Detailed information for compound 763381

Basic information

Technical information
  • TDR Targets ID: 763381
  • Name: STOCK2S-81001
  • MW: 357.47 | Formula: C19H23N3O2S
  • H donors: 0 H acceptors: 2 LogP: 3.08 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCn1c(C)nc2c(c1=O)sc1c2cc2c(n1)CC(OC2)(C)C
  • InChi: 1S/C19H23N3O2S/c1-5-6-7-22-11(2)20-15-13-8-12-10-24-19(3,4)9-14(12)21-17(13)25-16(15)18(22)23/h8H,5-7,9-10H2,1-4H3
  • InChiKey: CYDZDGYUORYOKK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ZINC02319868

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0031 0.0359 0.0453
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0154
Toxoplasma gondii protein kinase, putative 0.0286 0.6526 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.1038 0.2314
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0309 0.039
Loa Loa (eye worm) hypothetical protein 0.0019 0.0063 0.0141
Brugia malayi jmjC domain containing protein 0.0019 0.0063 0.0141
Schistosoma mansoni protein kinase 0.0031 0.0359 0.0453
Echinococcus granulosus short transient receptor potential channel 6 0.0062 0.1113 0.1405
Brugia malayi jmjC domain containing protein 0.0019 0.0063 0.0141
Plasmodium vivax proline--tRNA ligase, putative 0.0035 0.0466 0.0405
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.1015 0.1473
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.2058 0.2597
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2058 0.2597
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.003 0.0344 0.0434
Echinococcus granulosus geminin 0.0344 0.7923 1
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7425
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.003 0.0344 0.0767
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7425
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.2994 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0063 0.0141
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0075 0.0288
Echinococcus granulosus PHD finger protein rhinoceros 0.0058 0.1015 0.1281
Schistosoma mansoni hypothetical protein 0.0035 0.0453 0.0572
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0491 0.062
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0466 0.978
Toxoplasma gondii facilitative glucose transporter GT1 0.0101 0.2058 0.3086
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0075 0.0167
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0101 0.2058 0.2597
Echinococcus granulosus transient receptor potential ion channel A 0.0091 0.1807 0.2281
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0359 0.0453
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0075 0.0288
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0843 0.1881
Echinococcus multilocularis short transient receptor potential channel 6 0.0062 0.1113 0.1405
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0069 0.0139
Schistosoma mansoni jumonji domain containing protein 0.0151 0.3266 0.4123
Schistosoma mansoni hypothetical protein 0.0344 0.7923 1
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0031 0.036 0.0298
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.6537 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0191 0.4212 0.5317
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0369 0.7425
Plasmodium falciparum calcium-dependent protein kinase 2 0.0031 0.036 0.0298
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0466 0.978
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.003 0.0344 0.0434
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0369 0.0455
Brugia malayi Transient-receptor-potential like protein 0.0035 0.0455 0.1015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0309 0.039
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.0069 0.0009
Trichomonas vaginalis set domain proteins, putative 0.023 0.5158 0.7867
Loa Loa (eye worm) hypothetical protein 0.003 0.0344 0.0767
Leishmania major glucose transporter, lmgt2 0.0031 0.0369 0.7425
Schistosoma mansoni transient receptor potential channel 0.0062 0.1113 0.1405
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0063 0.0857
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0031 0.0359 0.0801
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0369 0.7646
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0156 0.0125
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0369 0.7425
Plasmodium vivax hexose transporter 0.0101 0.2058 0.2007
Giardia lamblia PHD finger protein 15 0.0058 0.1015 0.1455
Schistosoma mansoni hypothetical protein 0.0344 0.7923 1
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0156 0.5
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0075 0.1121
Trichomonas vaginalis CAMK family protein kinase 0.0031 0.0359 0.044
Onchocerca volvulus Alhambra homolog 0.0058 0.1015 0.1456
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0359 0.0453
Brugia malayi Bromodomain containing protein 0.0058 0.1015 0.2263
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0369 0.0455
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0309 0.038
Plasmodium falciparum mitogen-activated protein kinase 2 0.0164 0.3565 0.3525
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0063 0.008
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0466 0.978
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0164 0.3565 0.3525
Loa Loa (eye worm) hypothetical protein 0.0029 0.0309 0.0689
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0843 0.1881
Echinococcus multilocularis PHD finger protein rhinoceros 0.0058 0.1015 0.1281
Brugia malayi PHD-finger family protein 0.0058 0.1015 0.2263
Loa Loa (eye worm) inositol-1 0.0036 0.0475 0.1059
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0031 0.036 0.0298
Brugia malayi jmjC domain containing protein 0.0019 0.0063 0.0141
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0063 0.008
Echinococcus multilocularis peregrin 0.0058 0.1015 0.1281
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0475 0.137
Brugia malayi jmjC domain containing protein 0.007 0.1311 0.2922
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0035 0.0455 0.0575
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0313 0.0395
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0369 0.0455
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0359 0.0453
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.2058 0.2597
Plasmodium falciparum hexose transporter 0.0101 0.2058 0.2007
Brugia malayi Cam kinase protein 1 0.0031 0.0359 0.0801
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0063 0.0857
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0075 0.0167
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0359 0.0453
Plasmodium falciparum calcium-dependent protein kinase 4 0.0031 0.036 0.0298
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0369 0.0455
