Detailed information for compound 651592

Basic information

Technical information
  • TDR Targets ID: 651592
  • Name: 2-[2-(4-propan-2-yloxyphenoxy)ethylsulfanyl]- 1H-benzimidazole
  • MW: 328.429 | Formula: C18H20N2O2S
  • H donors: 1 H acceptors: 1 LogP: 4.59 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(Oc1ccc(cc1)OCCSc1nc2c([nH]1)cccc2)C
  • InChi: 1S/C18H20N2O2S/c1-13(2)22-15-9-7-14(8-10-15)21-11-12-23-18-19-16-5-3-4-6-17(16)20-18/h3-10,13H,11-12H2,1-2H3,(H,19,20)
  • InChiKey: WWEDMGVOZUBXGE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[2-(4-isopropoxyphenoxy)ethylsulfanyl]-1H-benzimidazole
  • 2-[2-(4-isopropoxyphenoxy)ethylthio]-1H-benzimidazole
  • 2-{[2-(4-isopropoxyphenoxy)ethyl]sulfanyl}-1H-benzimidazole
  • AG-670/11661010
  • ZINC03902129

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus protein Wnt 2 0.0011 0.0025 0.0043
Echinococcus multilocularis ETS transcription factor Elf 1 0.0011 0.0025 0.0044
Onchocerca volvulus 0.0018 0.0059 0.0098
Echinococcus granulosus orexin receptor type 2 0.0018 0.0059 0.0103
Echinococcus multilocularis neuropeptide s receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0007 0.0008 0.0008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Brugia malayi hypothetical protein 0.0018 0.0059 0.0059
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Leishmania major C-8 sterol isomerase-like protein 0.2089 1 1
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0014 0.0038 0.0066
Echinococcus granulosus glycine receptor subunit beta 0.0014 0.0038 0.0066
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0038 0.0038
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0018 0.0059 0.0103
Schistosoma mansoni elf1 0.0011 0.0025 0.0044
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0126 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0275 0.0481
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Echinococcus granulosus nAChR subunit 0.0014 0.0038 0.0066
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0014 0.0038 0.0038
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0014 0.0038 0.0038
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0089 0.7092
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Brugia malayi G protein-coupled receptor 0.0018 0.0059 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0014 0.0038 0.0066
Echinococcus granulosus Protein Wnt-11b 0.0011 0.0025 0.0043
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0059 0.0103
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0018 0.0059 0.0103
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0014 0.0038 0.0066
Schistosoma mansoni nAChR subunit 0.0006 0.0003 0.0005
Schistosoma mansoni gabp alpha 0.0075 0.0333 0.0583
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0018 0.0059 0.0103
Echinococcus multilocularis G protein coupled receptor 139 0.0018 0.0059 0.0103
Echinococcus multilocularis neuropeptide receptor A26 0.0018 0.0059 0.0103
Loa Loa (eye worm) TYRA-2 protein 0.0018 0.0059 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0126 1
Brugia malayi Cation transporter family protein 0.0014 0.0038 0.0038
Onchocerca volvulus Neuropeptide F receptor homolog 0.0018 0.0059 0.0098
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Schistosoma mansoni hypothetical protein 0.0018 0.0059 0.0103
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0275 0.5
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0059 0.0103
Entamoeba histolytica hypothetical protein 0.0024 0.0089 0.0817
Brugia malayi G-protein coupled receptor 0.0018 0.0059 0.0059
Brugia malayi hypothetical protein 0.0006 0.0003 0.0003
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0007 0.0008 0.0008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0275 0.5
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0011 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Echinococcus multilocularis ets variant gene 4 0.0011 0.0025 0.0044
Onchocerca volvulus DNA ligase 3 homolog 0.0015 0.0045 0.0073
Loa Loa (eye worm) hypothetical protein 0.0045 0.0189 0.0189
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0116 0.1045
Brugia malayi Serotonin receptor 0.0018 0.0059 0.0059
Echinococcus multilocularis serotonin receptor 0.015 0.0694 0.1214
Echinococcus multilocularis orexin receptor type 2 0.0018 0.0059 0.0103
Schistosoma mansoni acetylcholine receptor-related 0.0006 0.0003 0.0005
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0011 0.0025 0.0044
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0059 0.0103
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0182 0.0845 0.1477
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0126 1
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0014 0.0038 0.0038
