Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.2063 | 0.3155 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0079 | 0.6538 | 1 |
Leishmania major | pantothenate kinase subunit, putative | 0.0079 | 0.6538 | 1 |
Trypanosoma cruzi | pantothenate kinase subunit, putative | 0.0079 | 0.6538 | 1 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0032 | 0.2063 | 0.3155 |
Wolbachia endosymbiont of Brugia malayi | parvulin-like peptidyl-prolyl isomerase, PPID | 0.001 | 0 | 0.5 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0079 | 0.6538 | 1 |
Trypanosoma brucei | pantothenate kinase subunit, putative | 0.0079 | 0.6538 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.2135 | 0.0161 |
Toxoplasma gondii | pantothenate kinase | 0.0033 | 0.2223 | 0.34 |
Giardia lamblia | Pantothenate kinase 4 | 0.0079 | 0.6538 | 0.5 |
Echinococcus multilocularis | pantothenate kinase 4 | 0.0079 | 0.6538 | 1 |
Trichomonas vaginalis | rotamase, putative | 0.0032 | 0.2135 | 0.0161 |
Loa Loa (eye worm) | pantothenate kinase | 0.0079 | 0.6538 | 0.5598 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0079 | 0.6538 | 1 |
Schistosoma mansoni | pantothenate kinase | 0.0079 | 0.6538 | 1 |
Plasmodium vivax | pantothenate kinase, putative | 0.0079 | 0.6538 | 1 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0032 | 0.2063 | 0.3155 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0079 | 0.6538 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 1 | 1 |
Entamoeba histolytica | pantothenate kinase 1, putative | 0.0079 | 0.6538 | 1 |
Schistosoma mansoni | pantothenate kinase | 0.0079 | 0.6538 | 1 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0032 | 0.2063 | 0.3155 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 1 | 1 |
Plasmodium falciparum | pantothenate kinase 1, putative | 0.0079 | 0.6538 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0046 | 0.3382 | 0.2949 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.2063 | 0.3155 |
Onchocerca volvulus | Fumble homolog | 0.0079 | 0.6538 | 0.5 |
Brugia malayi | pantothenate kinase family protein | 0.0079 | 0.6538 | 0.5598 |
Echinococcus granulosus | pantothenate kinase 4 | 0.0079 | 0.6538 | 1 |
Toxoplasma gondii | fumble protein | 0.0079 | 0.6538 | 1 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0079 | 0.6538 | 1 |
Trypanosoma cruzi | pantothenate kinase subunit, putative | 0.0079 | 0.6538 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.