Detailed information for compound 626943

Basic information

Technical information
  • TDR Targets ID: 626943
  • Name: N-(4-ethyl-1,3-benzothiazol-2-yl)-4-(2-methyl piperidin-1-yl)sulfonylbenzamide
  • MW: 443.582 | Formula: C22H25N3O3S2
  • H donors: 1 H acceptors: 4 LogP: 4.77 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1cccc2c1nc(s2)NC(=O)c1ccc(cc1)S(=O)(=O)N1CCCCC1C
  • InChi: 1S/C22H25N3O3S2/c1-3-16-8-6-9-19-20(16)23-22(29-19)24-21(26)17-10-12-18(13-11-17)30(27,28)25-14-5-4-7-15(25)2/h6,8-13,15H,3-5,7,14H2,1-2H3,(H,23,24,26)
  • InChiKey: PSZQRLAZHWQSKC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(4-ethyl-1,3-benzothiazol-2-yl)-4-[(2-methyl-1-piperidyl)sulfonyl]benzamide
  • N-(4-ethyl-1,3-benzothiazol-2-yl)-4-[(2-methyl-1-piperidinyl)sulfonyl]benzamide
  • N-(4-ethyl-1,3-benzothiazol-2-yl)-4-(2-methylpiperidin-1-yl)sulfonyl-benzamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum lysine--tRNA ligase 0.0047 0.0283 0.0208
Plasmodium falciparum proline--tRNA ligase 0.0073 0.0589 0.0516
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0084 0.003
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Leishmania major glucose transporter/membrane transporter D2, putative 0.0065 0.0493 0.4592
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0493 0.1776
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.0976 1
Giardia lamblia Hexose transporter 0.003 0.0084 0.0177
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0152 0.0338
Schistosoma mansoni glucose transport protein 0.021 0.216 1
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.003 0.0084 0.0007
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0084 0.0011
Onchocerca volvulus 0.003 0.0084 0.001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0081 0.0188
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0047 0.0283 0.0881
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0283 0.2903
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Plasmodium falciparum mitogen-activated protein kinase 2 0.0339 0.3649 0.36
Onchocerca volvulus 0.003 0.0084 0.001
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0063 0.0469 0.4361
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.216 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Giardia lamblia Sugar-proton symporter 0.003 0.0084 0.0177
Echinococcus granulosus Sugar transporter ERD6 protein 0.003 0.0084 0.007
Brugia malayi hypothetical protein 0.003 0.0084 0.0011
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Trypanosoma brucei glucose transporter, putative 0.0065 0.0493 0.4592
Plasmodium falciparum calcium-dependent protein kinase 1 0.0064 0.0484 0.0411
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.003 0.0084 0.0011
Echinococcus multilocularis synaptic vesicle 2 protein 0.003 0.0084 0.0011
Echinococcus multilocularis solute carrier family 22 0.003 0.0084 0.0011
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.216 1
Toxoplasma gondii sugar transporter ST2 0.003 0.0084 0.0011
Echinococcus granulosus General substrate transporter 0.018 0.1821 0.8375
Onchocerca volvulus 0.003 0.0084 0.001
Toxoplasma gondii lysine-tRNA ligase 0.0047 0.0283 0.0318
Plasmodium vivax CDK-related protein kinase 6, putative 0.0891 1 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Plasmodium vivax hexose transporter 0.021 0.216 0.21
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0976 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0493 0.1776
Leishmania major protein kinase, putative 0.0064 0.0484 0.4485
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0064 0.0484 0.0628
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0976 1
Onchocerca volvulus 0.003 0.0084 0.001
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0047 0.0283 0.2237
Mycobacterium ulcerans sugar transporter 0.003 0.0084 0.0858
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0976 0.441
Echinococcus granulosus lysyl tRNA synthetase 0.0047 0.0283 0.1025
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Loa Loa (eye worm) phosphofructokinase 0.0107 0.0976 0.441
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.0976 1
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0063 0.0469 0.3449
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0084 0.0199
Schistosoma mansoni glucose transporter 0.003 0.0084 0.0011
Plasmodium falciparum calcium-dependent protein kinase 4 0.0064 0.0484 0.0411
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0084 0.0011
Brugia malayi Sugar transporter family protein 0.003 0.0084 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0484 0.1936
Brugia malayi lysyl-tRNA synthetase 0.0047 0.0283 0.0971
Trypanosoma brucei glucose transporter, putative 0.0065 0.0493 0.4592
Entamoeba histolytica hypothetical protein 0.0035 0.0152 0.0833
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0084 0.003
