Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.2837 | 0.2837 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.2114 | 0.2114 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0134 | 0.2837 | 0.2837 |
Trypanosoma cruzi | endonuclease G, putative | 0.008 | 0.1001 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.4226 | 0.3584 |
Trypanosoma brucei | endonuclease G, putative | 0.008 | 0.1001 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Onchocerca volvulus | 0.0134 | 0.2837 | 0.0481 | |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Toxoplasma gondii | DNA/RNA non-specific endonuclease | 0.008 | 0.1001 | 0.5 |
Onchocerca volvulus | 0.0134 | 0.2837 | 0.0481 | |
Schistosoma mansoni | hypothetical protein | 0.0288 | 0.8166 | 0.7962 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Trypanosoma brucei | endonuclease G, putative | 0.008 | 0.1001 | 0.5 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Echinococcus multilocularis | geminin | 0.0174 | 0.4226 | 0.3584 |
Brugia malayi | hypothetical protein | 0.0126 | 0.2568 | 0.2568 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.008 | 0.1001 | 0.5 |
Brugia malayi | Thrombospondin type 1 domain containing protein | 0.0288 | 0.8166 | 0.8166 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0341 | 1 | 1 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0341 | 1 | 1 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.0288 | 0.8166 | 0.8166 |
Trypanosoma brucei | endonuclease G, putative | 0.008 | 0.1001 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.4226 | 0.3584 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0113 | 0.2114 | 0.1237 |
Onchocerca volvulus | 0.0288 | 0.8166 | 1 | |
Leishmania major | endonuclease G, putative | 0.008 | 0.1001 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.2568 | 0.2568 |
Echinococcus granulosus | geminin | 0.0174 | 0.4226 | 0.3584 |
Trypanosoma cruzi | endonuclease G, putative | 0.008 | 0.1001 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.2837 | 0.2837 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.008 | 0.1001 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0113 | 0.2114 | 0.1237 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0341 | 1 | 1 |
Echinococcus multilocularis | ectonucleotide | 0.0113 | 0.2114 | 0.1237 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0341 | 1 | 1 |
Echinococcus granulosus | ectonucleotide | 0.0113 | 0.2114 | 0.1237 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.2568 | 0.2568 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.2837 | 0.2837 |
Leishmania major | DNA/RNA non-specific endonuclease-like protein | 0.008 | 0.1001 | 0.5 |
Brugia malayi | endonuclease G, mitochondrial precursor | 0.008 | 0.1001 | 0.1001 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0134 | 0.2837 | 0.204 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.