Onchocerca volvulus 0.0018 0.0059 0.0098
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Echinococcus granulosus GA binding protein alpha chain 0.0075 0.0333 0.0583
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0089 0.7092
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0059 0.0103
Schistosoma mansoni poly [ADP-ribose] polymerase 0.015 0.0692 0.121
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0182 0.0845 0.0845
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0014 0.0038 0.0038
Brugia malayi wnt family protein 0.0011 0.0025 0.0025
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0059 0.0103
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Schistosoma mansoni biogenic amine receptor 0.0018 0.0059 0.0103
Brugia malayi Fli-1 protein 0.0228 0.1067 0.1067
Loa Loa (eye worm) hypothetical protein 0.0007 0.0008 0.0008
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0025
Schistosoma mansoni nAChR subunit 0.0006 0.0003 0.0005
Brugia malayi Ets-domain containing protein 0.0011 0.0025 0.0025
Brugia malayi transcription factor E74 isoform 0.0011 0.0025 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0126 1
Echinococcus granulosus ETS transcription factor Elf 1 0.0011 0.0025 0.0044
Echinococcus granulosus G protein coupled receptor 139 0.0018 0.0059 0.0103
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0014 0.0038 0.0038
Echinococcus granulosus biogenic amine 5HT receptor 0.0412 0.1952 0.3415
Echinococcus multilocularis muscleblind protein 1 0.0155 0.0716 0.1253
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0059 0.0103
Schistosoma mansoni ets 0.0011 0.0025 0.0044
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0275 0.0481
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Echinococcus multilocularis allatostatin A receptor 0.0018 0.0059 0.0103
Onchocerca volvulus 0.0014 0.0038 0.0061
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0018 0.0059 0.0059
Onchocerca volvulus 0.0018 0.0059 0.0098
Brugia malayi Cation transporter family protein 0.0014 0.0038 0.0038
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0007 0.0008 0.0014
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0319 0.1505 0.1505
Echinococcus granulosus snurportin 1 0.0319 0.1505 0.2633
Echinococcus granulosus Protein Wnt-04 0.0011 0.0025 0.0043
Echinococcus multilocularis g-protein coupled receptor 0.0018 0.0059 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0126 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Leishmania major DNA repair protein, putative 0.0015 0.0045 0.0045
Onchocerca volvulus 0.0014 0.0038 0.0061
Loa Loa (eye worm) Wnt2 protein 0.0011 0.0025 0.0025
Brugia malayi neuropeptide F receptor 0.0018 0.0059 0.0059
Echinococcus granulosus neuropeptide receptor A26 0.0018 0.0059 0.0103
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0081 0.0361 0.0631
Schistosoma mansoni hypothetical protein 0.0018 0.0059 0.0103
Echinococcus multilocularis dro:myosuppressin receptor 0.0018 0.0059 0.0103
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0018 0.0059 0.0103
Echinococcus granulosus Protein Wnt-111 0.0011 0.0025 0.0043
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0018 0.0059 0.0103
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0018 0.0059 0.0059
Entamoeba histolytica zinc finger protein, putative 0.0032 0.0126 0.1152
Echinococcus granulosus ewsr:fli fusion protein type 0.0011 0.0025 0.0044
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0014 0.0038 0.0066
Loa Loa (eye worm) tnks protein 0.0078 0.0346 0.0346
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0007 0.0008 0.0008
Echinococcus granulosus serotonin receptor 0.0018 0.0059 0.0103
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0038 0.0066
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0018 0.0059 0.0103
Brugia malayi ORL1-like opioid receptor 0.0018 0.0059 0.0059
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0018 0.0059 0.0059
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0133 0.061 0.061
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0116 0.0116
Echinococcus multilocularis sex peptide receptor 0.0018 0.0059 0.0103
Echinococcus granulosus vesicular acetylcholine transporter 0.1197 0.5717 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0275 0.5
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0059 0.0103
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Brugia malayi hypothetical protein 0.0018 0.0059 0.0059
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0014 0.0038 0.0066
Echinococcus granulosus g protein coupled receptor 0.0018 0.0059 0.0103
Echinococcus granulosus poly adp ribose polymerase 2 0.0182 0.0845 0.1477