Onchocerca volvulus 0.003 0.0084 0.001
Onchocerca volvulus 0.003 0.0084 0.001
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.2097 0.97
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0084 0.0199
Trypanosoma brucei glucose transporter, putative 0.0065 0.0493 0.4592
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Brugia malayi Pre-SET motif family protein 0.0204 0.2097 0.9694
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0064 0.0484 0.0411
Leishmania major glucose transporter, lmgt2 0.0065 0.0493 0.4592
Onchocerca volvulus 0.003 0.0084 0.001
Entamoeba histolytica protein kinase, putative 0.0064 0.0484 0.4528
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0493 0.1776
Trypanosoma brucei glucose transporter 2A 0.0065 0.0493 0.4592
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.004 0.0202 0.1326
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Plasmodium vivax proline--tRNA ligase, putative 0.0073 0.0589 0.0516
Entamoeba histolytica hypothetical protein 0.0047 0.0283 0.2297
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Loa Loa (eye worm) hypothetical protein 0.0063 0.0469 0.2017
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.003 0.0084 0.0858
Brugia malayi RNA recognition motif domain containing protein 0.0125 0.1178 0.5275
Plasmodium falciparum protein kinase 7 0.0593 0.6571 0.6545
Trypanosoma brucei glucose transporter 1E 0.0065 0.0493 0.4592
Entamoeba histolytica hypothetical protein 0.0035 0.0152 0.0833
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Echinococcus multilocularis General substrate transporter 0.018 0.1821 0.8366
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0339 0.3649 0.36
Trichomonas vaginalis sugar transport protein, putative 0.003 0.0084 0.003
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0589 0.5664
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0493 0.4592
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.021 0.216 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0152 0.0395
Giardia lamblia Lysyl-tRNA synthetase 0.0047 0.0283 0.5267
Echinococcus granulosus calcium dependent protein kinase 0.006 0.0438 0.1765
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.216 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Toxoplasma gondii sugar transporter ST3 0.003 0.0084 0.0011
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0484 0.1936
Schistosoma mansoni protein kinase 0.0064 0.0484 0.1936
Echinococcus multilocularis calcium dependent protein kinase 0.006 0.0438 0.1716
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Onchocerca volvulus 0.003 0.0084 0.001
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0063 0.0469 0.1864
Schistosoma mansoni glucose transport protein 0.021 0.216 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0283 0.2903
Brugia malayi Sugar transporter family protein 0.003 0.0084 0.0011
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0047 0.0283 0.2237
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Schistosoma mansoni hypothetical protein 0.0166 0.166 0.7591
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0493 0.1776
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0064 0.0484 0.0628
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0064 0.0484 0.4485
Schistosoma mansoni sugar transporter 0.003 0.0084 0.0011
Loa Loa (eye worm) hypothetical protein 0.0064 0.0484 0.2088
Schistosoma mansoni tar DNA-binding protein 0.0125 0.1178 0.5275
Schistosoma mansoni tar DNA-binding protein 0.0125 0.1178 0.5275
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0976 0.3834
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0469 0.1864
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.021 0.216 1
Onchocerca volvulus 0.003 0.0084 0.001
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0589 0.5664
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Echinococcus granulosus solute carrier family 22 0.003 0.0084 0.007
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0589 0.5664
Plasmodium vivax lysine--tRNA ligase, putative 0.0047 0.0283 0.0208
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0064 0.0484 0.2088
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0125 0.1178 0.5364
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0976 1
Trypanosoma brucei glucose transporter, putative 0.0065 0.0493 0.4592
Brugia malayi hypothetical protein 0.003 0.0084 0.0011
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0339 0.3649 0.55
Entamoeba histolytica hypothetical protein 0.0035 0.0152 0.0833
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.0976 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Plasmodium falciparum calcium-dependent protein kinase 2 0.0064 0.0484 0.0411
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.0976 1
Loa Loa (eye worm) TAR-binding protein 0.0125 0.1178 0.5364
