Detailed information for compound 664796

Basic information

Technical information
  • TDR Targets ID: 664796
  • Name: 5-bromo-N-ethyl-N-phenylthiophene-2-sulfonami de
  • MW: 346.263 | Formula: C12H12BrNO2S2
  • H donors: 0 H acceptors: 2 LogP: 4.03 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(S(=O)(=O)c1ccc(s1)Br)c1ccccc1
  • InChi: 1S/C12H12BrNO2S2/c1-2-14(10-6-4-3-5-7-10)18(15,16)12-9-8-11(13)17-12/h3-9H,2H2,1H3
  • InChiKey: TZGQFPMHFWETNH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 5-bromo-N-ethyl-N-phenyl-thiophene-2-sulfonamide
  • 5-bromo-N-ethyl-N-phenyl-2-thiophenesulfonamide
  • ZINC00470218

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis lamin dm0 0.0061 0.0194 0.0184
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0063 0.0351
Schistosoma mansoni importin beta-1 0.0033 0.0086 0.01
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0237 0.0869 0.6266
Loa Loa (eye worm) hypothetical protein 0.0035 0.0096 0.0509
Schistosoma mansoni patched 1 0.0041 0.0119 0.0138
Entamoeba histolytica phenylalanyl-tRNA synthetase alpha subunit, putative 0.0368 0.1371 1
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0091 0.0446
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0053 0.0191
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0096 0.0086
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0069 0.0257
Leishmania major importin beta-1 subunit, putative 0.0026 0.0063 0.0207
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0053 0.0044
Schistosoma mansoni intermediate filament proteins 0.0061 0.0194 0.0225
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0096 0.01
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0053 0.0051
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0035 0.003
Echinococcus multilocularis expressed conserved protein 0.009 0.0308 0.0298
Brugia malayi Muscleblind-like protein 0.0315 0.1169 0.8492
Schistosoma mansoni cpg binding protein 0.0062 0.0199 0.023
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0348 0.1297 0.9447
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0039 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.005 0.0034
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0053 0.0191
Loa Loa (eye worm) hypothetical protein 0.0028 0.0069 0.031
Schistosoma mansoni hypothetical protein 0.004 0.0114 0.0132
Plasmodium falciparum phenylalanine--tRNA ligase alpha subunit 0.0368 0.1371 1
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0053 0.0136
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.033 0.0372
Trichomonas vaginalis set domain proteins, putative 0.0269 0.0994 0.722
Echinococcus granulosus intermediate filament protein 0.0061 0.0194 0.0214
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0107 0.0371 0.2537
Echinococcus multilocularis cpg binding protein 0.0065 0.0212 0.0203
Schistosoma mansoni hypothetical protein 0.004 0.0114 0.0132
Plasmodium falciparum phenylalanine--tRNA ligase 0.0106 0.037 0.2545
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0063 0.0351
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0107 0.0371 0.2556
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0053 0.0166
Schistosoma mansoni cpg binding protein 0.0065 0.0212 0.0246
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0069 0.0312
Trypanosoma brucei phenylalanyl-tRNA synthetase alpha chain, putative 0.0368 0.1371 1
Echinococcus granulosus muscleblind protein 0.0315 0.1169 0.1345
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0099 0.0339 0.232
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.005 0.0034
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0199 0.1273
Echinococcus multilocularis importin subunit beta 1 0.0033 0.0086 0.0077
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.1753 0.6686 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0035 0.0017
Schistosoma mansoni hypothetical protein 0.0035 0.0096 0.0111
Brugia malayi Intermediate filament tail domain containing protein 0.0061 0.0194 0.1216
Loa Loa (eye worm) hypothetical protein 0.0051 0.0155 0.0949
Brugia malayi CXXC zinc finger family protein 0.0062 0.0199 0.125
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0339 0.033
Echinococcus granulosus importin subunit beta 1 0.0033 0.0086 0.0089
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0069 0.0257
Echinococcus multilocularis dnaJ subfamily B 0.0882 0.3342 0.3336
Brugia malayi hypothetical protein 0.0035 0.0096 0.0485
Toxoplasma gondii histone lysine methyltransferase SET1 0.0119 0.0416 0.2849
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0167
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0368 0.1371 0.1589
Schistosoma mansoni hypothetical protein 0.004 0.0114 0.0132
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0339 0.0393
Loa Loa (eye worm) hypothetical protein 0.0061 0.0194 0.1239
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0035 0.0056
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0074 0.0074
Brugia malayi phenylalanyl-tRNA synthetase, mitochondrial precursor, putative 0.0106 0.037 0.2526
Echinococcus granulosus dnaJ subfamily B 0.0882 0.3342 0.3867
Schistosoma mansoni hypothetical protein 0.0034 0.0091 0.0105
Echinococcus multilocularis protein patched 0.0041 0.0119 0.011
Brugia malayi phenylalanyl (f) trna synthetase protein 1 0.0368 0.1371 1
Echinococcus multilocularis protein dispatched 1 0.0047 0.0142 0.0132
Echinococcus granulosus phenylalanyl tRNA synthetase 0.0106 0.037 0.0417
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0099 0.0339 0.23
Echinococcus granulosus snurportin 1 0.0348 0.1297 0.1493
Treponema pallidum phenylalanyl-tRNA synthetase subunit alpha 0.0368 0.1371 1
Schistosoma mansoni lamin 0.0061 0.0194 0.0225
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0053 0.0136