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Echinococcus granulosus alpha 1A adrenergic receptor 0.0018 0.0059 0.0103
Brugia malayi Ets-domain containing protein 0.0075 0.0333 0.0333
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0014 0.0038 0.0038
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Echinococcus multilocularis tankyrase 0.0083 0.0371 0.0648
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0014 0.0038 0.0066
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0182 0.0845 0.0804
Schistosoma mansoni biogenic amine (5HT) receptor 0.0412 0.1952 0.3415
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0018 0.0059 0.0103
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0116 0.0116
Echinococcus multilocularis protein Wnt 1 0.0011 0.0025 0.0043
Loa Loa (eye worm) ACC-1 protein 0.0014 0.0038 0.0038
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0007 0.0008 0.0008
Schistosoma mansoni nAChR subunit 0.0014 0.0038 0.0066
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0038 0.0038
Plasmodium vivax importin-beta 2, putative 0.003 0.0116 1
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0014 0.0038 0.0038
Onchocerca volvulus 0.0014 0.0038 0.0061
Onchocerca volvulus 0.0018 0.0059 0.0098
Echinococcus multilocularis somatostatin receptor 0.0018 0.0059 0.0103
Echinococcus multilocularis glycine receptor subunit beta 0.0014 0.0038 0.0066
Brugia malayi RE15519p 0.0018 0.0059 0.0059
Brugia malayi hypothetical protein 0.0018 0.0059 0.0059
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0059 0.0103
Schistosoma mansoni nAChR subunit 0.0014 0.0038 0.0066
Entamoeba histolytica hypothetical protein 0.0032 0.0126 0.1152
Echinococcus granulosus ETS domain containing protein Elk 1 0.0011 0.0025 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0059 0.0103
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0089 0.0045
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0007 0.0008 0.0008
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0126 1
Schistosoma mansoni nAChR subunit 0.0014 0.0038 0.0066
Echinococcus granulosus protein C ets 2 0.0011 0.0025 0.0044
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0182 0.0845 0.0804
Schistosoma mansoni histamine h1 receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Echinococcus multilocularis vesicular acetylcholine transporter 0.1197 0.5717 1
Onchocerca volvulus 0.0018 0.0059 0.0098
Schistosoma mansoni wnt related 0.0011 0.0025 0.0043
Echinococcus multilocularis wnt family member wnt11 2 0.0011 0.0025 0.0043
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0059 0.0103
Onchocerca volvulus 0.0018 0.0059 0.0098
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0006 0.0003 0.0005
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0182 0.0845 0.1477
Schistosoma mansoni tankyrase 0.0083 0.0371 0.0649
Brugia malayi Wnt-2 protein precursor 0.0011 0.0025 0.0025
Schistosoma mansoni ets-related 0.0011 0.0025 0.0044
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0014 0.0038 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Onchocerca volvulus 0.0018 0.0059 0.0098
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0059 0.0103
Loa Loa (eye worm) GABA receptor subunit 0.0007 0.0008 0.0008
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0018 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Brugia malayi hypothetical protein 0.0018 0.0059 0.0059
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0059 0.0059
Trypanosoma cruzi C-8 sterol isomerase, putative 0.2089 1 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0275 0.0481
Loa Loa (eye worm) hypothetical protein 0.0007 0.0008 0.0008
Brugia malayi putative neuropeptide receptor NPR1 0.0018 0.0059 0.0059
Echinococcus granulosus g protein coupled receptor 0.0018 0.0059 0.0103
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0007 0.0008 0.0008
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0014 0.0038 0.0066
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Brugia malayi Dopamine receptor protein 2 0.0018 0.0059 0.0059
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0006 0.0003 0.0003
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0059 0.0103
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0059 0.0103
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0275 0.0275
Brugia malayi hypothetical protein 0.0006 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Brugia malayi GnHR receptor homolog 0.0018 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Brugia malayi putative neuropeptide receptor 0.0018 0.0059 0.0059
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0006 0.0003 0.0005
Leishmania major hypothetical protein, conserved 0.0015 0.0045 0.0045