Schistosoma mansoni glucose transport protein 0.021 0.216 1
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0283 0.0971
Leishmania major lysyl-tRNA synthetase, putative 0.0047 0.0283 0.2237
Echinococcus granulosus solute carrier family 22 0.003 0.0084 0.007
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0064 0.0484 0.0411
Loa Loa (eye worm) hypothetical protein 0.0063 0.0469 0.2017
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0493 0.1776
Onchocerca volvulus 0.003 0.0084 0.001
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0976 0.4302
Echinococcus granulosus synaptic vesicle 2 protein 0.003 0.0084 0.007
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Trichomonas vaginalis glucose transporter, putative 0.003 0.0084 0.003
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0064 0.0484 0.2088
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0202 0.1326
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Plasmodium vivax sugar transporter, putative 0.003 0.0084 0.0007
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.0217 0.0597
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0976 1
Brugia malayi major facilitator superfamily protein 0.003 0.0084 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0084 0.003
Brugia malayi RNA binding protein 0.0125 0.1178 0.5275
Onchocerca volvulus 0.003 0.0084 0.001
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0484 0.1936
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Plasmodium vivax SET domain protein, putative 0.0029 0.0081 0.0005
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0064 0.0484 0.0628
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.0976 0.4302
Mycobacterium ulcerans integral membrane transport protein 0.003 0.0084 0.0858
Brugia malayi phosphofructokinase 0.0107 0.0976 0.4302
Plasmodium falciparum calcium-dependent protein kinase 5 0.0064 0.0484 0.0411
Echinococcus multilocularis solute carrier family 22 0.003 0.0084 0.0011
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Schistosoma mansoni tar DNA-binding protein 0.0125 0.1178 0.5275
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0484 0.1936
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.003 0.0084 0.0858
Toxoplasma gondii transporter, major facilitator family protein 0.003 0.0084 0.0011
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Brugia malayi major facilitator superfamily protein 0.003 0.0084 0.0011
Chlamydia trachomatis lysine--tRNA ligase 0.0047 0.0283 1
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0493 0.1776
Trypanosoma brucei glucose transporter, putative 0.0065 0.0493 0.4592
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.216 1
Entamoeba histolytica hypothetical protein 0.0035 0.0152 0.0833
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0063 0.0469 0.1672
Onchocerca volvulus 0.003 0.0084 0.001
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0063 0.0469 0.1912
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Trypanosoma cruzi hexose transporter 0.0065 0.0493 0.4592
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0493 0.4592
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Onchocerca volvulus 0.003 0.0084 0.001
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0047 0.0283 0.1051
Schistosoma mansoni tar DNA-binding protein 0.0125 0.1178 0.5275
Echinococcus granulosus solute carrier family 22 0.003 0.0084 0.007
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.0976 1
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0063 0.0469 0.1864
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Leishmania major glucose transporter, lmgt3 0.0065 0.0493 0.4592
Onchocerca volvulus 0.003 0.0084 0.001
Schistosoma mansoni protein kinase 0.0064 0.0484 0.1936
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0081 0.0007
Schistosoma mansoni sugar transporter 0.003 0.0084 0.0011
Plasmodium vivax calcium-dependent protein kinase, putative 0.0064 0.0484 0.0411
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0484 0.1984
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0493 0.4592
Trypanosoma brucei glucose transporter, putative 0.0065 0.0493 0.4592
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0154 0.0783
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0064 0.0484 0.1984
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0064 0.0484 0.0411
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Echinococcus multilocularis lysyl tRNA synthetase 0.0047 0.0283 0.0971
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0976 0.3834
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0493 0.4592
Schistosoma mansoni protein kinase 0.0064 0.0484 0.1936
Brugia malayi 6-phosphofructokinase 0.0107 0.0976 0.4302
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0084 0.0011
Echinococcus multilocularis solute carrier family 22 0.003 0.0084 0.0011