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.0488 0.0479
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.033 0.2231
Leishmania major phenylalanyl-tRNA synthetase alpha chain, putative 0.0368 0.1371 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0096 0.01
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0035 0.0011
Echinococcus granulosus expressed conserved protein 0.009 0.0308 0.0346
Plasmodium vivax phenylalanine--tRNA ligase alpha subunit, putative 0.0368 0.1371 1
Onchocerca volvulus 0.0062 0.0199 0.1573
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0038 0.0055
Brugia malayi AMP-binding enzyme family protein 0.0023 0.005 0.0141
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.005 0.0039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0096 0.0111
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0096 0.0086
Plasmodium falciparum phenylalanine--tRNA ligase 0.0106 0.037 0.2545
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0119 0.0127
Brugia malayi AMP-binding enzyme family protein 0.0023 0.005 0.0141
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0096 0.0111
Loa Loa (eye worm) hypothetical protein 0.006 0.019 0.1207
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.005 0.0034
Schistosoma mansoni hypothetical protein 0.0073 0.0241 0.028
Onchocerca volvulus 0.0061 0.0194 0.1525
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0119 0.0127
Chlamydia trachomatis phenylalanine--tRNA ligase subunit alpha 0.1753 0.6686 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0025 0.0018
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0025 0.0029
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0437
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0035 0.0148
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0069 0.0257
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.0469 0.0544
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0039 0.003
Toxoplasma gondii HEAT repeat-containing protein 0.0033 0.0086 0.0384
Brugia malayi intermediate filament protein 0.0061 0.0194 0.1216
Loa Loa (eye worm) hypothetical protein 0.0107 0.0371 0.2556
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0091 0.0081
Schistosoma mansoni microtubule-associated protein tau 0.226 0.8628 1
Brugia malayi cytoplasmic intermediate filament protein 0.0033 0.0086 0.0409
Schistosoma mansoni hypothetical protein 0.0882 0.3342 0.3873
Schistosoma mansoni hypothetical protein 0.0034 0.0091 0.0105
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0063 0.0351
Loa Loa (eye worm) histone methyltransferase 0.002 0.0039 0.0088
Loa Loa (eye worm) hypothetical protein 0.0315 0.1169 0.8496
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0053 0.0191
Brugia malayi Pre-SET motif family protein 0.0035 0.0096 0.0484
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.0241 0.1569
Loa Loa (eye worm) hypothetical protein 0.0034 0.0091 0.0471
Echinococcus multilocularis phenylalanyl tRNA synthetase 0.0106 0.037 0.036
Brugia malayi RNA, U transporter 1 0.0093 0.0317 0.2134
Loa Loa (eye worm) hypothetical protein 0.0073 0.0241 0.1591
Schistosoma mansoni hypothetical protein 0.0348 0.1297 0.1503
Entamoeba histolytica hypothetical protein 0.0026 0.0063 0.0207
Loa Loa (eye worm) hypothetical protein 0.0368 0.1371 1
Loa Loa (eye worm) phenylalanyl-tRNA synthetase 0.0106 0.037 0.2545
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0091 0.0446
Brugia malayi Pre-SET motif family protein 0.0237 0.0869 0.6256
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.005 0.0112
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0096 0.0456
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.005 0.0112
Entamoeba histolytica hypothetical protein 0.0035 0.0096 0.0456
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0074 0.0064
Echinococcus multilocularis microtubule associated protein 2 0.226 0.8628 0.8627
Onchocerca volvulus 0.0269 0.0994 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0167
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0339 0.0393
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0035 0.0029
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.005 0.0112
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit alpha 0.1753 0.6686 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0339 0.033
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0096 0.0086
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0086 0.0384
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0096 0.0111
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0091 0.0094
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.0488 0.0555
Leishmania major GTP-binding protein, putative 0.0024 0.0053 0.0136
Loa Loa (eye worm) hypothetical protein 0.0028 0.0069 0.031
Echinococcus multilocularis muscleblind protein 1 0.0315 0.1169 0.116
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0061 0.0194 0.1239
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0336 0.0389
Echinococcus multilocularis snurportin 1 0.0348 0.1297 0.1288
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0035 0.0025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0339 0.0382
Loa Loa (eye worm) intermediate filament protein 0.0061 0.0194 0.1239
Echinococcus granulosus phenylalanyl tRNA synthetase alpha chain B 0.0368 0.1371 0.158
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.005 0.0039
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0035 0.0056
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0106 0.037 0.2545
Loa Loa (eye worm) hypothetical protein 0.0028 0.0069 0.0312
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.033 0.0321
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.005 0.0112
Entamoeba histolytica hypothetical protein 0.0035 0.0096 0.0456
Schistosoma mansoni hypothetical protein 0.019 0.0689 0.0798