Brugia malayi excitatory GABA receptor EXP-1A 0.0014 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Echinococcus granulosus poly ADP ribose polymerase 1 0.0233 0.1092 0.1911
Echinococcus multilocularis WNT 0.0011 0.0025 0.0043
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0038 0.0066
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0038 0.0066
Schistosoma mansoni importin beta-1 0.003 0.0116 0.0204
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Brugia malayi hypothetical protein 0.0006 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0155 0.0716 0.0716
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0059 0.0103
Echinococcus granulosus poly (ADP ribose) polymerase 0.0098 0.0443 0.0774
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.1068 0.5098 0.5098
Onchocerca volvulus 0.0018 0.0059 0.0098
Schistosoma mansoni wnt related 0.0011 0.0025 0.0043
Schistosoma mansoni opsin-like receptor 0.0018 0.0059 0.0103
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0038 0.0066
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0038 0.0038
Brugia malayi WGR domain containing protein 0.0182 0.0845 0.0845
Echinococcus granulosus neuropeptide s receptor 0.0018 0.0059 0.0103
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0018 0.0059 0.0103
Schistosoma mansoni opsin-like receptor 0.0018 0.0059 0.0103
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0025 0.0044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.1197 0.5717 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Schistosoma mansoni amine GPCR 0.0018 0.0059 0.0103
Echinococcus multilocularis protein C ets 2 0.0011 0.0025 0.0044
Brugia malayi vesicular acetylcholine transporter unc-17 0.1197 0.5717 0.5717
Loa Loa (eye worm) hypothetical protein 0.0007 0.0008 0.0008
Brugia malayi G protein-coupled receptor F59B2.13 0.0018 0.0059 0.0059
Echinococcus multilocularis protein Wnt 2 0.0011 0.0025 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0126 1
Onchocerca volvulus 0.0014 0.0038 0.0061
Schistosoma mansoni neurotransmitter gated ion channel 0.0006 0.0003 0.0005
Brugia malayi Dopamine receptor protein 1 0.0018 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Brugia malayi Melatonin receptor type 1A 0.0018 0.0059 0.0059
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0059 0.0103
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0025 0.0044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Onchocerca volvulus 0.0014 0.0038 0.0061
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0018 0.0059 0.0103
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0059 0.0103
Echinococcus granulosus somatostatin receptor 0.0018 0.0059 0.0103
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0025 0.0044
Echinococcus granulosus poly (ADP ribose) polymerase 0.0049 0.0208 0.0363
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Schistosoma mansoni opsin-like receptor 0.0018 0.0059 0.0103
Brugia malayi hypothetical protein 0.0018 0.0059 0.0059
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Loa Loa (eye worm) LGC-31 protein 0.0014 0.0038 0.0038
Loa Loa (eye worm) fli-1 protein 0.0228 0.1067 0.1067
Echinococcus granulosus peptide allatostatin:somatostatin 0.0018 0.0059 0.0103
Echinococcus granulosus biogenic amine 5HT receptor 0.015 0.0694 0.1214
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0233 0.1092 0.1911
Brugia malayi Serotonin receptor 0.0018 0.0059 0.0059
Loa Loa (eye worm) melatonin receptor type 1A 0.0018 0.0059 0.0059
Schistosoma mansoni biogenic amine (5HT) receptor 0.015 0.0694 0.1214
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0075 0.0333 0.0333
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0014 0.0038 0.0066
Loa Loa (eye worm) hypothetical protein 0.2089 1 1
Brugia malayi hypothetical protein 0.0018 0.0059 0.0059
Schistosoma mansoni biogenic amine receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0006 0.0003 0.0003
Loa Loa (eye worm) D-ets-2 protein 0.0011 0.0025 0.0025
Brugia malayi follicle stimulating hormone receptor 0.0018 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0007 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.015 0.0694 0.0694
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0238 0.1114 1
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Echinococcus granulosus ETS transcription factor Elf 5 0.0011 0.0025 0.0044
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0018 0.0059 0.0098
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0275 0.0481
Schistosoma mansoni nAChR subunit 0.0014 0.0038 0.0066
Schistosoma mansoni biogenic amine receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0089 0.7092
Onchocerca volvulus 0.0018 0.0059 0.0098
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0275 0.2469
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0014 0.0038 0.0038