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.021 0.216 1
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0469 0.1864
Loa Loa (eye worm) hypothetical protein 0.0051 0.0333 0.1375
Brugia malayi hypothetical protein 0.003 0.0084 0.0011
Echinococcus multilocularis solute carrier family 22 0.003 0.0084 0.0011
Entamoeba histolytica protein kinase, putative 0.0064 0.0484 0.4528
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0589 0.5664
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0063 0.0469 0.1864
Onchocerca volvulus Putative transporter 0.003 0.0084 0.001
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.0976 0.4336
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0589 0.5664
Trichomonas vaginalis conserved hypothetical protein 0.021 0.216 0.8885
Onchocerca volvulus 0.0233 0.2422 1
Toxoplasma gondii protein kinase, putative 0.0593 0.6571 1
Echinococcus granulosus tar DNA binding protein 0.0125 0.1178 0.5303
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0976 0.3834
Echinococcus multilocularis tar DNA binding protein 0.0125 0.1178 0.5275
Toxoplasma gondii sugar transporter ST1 0.003 0.0084 0.0011
Schistosoma mansoni sugar transporter 0.003 0.0084 0.0011
Brugia malayi TAR-binding protein 0.0125 0.1178 0.5275
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0081 0.0059
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0976 1
Plasmodium falciparum hexose transporter 0.021 0.216 0.21
Schistosoma mansoni hypothetical protein 0.021 0.216 1
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0077 0.2709
Schistosoma mansoni tar DNA-binding protein 0.0125 0.1178 0.5275
Trichomonas vaginalis myo-inositol transporter, putative 0.003 0.0084 0.003
Loa Loa (eye worm) sugar transporter 0.003 0.0084 0.0199
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0064 0.0484 0.1936
Schistosoma mansoni hypothetical protein 0.0166 0.166 0.7591
Onchocerca volvulus 0.003 0.0084 0.001
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Schistosoma mansoni hypothetical protein 0.0035 0.0152 0.0338
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0976 0.4302
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0484 0.1984
Toxoplasma gondii facilitative glucose transporter GT1 0.021 0.216 0.3208
Echinococcus granulosus solute carrier family 22 0.003 0.0084 0.007
Trypanosoma brucei glucose transporter, putative 0.0065 0.0493 0.4592
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0493 0.1776
Brugia malayi 6-phosphofructokinase 0.0107 0.0976 0.4302
Loa Loa (eye worm) sugar transporter 0.021 0.216 1
Giardia lamblia Prolyl-tRNA synthetase 0.0063 0.0469 1
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.003 0.0084 0.5
Brugia malayi hypothetical protein 0.0035 0.0152 0.0338
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Echinococcus multilocularis Sugar transporter ERD6 protein 0.003 0.0084 0.0011
Echinococcus granulosus geminin 0.0166 0.166 0.7606
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0077 0.2709
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0484 0.1736
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0073 0.0589 0.0789
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0493 0.4592
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0976 0.3834
Echinococcus multilocularis geminin 0.0166 0.166 0.7591
Leishmania major glucose transporter, lmgt1 0.0065 0.0493 0.4592
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0484 0.1936
Trypanosoma brucei glucose transporter, putative 0.0065 0.0493 0.4592
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0084 0.003
Trichomonas vaginalis set domain proteins, putative 0.0233 0.2422 1
Loa Loa (eye worm) RNA binding protein 0.0125 0.1178 0.5364
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0493 0.4592
Schistosoma mansoni sugar transporter 0.003 0.0084 0.0011
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0283 0.0971
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0084 0.003
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0152 0.0338
Onchocerca volvulus 0.003 0.0084 0.001
Brugia malayi Cam kinase protein 1 0.0064 0.0484 0.1936
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0484 0.1984
Loa Loa (eye worm) hypothetical protein 0.0047 0.0283 0.1141
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0976 0.441
Plasmodium falciparum calcium-dependent protein kinase 3 0.0064 0.0484 0.0411
Brugia malayi Sugar transporter family protein 0.021 0.216 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0077 0.0786
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.021 0.216 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0199
Trichomonas vaginalis sugar transporter, putative 0.003 0.0084 0.003

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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