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0053 0.0136
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0368 0.1371 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.005 0.0034
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0035 0.0148
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0339 0.0393
Schistosoma mansoni ap endonuclease 0.0019 0.0035 0.0041
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.033 0.2208
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0033 0.0086 0.0434
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0025 0.0018
Onchocerca volvulus 0.0061 0.0194 0.1525
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0091 0.0081
Plasmodium vivax importin-beta 2, putative 0.0033 0.0086 0.0437
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0339 0.0382
Echinococcus granulosus lamin dm0 0.0061 0.0194 0.0214
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0086 0.0088
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0119 0.011
Entamoeba histolytica hypothetical protein 0.0035 0.0096 0.0456
Loa Loa (eye worm) hypothetical protein 0.0315 0.1169 0.8496
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0106 0.037 0.0428
Brugia malayi Importin beta-1 subunit 0.0033 0.0086 0.0412
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0086 0.0384
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.005 0.0112
Loa Loa (eye worm) hypothetical protein 0.0029 0.0074 0.0342
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.005 0.0034
Echinococcus multilocularis musashi 0.0061 0.0194 0.0184
Schistosoma mansoni hypothetical protein 0.0034 0.0091 0.0105
Echinococcus granulosus cpg binding protein 0.0065 0.0212 0.0235
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0025 0.0015
Schistosoma mansoni hypothetical protein 0.004 0.0114 0.0132
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0096 0.0111
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0035 0.0056
Trichomonas vaginalis ran, putative 0.0024 0.0053 0.0282
Echinococcus multilocularis phenylalanyl tRNA synthetase alpha chain B 0.0368 0.1371 0.1363
Plasmodium falciparum importin beta, putative 0.0033 0.0086 0.0437
Echinococcus granulosus GPCR family 2 0.0034 0.0091 0.0094
Schistosoma mansoni ap endonuclease 0.0019 0.0035 0.0041
Trypanosoma cruzi phenylalanyl-tRNA synthetase alpha chain, putative 0.0368 0.1371 1
Leishmania major hypothetical protein, conserved 0.0028 0.0069 0.0257
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0053 0.0136
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0025 0.0015
Echinococcus multilocularis muscleblind protein 0.0315 0.1169 0.116
Toxoplasma gondii phenylalanyl-tRNA synthetase alpha chain A, putative 0.0368 0.1371 1
Mycobacterium ulcerans hypothetical protein 0.0023 0.005 0.0034
Echinococcus granulosus lamin 0.0061 0.0194 0.0214
Schistosoma mansoni ran 0.0024 0.0053 0.0062
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0069 0.0257
Brugia malayi hypothetical protein 0.0028 0.0069 0.0286
Echinococcus multilocularis geminin 0.019 0.0689 0.068
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0091 0.0471
Echinococcus granulosus geminin 0.019 0.0689 0.0788
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0119 0.0684
Loa Loa (eye worm) hypothetical protein 0.0096 0.033 0.2252
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.005 0.0034
Mycobacterium leprae Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.0261 0.0963 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0069 0.0312
Entamoeba histolytica Ran family GTPase 0.0024 0.0053 0.0136
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.005 0.0034
Schistosoma mansoni ran 0.0024 0.0053 0.0062
Toxoplasma gondii Ferredoxin-fold anticodon binding domain-containing protein 0.0106 0.037 0.2503
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0063 0.0207
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0167
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0106 0.037 0.2614
Loa Loa (eye worm) hypothetical protein 0.0041 0.0119 0.0684
Entamoeba histolytica hypothetical protein 0.0035 0.0096 0.0456
Echinococcus multilocularis lamin 0.0061 0.0194 0.0184
Schistosoma mansoni phenylalanyl-tRNA synthetase mitochondrial 0.0106 0.037 0.0428
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0028 0.0005
Echinococcus multilocularis GPCR, family 2 0.0034 0.0091 0.0081
Plasmodium vivax SET domain protein, putative 0.0035 0.0096 0.0509
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0096 0.0111
Brugia malayi CHE-14 protein 0.0041 0.0119 0.066
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0119 0.0771
Brugia malayi AMP-binding enzyme family protein 0.0023 0.005 0.0141
Schistosoma mansoni hypothetical protein 0.0034 0.0091 0.0105
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0106 0.037 0.2614
Schistosoma mansoni hypothetical protein 0.0013 0.001 0.0011
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0069 0.0312
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0053 0.0136
Brugia malayi Calcitonin receptor-like protein seb-1 0.0107 0.0371 0.2537
Schistosoma mansoni hypothetical protein 0.019 0.0689 0.0798
Schistosoma mansoni lamin 0.0061 0.0194 0.0225
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit alpha 0.1753 0.6686 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.005 0.0112
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0106 0.037 0.2545
Echinococcus granulosus microtubule associated protein 2 0.226 0.8628 1
Onchocerca volvulus 0.0035 0.0096 0.0486
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0091 0.0094
Schistosoma mansoni cpg binding protein 0.0065 0.0212 0.0246
Giardia lamblia Phenylalanyl-tRNA synthetase alpha chain 0.0368 0.1371 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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