Detailed information for compound 763717

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 346.378 | Formula: C18H22N2O5
  • H donors: 1 H acceptors: 3 LogP: 1.82 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(OCCNC(=O)c1noc(c1)COc1cccc(c1)C(=O)C)C
  • InChi: 1S/C18H22N2O5/c1-12(2)23-8-7-19-18(22)17-10-16(25-20-17)11-24-15-6-4-5-14(9-15)13(3)21/h4-6,9-10,12H,7-8,11H2,1-3H3,(H,19,22)
  • InChiKey: LQZQPXMGPJSLIP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Giardia lamblia Prolyl-tRNA synthetase 0.0064 0.054 1
Echinococcus multilocularis lysyl tRNA synthetase 0.0048 0.0355 0.1602
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0041 0.0275 1
Plasmodium vivax calcium-dependent protein kinase, putative 0.0066 0.0555 0.0404
Echinococcus granulosus FTZ F1 alpha 0.0061 0.0504 0.2271
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Schistosoma mansoni RAR-like nuclear receptor 0.0061 0.0504 0.2271
Echinococcus granulosus solute carrier family 22 0.003 0.0157 0.0709
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0554 0.2499
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0554 0.2499
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0214 0.2219 1
Plasmodium falciparum calcium-dependent protein kinase 5 0.0066 0.0555 0.0404
Onchocerca volvulus 0.003 0.0157 0.025
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0061 0.0504 0.0801
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0061 0.0504 0.2271
Schistosoma mansoni nuclear hormone receptor 0.0061 0.0504 0.2271
Onchocerca volvulus 0.003 0.0157 0.025
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0048 0.0355 0.395
Giardia lamblia Lysyl-tRNA synthetase 0.0048 0.0355 0.5182
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0064 0.054 0.2432
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0064 0.054 0.0857
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0066 0.0554 0.0881
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0061 0.0504 0.2271
Onchocerca volvulus 0.0061 0.0504 0.0801
Echinococcus granulosus calcium dependent protein kinase 0.0062 0.0509 0.2294
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0064 0.054 0.1855
Echinococcus multilocularis solute carrier family 22 0.003 0.0157 0.0709
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Loa Loa (eye worm) hypothetical protein 0.0061 0.0504 0.0801
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0061 0.0504 0.2271
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0061 0.0504 0.2271
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.8107
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Echinococcus granulosus synaptic vesicle 2 protein 0.003 0.0157 0.0709
Mycobacterium ulcerans sugar transporter 0.003 0.0157 0.2954
Schistosoma mansoni thyroid hormone receptor 0.0061 0.0504 0.2271
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0157 0.025
Loa Loa (eye worm) hypothetical protein 0.0061 0.0504 0.0801
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0045 0.0324 0.146
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Echinococcus multilocularis Sugar transporter ERD6 protein 0.003 0.0157 0.0709
Trypanosoma brucei glucose transporter 1E 0.0066 0.0564 0.8107
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0061 0.0504 0.0801
Onchocerca volvulus 0.003 0.0157 0.025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0061 0.0504 0.0801
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0554 0.2499
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0355 0.1602
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0564 0.1973
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0214 0.2219 1
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0066 0.0555 0.0404
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0061 0.0504 0.2271
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0061 0.0504 0.0801
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0554 0.2499
Onchocerca volvulus 0.003 0.0157 0.025
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0061 0.0504 0.0801
Brugia malayi photoreceptor-specific nuclear receptor 0.0061 0.0504 0.0801
Echinococcus granulosus solute carrier family 22 0.003 0.0157 0.0709
Loa Loa (eye worm) hypothetical protein 0.0045 0.0324 0.0515
Plasmodium vivax lysine--tRNA ligase, putative 0.0048 0.0355 0.0201
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0564 0.1973
Entamoeba histolytica protein kinase, putative 0.0066 0.0554 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0061 0.0504 0.0801
Brugia malayi major facilitator superfamily protein 0.003 0.0157 0.025
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Loa Loa (eye worm) steroid hormone receptor 0.0061 0.0504 0.0801
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0066 0.0554 0.2499
