Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | pantothenate kinase 1, putative | 0.0079 | 0.6538 | 1 |
Schistosoma mansoni | pantothenate kinase | 0.0079 | 0.6538 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 1 | 1 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0079 | 0.6538 | 1 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0032 | 0.2063 | 0.3155 |
Plasmodium vivax | pantothenate kinase, putative | 0.0079 | 0.6538 | 1 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0079 | 0.6538 | 1 |
Schistosoma mansoni | pantothenate kinase | 0.0079 | 0.6538 | 1 |
Loa Loa (eye worm) | pantothenate kinase | 0.0079 | 0.6538 | 0.5598 |
Trypanosoma cruzi | pantothenate kinase subunit, putative | 0.0079 | 0.6538 | 1 |
Toxoplasma gondii | fumble protein | 0.0079 | 0.6538 | 1 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0079 | 0.6538 | 1 |
Echinococcus granulosus | pantothenate kinase 4 | 0.0079 | 0.6538 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.2063 | 0.3155 |
Onchocerca volvulus | Fumble homolog | 0.0079 | 0.6538 | 0.5 |
Brugia malayi | pantothenate kinase family protein | 0.0079 | 0.6538 | 0.5598 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0046 | 0.3382 | 0.2949 |
Plasmodium falciparum | pantothenate kinase 1, putative | 0.0079 | 0.6538 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 1 | 1 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0032 | 0.2063 | 0.3155 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0032 | 0.2063 | 0.3155 |
Trypanosoma cruzi | pantothenate kinase subunit, putative | 0.0079 | 0.6538 | 1 |
Leishmania major | pantothenate kinase subunit, putative | 0.0079 | 0.6538 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.2063 | 0.3155 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0079 | 0.6538 | 1 |
Trichomonas vaginalis | rotamase, putative | 0.0032 | 0.2135 | 0.0161 |
Echinococcus multilocularis | pantothenate kinase 4 | 0.0079 | 0.6538 | 1 |
Giardia lamblia | Pantothenate kinase 4 | 0.0079 | 0.6538 | 0.5 |
Toxoplasma gondii | pantothenate kinase | 0.0033 | 0.2223 | 0.34 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.2135 | 0.0161 |
Trypanosoma brucei | pantothenate kinase subunit, putative | 0.0079 | 0.6538 | 1 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0079 | 0.6538 | 1 |
Wolbachia endosymbiont of Brugia malayi | parvulin-like peptidyl-prolyl isomerase, PPID | 0.001 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.