Echinococcus multilocularis transient receptor potential ion channel A 0.0091 0.1807 0.2281
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7425
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0475 1
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0156 0.0093
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0384 0.1063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.6537 1
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0156 0.0197
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0075 0.0095
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.003 0.0344 0.0767
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0156 0.0197
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0019 0.0069 0.0006
Schistosoma mansoni inositol monophosphatase 0.0036 0.0475 0.0599
Plasmodium falciparum proline--tRNA ligase 0.0035 0.0466 0.0405
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0156 0.2255
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0156 0.0282
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.6537 1
Toxoplasma gondii exonuclease III APE 0.0019 0.0075 0.0018
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0031 0.036 0.0459
Plasmodium vivax CDK-related protein kinase 6, putative 0.043 1 1
Giardia lamblia Prolyl-tRNA synthetase 0.003 0.0344 0.0416
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0164 0.3565 0.5419
Plasmodium vivax SET domain protein, putative 0.0029 0.0309 0.0247
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.003 0.0344 0.0416
Loa Loa (eye worm) hypothetical protein 0.0094 0.1883 0.4199
Brugia malayi jmjC domain containing protein 0.0191 0.4212 0.9393
Plasmodium falciparum phd finger protein, putative 0.0058 0.1015 0.0958
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7425
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0156 0.0125
Schistosoma mansoni transient receptor potential channel 4 0.0094 0.1883 0.2377
Loa Loa (eye worm) hypothetical protein 0.0051 0.0843 0.1881
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0069 0.0006
Loa Loa (eye worm) PHD-finger family protein 0.0058 0.1015 0.2263
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.6537 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0359 0.0801
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0156 0.0348
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0309 0.039
Loa Loa (eye worm) hypothetical protein 0.0025 0.0206 0.046
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7425
Plasmodium falciparum calcium-dependent protein kinase 3 0.0031 0.036 0.0298
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0369 0.0455
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.6537 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0309 0.039
Leishmania major glucose transporter, lmgt3 0.0031 0.0369 0.7425
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0063 0.008
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0475 0.0619
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.6537 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2058 0.2597
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0063 0.0141
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0031 0.036 0.0459
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0156 0.0197
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0156 0.2919
Echinococcus granulosus phd:f box containing protein 0.0019 0.0063 0.008
Schistosoma mansoni protein kinase 0.0031 0.0359 0.0453
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0475 0.0619
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0491 0.062
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.2058 0.3068
Entamoeba histolytica protein kinase, putative 0.0031 0.0359 0.044
Brugia malayi Inositol-1 0.0036 0.0475 0.1059
Brugia malayi Pre-SET motif family protein 0.0202 0.4485 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0075 0.0012
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0063 0.008
Plasmodium falciparum protein kinase 7 0.0286 0.6526 0.6504
Echinococcus granulosus peregrin 0.0058 0.1015 0.1281
Plasmodium vivax hypothetical protein, conserved 0.0058 0.1015 0.0958
Schistosoma mansoni jumonji/arid domain-containing protein 0.007 0.1311 0.1654
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.4485 1
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0156 0.0197
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0031 0.0359 0.0801
Leishmania major glucose transporter, lmgt1 0.0031 0.0369 0.7425
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0063 0.008
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.2994 1
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0344 0.0434
Echinococcus multilocularis jumonji domain containing protein 0.0081 0.1565 0.1976
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.2994 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0475 1
Entamoeba histolytica hypothetical protein 0.0036 0.0491 0.0644
Schistosoma mansoni hypothetical protein 0.0058 0.1015 0.1281
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0475 0.0599
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0491 0.062
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0475 0.0619
Schistosoma mansoni transient receptor potential channel 0.0094 0.1883 0.2377
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2058 0.2597
Echinococcus multilocularis geminin 0.0344 0.7923 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.6537 1
Schistosoma mansoni glucose transport protein 0.0101 0.2058 0.2597
Loa Loa (eye worm) hypothetical protein 0.003 0.0344 0.0767
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7425
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0063 0.008
Trypanosoma cruzi hexose transporter 0.0031 0.0369 0.7646
Loa Loa (eye worm) sugar transporter 0.0101 0.2058 0.4588
Schistosoma mansoni jumonji/arid domain-containing protein 0.007 0.1311 0.1654
Schistosoma mansoni glucose transport protein 0.0101 0.2058 0.2597
Onchocerca volvulus 0.023 0.5158 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.6537 1
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0063 0.008
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0309 0.039
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0063 0.008
Loa Loa (eye worm) hypothetical protein 0.0032 0.0379 0.0846
Loa Loa (eye worm) jmjC domain-containing protein 0.012 0.2511 0.56
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0075 0.0012
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.036 0.0298
Entamoeba histolytica hypothetical protein 0.0036 0.0491 0.0644
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.6537 1
Echinococcus granulosus jumonji domain containing protein 0.0081 0.1565 0.1976
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0089 0.0021
Plasmodium falciparum calcium-dependent protein kinase 1 0.0031 0.036 0.0298