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0038 0.0066
Entamoeba histolytica hypothetical protein 0.0032 0.0126 0.1152
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0059 0.0103
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0059 0.0103
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0014 0.0038 0.0038
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0006 0.0003 0.0003
Onchocerca volvulus 0.0018 0.0059 0.0098
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Echinococcus multilocularis G-protein coupled receptor, putative 0.0018 0.0059 0.0103
Brugia malayi DNA-binding protein D-ETS-3 0.0011 0.0025 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0126 1
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0014 0.0038 0.0066
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0014 0.0038 0.0066
Echinococcus granulosus fmrfamide receptor 0.0018 0.0059 0.0103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0059 0.0103
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0038 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0059 0.0103
Onchocerca volvulus Putative nachr subunit 0.0014 0.0038 0.0061
Loa Loa (eye worm) hypothetical protein 0.0155 0.0716 0.0716
Loa Loa (eye worm) hypothetical protein 0.0064 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0025
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0006 0.0003 0.0003
Schistosoma mansoni vesicular acetylcholine transporter 0.1197 0.5717 1
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0015 0.0045 0.0045
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0018 0.0059 0.0059
Onchocerca volvulus 0.0018 0.0059 0.0098
Echinococcus granulosus glycine receptor subunit beta 0.0014 0.0038 0.0066
Schistosoma mansoni wnt related 0.0011 0.0025 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Brugia malayi G-protein coupled receptor 0.0018 0.0059 0.0059
Onchocerca volvulus Tankyrase homolog 0.0077 0.0341 0.0593
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0059 0.0103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0059 0.0103
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0233 0.1092 0.1911
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0038 0.0066
Plasmodium falciparum importin beta, putative 0.003 0.0116 1
Brugia malayi Wnt-4 protein precursor 0.0011 0.0025 0.0025
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0059 0.0103
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Echinococcus multilocularis snurportin 1 0.0319 0.1505 0.2633
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0059 0.0059
Echinococcus granulosus sex peptide receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0018 0.0059 0.0103
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0059 0.0103
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0038 0.0066
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0007 0.0008 0.0008
Schistosoma mansoni nAChR subunit 0.0014 0.0038 0.0066
Echinococcus multilocularis nAChR subunit 0.0014 0.0038 0.0066
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0018 0.0059 0.0103
Brugia malayi Muscleblind-like protein 0.0155 0.0716 0.0716
Echinococcus granulosus muscleblind protein 0.0155 0.0716 0.1253
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Brugia malayi RNA, U transporter 1 0.0085 0.0381 0.0381
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0018 0.0059 0.0059
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0059 0.0103
Echinococcus granulosus neuropeptide receptor 0.0018 0.0059 0.0103
Echinococcus granulosus allatostatin A receptor 0.0018 0.0059 0.0103
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0059 0.0103
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0018 0.0059 0.0059
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0014 0.0038 0.0066
Schistosoma mansoni acetylcholine receptor subunit beta 0.0006 0.0003 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0025
Echinococcus granulosus dro:myosuppressin receptor 0.0018 0.0059 0.0103
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0014 0.0038 0.0066
Echinococcus granulosus poly (ADP ribose) polymerase 0.0049 0.0208 0.0363
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Brugia malayi Dopamine receptor 0.0018 0.0059 0.0059
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0006 0.0003 0.0005
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0059 0.0103
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0059 0.0103
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0014 0.0038 0.0066
Echinococcus multilocularis wingless type MMTV integration site family 0.0011 0.0025 0.0043
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0014 0.0038 0.0038