Brugia malayi hypothetical protein 0.0045 0.0324 0.0515
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0048 0.0355 0.395
Schistosoma mansoni sugar transporter 0.003 0.0157 0.0709
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0075 0.0659 1
Onchocerca volvulus 0.003 0.0157 0.025
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.003 0.0157 0.0709
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0061 0.0504 0.0801
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0061 0.0504 0.2271
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.8107
Plasmodium vivax proline--tRNA ligase, putative 0.0075 0.0659 0.051
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0061 0.0504 0.0801
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0554 0.2499
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0064 0.054 0.9253
Loa Loa (eye worm) hypothetical protein 0.0064 0.054 0.0857
Brugia malayi Cam kinase protein 1 0.0066 0.0554 0.0881
Loa Loa (eye worm) hypothetical protein 0.0064 0.054 0.0857
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.8107
Plasmodium falciparum calcium-dependent protein kinase 1 0.0066 0.0555 0.0404
Schistosoma mansoni protein kinase 0.0066 0.0554 0.2499
Toxoplasma gondii facilitative glucose transporter GT1 0.0214 0.2219 0.3201
Onchocerca volvulus Putative transporter 0.003 0.0157 0.025
Loa Loa (eye worm) hypothetical protein 0.0052 0.0405 0.0643
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0061 0.0504 0.0801
Brugia malayi Sugar transporter family protein 0.003 0.0157 0.025
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0045 0.0324 0.146
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0659 1
Onchocerca volvulus 0.003 0.0157 0.025
Mycobacterium ulcerans integral membrane transport protein 0.003 0.0157 0.2954
Schistosoma mansoni retinoic acid receptor RXR 0.0061 0.0504 0.2271
Loa Loa (eye worm) hypothetical protein 0.0061 0.0504 0.0801
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0064 0.054 0.0857
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0061 0.0504 0.0801
Loa Loa (eye worm) hypothetical protein 0.0066 0.0554 0.0881
Loa Loa (eye worm) hypothetical protein 0.0061 0.0504 0.0801
Loa Loa (eye worm) sugar transporter 0.0214 0.2219 0.3525
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Brugia malayi Sugar transporter family protein 0.0214 0.2219 0.3525
Echinococcus granulosus Sugar transporter ERD6 protein 0.003 0.0157 0.0709
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0064 0.054 0.2432
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0346 0.3696 0.3595
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0066 0.0555 0.0617
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Echinococcus granulosus solute carrier family 22 0.003 0.0157 0.0709
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0061 0.0504 0.2271
Onchocerca volvulus Protein ultraspiracle homolog 0.0061 0.0504 0.0801
Brugia malayi steroid hormone receptor 0.0061 0.0504 0.0801
Onchocerca volvulus 0.003 0.0157 0.025
Echinococcus multilocularis solute carrier family 22 0.003 0.0157 0.0709
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0045 0.0324 0.146
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0061 0.0504 0.2271
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0564 0.8107
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0554 0.2499
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0214 0.2219 1
Schistosoma mansoni protein kinase 0.0066 0.0554 0.2499
Brugia malayi Steroid receptor seven-up type 2 0.0061 0.0504 0.0801
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0066 0.0554 0.0881
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0564 0.1973
Loa Loa (eye worm) hypothetical protein 0.0061 0.0504 0.0801
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0564 0.1973
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0355 1
Onchocerca volvulus 0.003 0.0157 0.025
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0061 0.0504 0.2271
Trichomonas vaginalis conserved hypothetical protein 0.0214 0.2219 1
Onchocerca volvulus 0.003 0.0157 0.025
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0157 0.025
Echinococcus multilocularis FTZ F1 alpha 0.0061 0.0504 0.2271
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0659 1
Schistosoma mansoni glucose transporter 0.003 0.0157 0.0709
Echinococcus granulosus lysyl tRNA synthetase 0.0048 0.0355 0.1602
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0214 0.2219 1
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0064 0.054 1
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0564 0.1973
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0564 0.1973
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0554 0.1927