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0075 0.1121
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0475 0.0619
Echinococcus granulosus General substrate transporter 0.0087 0.1713 0.2163
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0453 0.101
Loa Loa (eye worm) jmjC domain-containing protein 0.007 0.1311 0.2922
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0359 0.0453
Loa Loa (eye worm) hypothetical protein 0.0023 0.0156 0.0348
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0359 0.0453
Treponema pallidum fructose-bisphosphate aldolase 0.0287 0.6537 1
Brugia malayi hypothetical protein 0.0036 0.0491 0.1095
Plasmodium falciparum calcium-dependent protein kinase 5 0.0031 0.036 0.0298
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0156 0.0277
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0156 0.0144
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0369 0.0455
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.003 0.0344 0.0416
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0069 0.0009
Echinococcus granulosus short transient receptor potential channel 6 0.0062 0.1113 0.1405
Echinococcus multilocularis short transient receptor potential channel 6 0.0062 0.1113 0.1405
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.6537 1
Echinococcus granulosus lysine specific demethylase 5A 0.007 0.1311 0.1654
Entamoeba histolytica hypothetical protein 0.0036 0.0491 0.0644
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0309 0.039
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0095 0.0211
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.101
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0035 0.0466 0.0623
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0475 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0075 0.0095
Schistosoma mansoni inositol monophosphatase 0.0036 0.0475 0.0599
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0843 0.1881
Schistosoma mansoni protein kinase 0.0031 0.0359 0.0453
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0475 0.0637
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0384 0.1063
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0063 0.0141
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.6537 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.1015 0.1473
Loa Loa (eye worm) hypothetical protein 0.0058 0.1015 0.2263
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0156 0.0093
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0031 0.0359 0.7192
Brugia malayi Pre-SET motif family protein 0.0029 0.0309 0.0689
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0369 0.0455
Leishmania major glucose transporter/membrane transporter D2, putative 0.0031 0.0369 0.7425
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7425
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0369 0.7425
Entamoeba histolytica hypothetical protein 0.0036 0.0491 0.0644
Loa Loa (eye worm) hypothetical protein 0.0019 0.0063 0.0141
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0069 0.0139
Schistosoma mansoni hypothetical protein 0.0036 0.0491 0.062
Trypanosoma brucei glucose transporter 2A 0.0031 0.0369 0.7425
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0309 0.039
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0369 0.7646
Schistosoma mansoni glucose transport protein 0.0101 0.2058 0.2597
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0063 0.008
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0359 0.0453
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0063 0.008
Echinococcus multilocularis lysine specific demethylase 5A 0.007 0.1311 0.1654
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0313 0.0395
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.2058 0.2597
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0075 0.0005
Schistosoma mansoni ap endonuclease 0.0019 0.0075 0.0095
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0466 0.9799
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0063 0.008
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0466 0.9799
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7425
Schistosoma mansoni transient receptor potential channel 0.0062 0.1113 0.1405
Echinococcus multilocularis General substrate transporter 0.0087 0.1713 0.2163
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0475 1
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0063 0.008
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0156 0.0277
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0475 1
Schistosoma mansoni hypothetical protein 0.0101 0.2058 0.2597
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0369 0.7646
Trypanosoma brucei glucose transporter 1E 0.0031 0.0369 0.7425
Entamoeba histolytica hypothetical protein 0.0023 0.0156 0.0125
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0475 0.0599
Echinococcus multilocularis transient receptor potential gamma protein 0.0094 0.1883 0.2377
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0031 0.0359 0.0801
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2058 0.2597
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0191 0.4212 0.5317
Brugia malayi Sugar transporter family protein 0.0101 0.2058 0.4588
Loa Loa (eye worm) hypothetical protein 0.0035 0.0455 0.1015
Leishmania major protein kinase, putative 0.0031 0.0359 0.7192
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0283 0.0357
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0058 0.1015 0.1281
Entamoeba histolytica protein kinase, putative 0.0031 0.0359 0.044
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0359 0.0453
Brugia malayi PHD-finger family protein 0.0019 0.0069 0.0154
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.003 0.0344 0.0926
Loa Loa (eye worm) hypothetical protein 0.01 0.2019 0.4502
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0063 0.008
Brugia malayi jmjC domain containing protein 0.0019 0.0063 0.0141
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0063 0.008
Plasmodium vivax calcium-dependent protein kinase, putative 0.0031 0.036 0.0298
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0095 0.0119
Echinococcus granulosus TRP transient receptor potential channel 0.0035 0.0455 0.0575
Schistosoma mansoni hypothetical protein 0.0019 0.0069 0.0087
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0344 0.0434
Schistosoma mansoni ap endonuclease 0.0019 0.0075 0.0095
Brugia malayi AF-10 protein 0.0019 0.0069 0.0154
Echinococcus granulosus transient receptor potential gamma protein 0.0094 0.1883 0.2377
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0156 0.2255
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0031 0.036 0.0459

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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