Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.2136 | 0.2136 |
Schistosoma mansoni | plexin | 0.0056 | 0.6883 | 0.6883 |
Echinococcus multilocularis | roundabout 2 | 0.0033 | 0.2136 | 0.2361 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0033 | 0.1981 | 0.1981 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.2136 | 0.2136 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0033 | 0.2136 | 0.2136 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0033 | 0.2136 | 0.2136 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.2136 | 0.2136 |
Echinococcus multilocularis | Immunoglobulin | 0.0033 | 0.2136 | 0.2361 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.1981 | 0.219 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1981 | 0.1981 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.1981 | 0.219 |
Brugia malayi | plexin A | 0.0066 | 0.9047 | 0.9047 |
Onchocerca volvulus | 0.0033 | 0.1981 | 0.1981 | |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.2136 | 0.2136 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.1981 | 0.219 |
Brugia malayi | Plexin repeat family protein | 0.0056 | 0.6883 | 0.6883 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.2136 | 0.2136 |
Brugia malayi | hypothetical protein | 0.0033 | 0.2136 | 0.2136 |
Onchocerca volvulus | 0.007 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.6883 | 0.6883 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.1981 | 0.219 |
Echinococcus granulosus | defective proboscis extension response | 0.0033 | 0.2136 | 0.2361 |
Echinococcus multilocularis | plexin a4 | 0.0066 | 0.9047 | 1 |
Echinococcus multilocularis | neuroglian | 0.0033 | 0.2136 | 0.2361 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.1981 | 0.219 |
Schistosoma mansoni | hypothetical protein | 0.007 | 1 | 1 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0033 | 0.1981 | 0.1981 |
Echinococcus multilocularis | ectonucleotide | 0.0027 | 0.0892 | 0.0986 |
Echinococcus granulosus | neuroglian | 0.0033 | 0.2136 | 0.2361 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0033 | 0.2136 | 0.2361 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.2136 | 0.2136 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.1943 | 0.1943 |
Echinococcus granulosus | plexin a4 | 0.0066 | 0.9047 | 1 |
Schistosoma mansoni | vesicular amine transporter | 0.0033 | 0.2136 | 0.2136 |
Onchocerca volvulus | 0.0033 | 0.1981 | 0.1981 | |
Echinococcus granulosus | Immunoglobulin | 0.0033 | 0.2136 | 0.2361 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0033 | 0.1981 | 0.1981 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.1981 | 0.219 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.1981 | 0.219 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0033 | 0.2136 | 0.2361 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0039 | 0.3357 | 0.3357 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.1981 | 0.219 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.2136 | 0.2136 |
Echinococcus multilocularis | Immunoglobulin | 0.0033 | 0.2136 | 0.2361 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0892 | 0.0892 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.1943 | 0.1943 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.1981 | 0.219 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0033 | 0.1981 | 0.1981 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.1981 | 0.219 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0039 | 0.3357 | 0.3357 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0027 | 0.0892 | 0.0986 |
Loa Loa (eye worm) | plexin A | 0.0066 | 0.9047 | 0.9047 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0033 | 0.2136 | 0.2136 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0027 | 0.0892 | 0.0986 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0033 | 0.1981 | 0.1981 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1981 | 0.1981 |
Schistosoma mansoni | cell adhesion molecule | 0.0033 | 0.2136 | 0.2136 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1981 | 0.1981 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.1981 | 0.219 |
Echinococcus granulosus | twitchin | 0.0033 | 0.2136 | 0.2361 |
Echinococcus granulosus | roundabout 2 | 0.0033 | 0.2136 | 0.2361 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.007 | 1 | 1 |
Echinococcus granulosus | ectonucleotide | 0.0027 | 0.0892 | 0.0986 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0033 | 0.2136 | 0.2136 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.2136 | 0.2136 |
Onchocerca volvulus | 0.0056 | 0.6883 | 0.6883 | |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.2136 | 0.2136 |
Schistosoma mansoni | nephrin | 0.0033 | 0.2136 | 0.2136 |
Schistosoma mansoni | plexin | 0.0032 | 0.1943 | 0.1943 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.