Toxoplasma gondii protein kinase, putative 0.0605 0.6597 1
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0346 0.3696 0.5495
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0066 0.0555 0.0617
Brugia malayi nuclear receptor RXR 0.0045 0.0324 0.0515
Loa Loa (eye worm) hypothetical protein 0.0045 0.0324 0.0515
Echinococcus granulosus solute carrier family 22 0.003 0.0157 0.0709
Plasmodium falciparum proline--tRNA ligase 0.0075 0.0659 0.051
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0048 0.0355 0.0961
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0554 0.2499
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.8107
Plasmodium vivax hexose transporter 0.0214 0.2219 0.2094
Plasmodium falciparum mitogen-activated protein kinase 2 0.0346 0.3696 0.3595
Schistosoma mansoni sugar transporter 0.003 0.0157 0.0709
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.8107
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0061 0.0504 0.2271
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0066 0.0555 0.0617
Chlamydia trachomatis lysine--tRNA ligase 0.0048 0.0355 1
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0115 0.0183
Brugia malayi lysyl-tRNA synthetase 0.0048 0.0355 0.0565
Entamoeba histolytica protein kinase, putative 0.0066 0.0554 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0061 0.0504 0.0801
Loa Loa (eye worm) hypothetical protein 0.0048 0.0355 0.0565
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0061 0.0504 0.0801
Onchocerca volvulus 0.003 0.0157 0.025
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0061 0.0504 0.2271
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.8107
Echinococcus multilocularis calcium dependent protein kinase 0.0062 0.0509 0.2294
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.8107
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0061 0.0504 0.2271
Brugia malayi major facilitator superfamily protein 0.003 0.0157 0.025
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0061 0.0504 0.2271
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0355 0.1602
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0042 0.0289 0.0641
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0066 0.0555 0.0404
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0066 0.0554 0.7919
Plasmodium falciparum calcium-dependent protein kinase 3 0.0066 0.0555 0.0404
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0064 0.054 0.2432
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0061 0.0504 0.0801
Onchocerca volvulus 0.003 0.0157 0.025
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Plasmodium falciparum lysine--tRNA ligase 0.0048 0.0355 0.0201
Leishmania major glucose transporter, lmgt3 0.0066 0.0564 0.8107
Brugia malayi nuclear hormone receptor 0.0061 0.0504 0.0801
Leishmania major lysyl-tRNA synthetase, putative 0.0048 0.0355 0.395
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0564 0.8107
Plasmodium falciparum hexose transporter 0.0214 0.2219 0.2094
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0041 0.0275 1
Schistosoma mansoni sugar transporter 0.003 0.0157 0.0709
Echinococcus multilocularis thyroid hormone receptor alpha 0.0061 0.0504 0.2271
Echinococcus multilocularis General substrate transporter 0.0184 0.1881 0.848
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0227 0.1383
Onchocerca volvulus 0.003 0.0157 0.025
Loa Loa (eye worm) hypothetical protein 0.0045 0.0324 0.0515
Brugia malayi Nuclear hormone receptor-like 1 0.0061 0.0504 0.0801
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0061 0.0504 0.0801
Onchocerca volvulus Bile acid receptor homolog 0.0578 0.6293 1
Brugia malayi hypothetical protein 0.003 0.0157 0.025
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0061 0.0504 0.0801
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0564 0.8107
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0061 0.0504 0.0801
Schistosoma mansoni protein kinase 0.0066 0.0554 0.2499
Onchocerca volvulus 0.003 0.0157 0.025
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0157 0.025
Trypanosoma cruzi hexose transporter 0.0066 0.0564 0.8107
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0554 0.2499
Schistosoma mansoni glucose transport protein 0.0214 0.2219 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0061 0.0504 0.2271
Echinococcus multilocularis solute carrier family 22 0.003 0.0157 0.0709
Onchocerca volvulus 0.003 0.0157 0.025
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0214 0.2219 1
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.003 0.0157 0.5
Treponema pallidum prolyl-tRNA synthetase 0.0023 0.0074 0.5
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0061 0.0504 0.2271