Echinococcus granulosus tachykinin peptides receptor 99D 0.0018 0.0059 0.0103
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0412 0.1952 0.3415
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Echinococcus granulosus neuropeptide receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Onchocerca volvulus 0.0018 0.0059 0.0098
Echinococcus granulosus importin subunit beta 1 0.003 0.0116 0.0204
Echinococcus multilocularis GA binding protein alpha chain 0.0075 0.0333 0.0583
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Loa Loa (eye worm) ets-domain-containing protein 0.0011 0.0025 0.0025
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0233 0.1092 1
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0007 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.003 0.0116 0.0116
Entamoeba histolytica hypothetical protein 0.0049 0.0208 0.1902
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Echinococcus granulosus protein Wnt 1 0.0011 0.0025 0.0043
Brugia malayi hypothetical protein 0.0006 0.0003 0.0003
Echinococcus multilocularis WNT 0.0011 0.0025 0.0043
Trypanosoma brucei DNA repair protein, putative 0.0015 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0025 0.0044
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Brugia malayi Importin beta-1 subunit 0.003 0.0116 0.0116
Onchocerca volvulus 0.0018 0.0059 0.0098
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0018 0.0059 0.0059
Schistosoma mansoni nAChR subunit 0.0014 0.0038 0.0066
Brugia malayi Tachykinin-like peptides receptor 99D 0.0018 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.015 0.0694 0.0694
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0038 0.0066
Schistosoma mansoni wnt related 0.0011 0.0025 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Schistosoma mansoni neuropeptide receptor 0.0018 0.0059 0.0103
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0006 0.0003 0.0003
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0038 0.0066
Schistosoma mansoni amine GPCR 0.0018 0.0059 0.0103
Echinococcus granulosus Protein Wnt-5 0.0011 0.0025 0.0043
Echinococcus multilocularis serotonin receptor 0.015 0.0694 0.1214
Entamoeba histolytica hypothetical protein 0.0032 0.0126 0.1152
Brugia malayi hypothetical protein 0.0018 0.0059 0.0059
Trypanosoma brucei C-8 sterol isomerase, putative 0.2089 1 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Echinococcus multilocularis neuropeptide FF receptor 2 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Schistosoma mansoni myosin xvIII 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0007 0.0008 0.0008
Leishmania major importin beta-1 subunit, putative 0.0024 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0018 0.0059 0.0059
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0011 0.0025 0.0025
Echinococcus multilocularis glycine receptor subunit beta 0.0014 0.0038 0.0066
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Schistosoma mansoni adenoreceptor 0.0018 0.0059 0.0103
Onchocerca volvulus 0.0007 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Brugia malayi wnt family protein 0.0011 0.0025 0.0025
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0014 0.0038 0.0066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Echinococcus multilocularis ewsr:fli fusion protein type 0.0011 0.0025 0.0044
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0059 0.0059
Schistosoma mansoni neuropeptide receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) CWN-2 protein 0.0011 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0275 0.5
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0014 0.0038 0.0066
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0018 0.0059 0.0059
Brugia malayi Cation transporter family protein 0.0014 0.0038 0.0038
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0059 0.0059
Schistosoma mansoni amine GPCR 0.0018 0.0059 0.0103
Entamoeba histolytica hypothetical protein 0.0007 0.0008 0.0072
Echinococcus multilocularis ETS transcription factor Elf 5 0.0011 0.0025 0.0044
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0014 0.0038 0.0038
Onchocerca volvulus 0.0018 0.0059 0.0098
Schistosoma mansoni nAChR subunit 0.0014 0.0038 0.0066
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0038 0.0038
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0014 0.0038 0.0038
Brugia malayi sulfakinin receptor protein 0.0018 0.0059 0.0059
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0006 0.0003 0.0003
Echinococcus granulosus g protein coupled receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0015 0.0045 0.0045
Echinococcus granulosus 7TM GPCR rhodopsin 0.0018 0.0059 0.0103
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0059 0.0103
