Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.1011 | 0.1221 |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.1011 | 0.1221 |
Schistosoma mansoni | ferritin light chain | 0.0008 | 0.0056 | 0.0056 |
Onchocerca volvulus | 0.0023 | 0.1011 | 1 | |
Brugia malayi | Carboxylesterase family protein | 0.0139 | 0.8286 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.8286 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0023 | 0.1011 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0009 | 0.0102 | 0.0477 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0023 | 0.1011 | 0.1011 |
Echinococcus multilocularis | expressed protein | 0.0008 | 0.0056 | 0.0056 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0023 | 0.1011 | 0.1011 |
Brugia malayi | Carboxylesterase family protein | 0.0139 | 0.8286 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1011 | 0.1221 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0023 | 0.1011 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.1011 | 0.1221 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.1011 | 0.1221 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.1011 | 0.1011 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0008 | 0.0056 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1011 | 0.1221 |
Onchocerca volvulus | 0.0023 | 0.1011 | 1 | |
Brugia malayi | Cytochrome P450 family protein | 0.0009 | 0.0102 | 0.0123 |
Echinococcus granulosus | acetylcholinesterase | 0.0139 | 0.8286 | 0.8286 |
Echinococcus granulosus | expressed protein | 0.0008 | 0.0056 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1011 | 0.1221 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0008 | 0.0056 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0009 | 0.0102 | 0.0123 |
Schistosoma mansoni | apoferritin-2 | 0.0008 | 0.0056 | 0.0056 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0023 | 0.1011 | 0.1011 |
Brugia malayi | Cytochrome P450 family protein | 0.0009 | 0.0102 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1011 | 0.1221 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0139 | 0.8286 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0023 | 0.1011 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0139 | 0.8286 | 0.8286 |
Brugia malayi | hypothetical protein | 0.0023 | 0.1011 | 0.1221 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.1011 | 0.1221 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.8286 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.1011 | 0.1011 |
Schistosoma mansoni | ferritin | 0.0008 | 0.0056 | 0.0056 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0023 | 0.1011 | 0.1011 |
Echinococcus multilocularis | geminin | 0.0166 | 1 | 1 |
Onchocerca volvulus | 0.0023 | 0.1011 | 1 | |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.1011 | 0.1221 |
Echinococcus granulosus | acetylcholinesterase | 0.0139 | 0.8286 | 0.8286 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0023 | 0.1011 | 0.1011 |
Trypanosoma brucei | cytochrome P450, putative | 0.0009 | 0.0102 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0139 | 0.8286 | 1 |
Schistosoma mansoni | ferritin light chain | 0.0008 | 0.0056 | 0.0056 |
Echinococcus granulosus | neuroligin | 0.0023 | 0.1011 | 0.1011 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0008 | 0.0056 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0139 | 0.8286 | 0.8286 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0009 | 0.0102 | 0.0123 |
Onchocerca volvulus | 0.0023 | 0.1011 | 1 | |
Trypanosoma cruzi | cytochrome P450, putative | 0.0009 | 0.0102 | 0.5 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0023 | 0.1011 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0023 | 0.1011 | 1 |
Schistosoma mansoni | apoferritin-2 | 0.0008 | 0.0056 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1011 | 0.1221 |
Schistosoma mansoni | ferritin | 0.0008 | 0.0056 | 0.0056 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0023 | 0.1011 | 1 |
Echinococcus multilocularis | ferritin | 0.0008 | 0.0056 | 0.0056 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0139 | 0.8286 | 0.8286 |
Leishmania major | cytochrome p450-like protein | 0.0009 | 0.0102 | 0.5 |
Schistosoma mansoni | ferritin | 0.0008 | 0.0056 | 0.0056 |
Schistosoma mansoni | acetylcholinesterase | 0.0023 | 0.1011 | 0.1011 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0009 | 0.0102 | 0.0123 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0139 | 0.8286 | 0.8286 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.1011 | 0.1011 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1011 | 0.1221 |
Echinococcus multilocularis | neuroligin | 0.0023 | 0.1011 | 0.1011 |
Schistosoma mansoni | ferritin | 0.0008 | 0.0056 | 0.0056 |
Onchocerca volvulus | 0.0023 | 0.1011 | 1 | |
Trypanosoma cruzi | cytochrome P450, putative | 0.0009 | 0.0102 | 0.5 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0023 | 0.1011 | 0.1011 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1011 | 0.1221 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0023 | 0.1011 | 0.1011 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0023 | 0.1011 | 0.1011 |
Echinococcus multilocularis | acetylcholinesterase | 0.0139 | 0.8286 | 0.8286 |
Echinococcus granulosus | ferritin | 0.0008 | 0.0056 | 0.0056 |
Schistosoma mansoni | gliotactin | 0.0023 | 0.1011 | 0.1011 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.