0.1327	0.6114
Trypanosoma brucei	glucose transporter, putative	0.0031	0.0506	0.8107
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0031	0.0506	0.8107
Giardia lamblia	Prolyl-tRNA synthetase	0.003	0.0481	1
Echinococcus multilocularis	solute carrier family 22	0.0014	0.0096	0.0444
Trichomonas vaginalis	conserved hypothetical protein	0.0031	0.0506	0.2329
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0101	0.217	1
Brugia malayi	hypothetical protein	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Plasmodium falciparum	calcium-dependent protein kinase 4	0.0031	0.0496	0.0404
Trypanosoma cruzi	hexose transporter, putative	0.0017	0.0166	0.1383
Entamoeba histolytica	protein kinase, putative	0.0031	0.0496	1
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Leishmania major	protein kinase, putative	0.0031	0.0496	0.7919
Toxoplasma gondii	calcium-dependent protein kinase CDPK2A	0.0031	0.0496	0.0617
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Plasmodium falciparum	mitogen-activated protein kinase 2	0.0163	0.3657	0.3595
Schistosoma mansoni	hypothetical protein	0.0023	0.0312	0.1435
Echinococcus granulosus	solute carrier family 22	0.0014	0.0096	0.0444
Trichomonas vaginalis	glucose transporter, putative	0.0014	0.0096	0.0444
Trichomonas vaginalis	conserved hypothetical protein	0.0014	0.0096	0.0444
Brugia malayi	hypothetical protein	0.0023	0.0312	0.1435
Schistosoma mansoni	hypothetical protein	0.0023	0.0312	0.1435
Plasmodium vivax	calcium-dependent protein kinase 1, putative	0.0031	0.0496	0.0404
Onchocerca volvulus		0.0023	0.0312	0.2178
Schistosoma mansoni	hypothetical protein	0.0101	0.217	1
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Treponema pallidum	prolyl-tRNA synthetase	0.0011	0.0013	0.5
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Echinococcus granulosus	General substrate transporter	0.0087	0.1831	0.8437
Schistosoma mansoni	protein kinase	0.0031	0.0496	0.2286
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Brugia malayi	Sugar transporter family protein	0.0101	0.217	1
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0014	0.0096	0.0444
Trichomonas vaginalis	sugar transporter, putative	0.0014	0.0096	0.0444
Plasmodium vivax	CDK-related protein kinase 6, putative	0.0429	1	1
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0096	0.0444
Echinococcus granulosus	solute carrier family 22	0.0014	0.0096	0.0444
Brugia malayi	plexin A	0.0066	0.1327	0.6114
Schistosoma mansoni	sugar transporter	0.0014	0.0096	0.0444

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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PubChem: 151452

Bibliographic References

No literature references available for this target.

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Detailed information for compound 551325