Plasmodium vivax CDK-related protein kinase 6, putative 0.0909 1 1
Brugia malayi hypothetical protein 0.0045 0.0324 0.0515
Echinococcus granulosus General substrate transporter 0.0184 0.1881 0.848
Brugia malayi Sugar transporter family protein 0.003 0.0157 0.025
Loa Loa (eye worm) hypothetical protein 0.0045 0.0324 0.0515
Plasmodium falciparum calcium-dependent protein kinase 2 0.0066 0.0555 0.0404
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0214 0.2219 1
Schistosoma mansoni glucose transport protein 0.0214 0.2219 1
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0324 0.0515
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Onchocerca volvulus 0.003 0.0157 0.025
Onchocerca volvulus 0.003 0.0157 0.025
Schistosoma mansoni sugar transporter 0.003 0.0157 0.0709
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0064 0.054 0.2432
Echinococcus multilocularis ecdysone induced protein 78C 0.0061 0.0504 0.2271
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0061 0.0504 0.2271
Loa Loa (eye worm) hypothetical protein 0.0061 0.0504 0.0801
Loa Loa (eye worm) hypothetical protein 0.0061 0.0504 0.0801
Trypanosoma brucei glucose transporter 2A 0.0066 0.0564 0.8107
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0075 0.0659 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0564 0.8107
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0061 0.0504 0.0801
Schistosoma mansoni thyroid hormone receptor 0.0061 0.0504 0.2271
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0045 0.0324 0.146
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0075 0.0659 0.0779
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0157 0.025
Leishmania major protein kinase, putative 0.0066 0.0554 0.7919
Schistosoma mansoni coup transcription factor 0.0061 0.0504 0.2271
Plasmodium falciparum calcium-dependent protein kinase 4 0.0066 0.0555 0.0404
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0157 0.025
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0061 0.0504 0.2271
Trypanosoma brucei glucose transporter, putative 0.0066 0.0564 0.8107
Leishmania major glucose transporter/membrane transporter D2, putative 0.0066 0.0564 0.8107
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0066 0.0554 0.0881
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0324 0.0515
Brugia malayi ecdysteroid receptor 0.0578 0.6293 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0061 0.0504 0.2271
Loa Loa (eye worm) sugar transporter 0.003 0.0157 0.025
Schistosoma mansoni glucose transport protein 0.0214 0.2219 1
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0564 0.8107
Brugia malayi hypothetical protein 0.003 0.0157 0.025
Brugia malayi hypothetical protein 0.003 0.0157 0.025
Echinococcus multilocularis solute carrier family 22 0.003 0.0157 0.0709
Toxoplasma gondii lysine-tRNA ligase 0.0048 0.0355 0.0308
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0061 0.0504 0.2271
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.025
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0066 0.0555 0.0404
Leishmania major glucose transporter, lmgt2 0.0066 0.0564 0.8107
Plasmodium falciparum protein kinase 7 0.0605 0.6597 0.6542
Leishmania major glucose transporter, lmgt1 0.0066 0.0564 0.8107
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.003 0.0157 0.2954
Brugia malayi nuclear receptor NHR-88 0.0061 0.0504 0.0801
Loa Loa (eye worm) hypothetical protein 0.0045 0.0324 0.0515
Echinococcus granulosus ecdysone induced protein 78C 0.0061 0.0504 0.2271
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0061 0.0504 0.0801
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0061 0.0504 0.2271
Echinococcus multilocularis synaptic vesicle 2 protein 0.003 0.0157 0.0709
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0214 0.2219 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0045 0.0324 0.0515
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0061 0.0504 0.0801
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0355 1
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.003 0.0157 0.2954
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0564 0.8107
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0659 1
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0564 0.1973
Loa Loa (eye worm) hypothetical protein 0.0578 0.6293 1
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0048 0.0355 0.3046
Schistosoma mansoni hypothetical protein 0.0214 0.2219 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0214 0.2219 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0061 0.0504 0.0801
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0061 0.0504 0.0801

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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