Schistosoma mansoni neurotransmitter gated ion channel 0.0006 0.0003 0.0005
Echinococcus granulosus WGR domain containing protein 0.0098 0.0443 0.0774
Echinococcus granulosus neuropeptide FF receptor 2 0.0018 0.0059 0.0103
Schistosoma mansoni neuropeptide receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Brugia malayi hypothetical protein 0.0018 0.0059 0.0059
Loa Loa (eye worm) wnt-4 protein 0.0011 0.0025 0.0025
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0014 0.0038 0.0066
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0014 0.0038 0.0066
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0018 0.0059 0.0103
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0014 0.0038 0.0066
Schistosoma mansoni hypothetical protein 0.0018 0.0059 0.0103
Brugia malayi neuropeptide F receptor 0.0018 0.0059 0.0059
Echinococcus granulosus hypothetical protein 0.0018 0.0059 0.0103
Entamoeba histolytica hypothetical protein 0.0032 0.0126 0.1152
Onchocerca volvulus 0.0018 0.0059 0.0098
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0007 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Schistosoma mansoni hypothetical protein 0.0011 0.0025 0.0044
Loa Loa (eye worm) ACC-1 protein 0.0014 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0003
Brugia malayi hypothetical protein 0.0018 0.0059 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0059 0.0103
Echinococcus granulosus poly (ADP ribose) polymerase 0.0049 0.0208 0.0363
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0059 0.0103
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0059 0.0103
Echinococcus multilocularis nAChR subunit 0.0007 0.0008 0.0014
Onchocerca volvulus 0.0007 0.0008 0.0009
Onchocerca volvulus 0.0018 0.0059 0.0098
Brugia malayi hypothetical protein 0.0018 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.0319 0.1505 0.2633
Echinococcus granulosus 7tm_1 domain containing protein 0.0018 0.0059 0.0103
Trypanosoma brucei poly(adp-ribose) polymerase 0.0182 0.0845 0.0845
Echinococcus granulosus nAChR subunit 0.0007 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0011 0.0025 0.0044
Schistosoma mansoni wnt-5 0.0011 0.0025 0.0043
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0018 0.0059 0.0103
Brugia malayi hypothetical protein 0.0006 0.0003 0.0003
Schistosoma mansoni ets-related 0.0228 0.1067 0.1867
Brugia malayi Ets-domain containing protein 0.0075 0.0333 0.0333
Schistosoma mansoni hypothetical protein 0.0018 0.0059 0.0103
Onchocerca volvulus 0.0018 0.0059 0.0098
Brugia malayi WGR domain containing protein 0.0233 0.1092 0.1092
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0059 0.0103
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0006 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0011 0.0025 0.0044
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0059 0.0103
Onchocerca volvulus 0.0014 0.0038 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0126 1
Brugia malayi wnt family protein 0.0011 0.0025 0.0025
Schistosoma mansoni amine GPCR 0.0018 0.0059 0.0103
Echinococcus multilocularis muscleblind protein 0.0155 0.0716 0.1253
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0006 0.0003 0.0003
Schistosoma mansoni neuropeptide f receptor 76f 0.0018 0.0059 0.0103
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0038 0.0038
Schistosoma mansoni amine GPCR 0.0018 0.0059 0.0103
Echinococcus granulosus g-protein coupled receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.015 0.0691 0.0691
Brugia malayi wnt family protein 0.0011 0.0025 0.0025
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0006 0.0003 0.0005
Schistosoma mansoni alpha-1 adrenergic receptor 0.0018 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0025
Echinococcus multilocularis importin subunit beta 1 0.003 0.0116 0.0204
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.1197 0.5717 0.5717
Schistosoma mansoni growth hormone secretagogue receptor 0.0018 0.0059 0.0103
Brugia malayi Tnks protein 0.0082 0.0367 0.0367
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Schistosoma mansoni neuropeptide receptor 0.0018 0.0059 0.0103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0059 0.0103
Echinococcus granulosus tankyrase 0.0083 0.0371 0.0648
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0059 0.0103
Brugia malayi larval opioid receptor 0.0018 0.0059 0.0059
Brugia malayi AKH receptor 0.0018 0.0059 0.0059
Schistosoma mansoni neurotransmitter gated ion channel 0.0007 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0059
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0006 0.0003 0.0005
Loa Loa (eye worm) acetylcholine receptor protein 0.0006 0.0003 0.0003

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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