TDR Targets

Basic information

Technical information

TDR Targets ID: 779689
Name: 5-(3-methoxyphenyl)-1-methyl-N-[(4-propan-2-y lphenyl)methyl]imidazol-2-amine
MW: 335.443 | Formula: C21H25N3O
H donors: 1 H acceptors: 1 LogP: 4.58 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: COc1cccc(c1)c1cnc(n1C)NCc1ccc(cc1)C(C)C
InChi: 1S/C21H25N3O/c1-15(2)17-10-8-16(9-11-17)13-22-21-23-14-20(24(21)3)18-6-5-7-19(12-18)25-4/h5-12,14-15H,13H2,1-4H3,(H,22,23)
InChiKey: XHJYJJQVVBINEL-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

N-[(4-isopropylphenyl)methyl]-5-(3-methoxyphenyl)-1-methyl-imidazol-2-amine
N-[(4-isopropylphenyl)methyl]-5-(3-methoxyphenyl)-1-methyl-2-imidazolamine
(4-isopropylbenzyl)-[5-(3-methoxyphenyl)-1-methyl-imidazol-2-yl]amine
ZINC04678372

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	phosphatidylinositol 3	0.0018	0.0049	0.0069
Leishmania major	importin beta-1 subunit, putative	0.0023	0.0162	0.1665
Loa Loa (eye worm)	PHD-finger family protein	0.0035	0.0484	0.0674
Schistosoma mansoni	importin beta-1	0.0028	0.0296	0.0346
Trypanosoma cruzi	importin beta-1 subunit, putative	0.0023	0.0162	0.1665
Echinococcus granulosus	GTP binding nuclear protein Ran	0.0021	0.0108	0.0059
Brugia malayi	Bromodomain containing protein	0.0035	0.0484	0.0806
Loa Loa (eye worm)	hypothetical protein	0.0037	0.0529	0.0737
Trichomonas vaginalis	alpha-glucosidase, putative	0.0044	0.0699	0.1016
Schistosoma mansoni	chromobox protein	0.0084	0.1732	0.2362
Echinococcus granulosus	peregrin	0.0035	0.0484	0.0436
Trichomonas vaginalis	alpha-glucosidase, putative	0.0044	0.0699	0.1016
Schistosoma mansoni	jumonji domain containing protein	0.0092	0.1923	0.2629
Trichomonas vaginalis	set domain proteins, putative	0.0286	0.6886	1
Schistosoma mansoni	alpha glucosidase	0.0044	0.0699	0.0912
Trypanosoma cruzi	phosphatidylinositol 3-related kinase, putative	0.0018	0.0049	0.051
Entamoeba histolytica	Ran family GTPase	0.0021	0.0108	0.1116
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0046	0.0768	0.1115
Entamoeba histolytica	hypothetical protein	0.0023	0.0162	0.1665
Schistosoma mansoni	hypothetical protein	0.0019	0.0071	0.003
Trypanosoma brucei	phosphatidylinositol 3-related kinase, putative	0.0018	0.0049	0.051
Loa Loa (eye worm)	jmjC domain-containing protein	0.0073	0.144	0.2007
Echinococcus multilocularis	lysosomal alpha glucosidase	0.0197	0.4607	0.458
Schistosoma mansoni	hypothetical protein	0.0297	0.7175	1
Trichomonas vaginalis	conserved hypothetical protein	0.0047	0.0789	0.1145
Trichomonas vaginalis	chromobox protein, putative	0.0084	0.1732	0.2516
Brugia malayi	Pre-SET motif family protein	0.0036	0.0505	0.0842
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0018	0.0049	0.0072
Trichomonas vaginalis	chromobox protein, putative	0.0084	0.1732	0.2516
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0043	0.0687	0.0997
Trypanosoma cruzi	hypothetical protein, conserved	0.0044	0.0699	0.7208
Trichomonas vaginalis	PIKK family atypical protein kinase	0.004	0.0615	0.0893
Echinococcus granulosus	lysine specific demethylase 5A	0.0043	0.0673	0.0626
Trichomonas vaginalis	alpha-glucosidase, putative	0.0044	0.0699	0.1016
Schistosoma mansoni	hypothetical protein	0.0035	0.0484	0.0609
Trichomonas vaginalis	sucrase-isomaltase, putative	0.0044	0.0699	0.1016
Trypanosoma brucei	GTP-binding nuclear protein rtb2, putative	0.0021	0.0108	0.1116
Entamoeba histolytica	FKBP-rapamycin associated protein (FRAP), putative	0.0054	0.097	1
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0036	0.0505	0.0458
Leishmania major	phosphatidylinositol 3-related kinase, putative	0.0018	0.0049	0.051
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0043	0.0673	0.0875
Brugia malayi	latrophilin 2 splice variant baaae	0.0041	0.0635	0.1059
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0032	0.0404	0.0587
Echinococcus multilocularis	importin subunit beta 1	0.0028	0.0296	0.0248
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0018	0.0049	0.0072
Leishmania major	target of rapamycin (TOR) kinase 2, putative	0.0054	0.097	1
Brugia malayi	Glycosyl hydrolases family 31 protein	0.0044	0.0699	0.1166
Brugia malayi	chromobox protein homolog 3	0.0047	0.0789	0.1315
Trichomonas vaginalis	alpha-glucosidase, putative	0.0044	0.0699	0.1016
Trichomonas vaginalis	PIKK family atypical protein kinase	0.004	0.0615	0.0893
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0054	0.097	0.1617
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0036	0.0505	0.0639
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0043	0.0687	0.0997
Leishmania major	target of rapamycin (TOR) kinase 1, putative	0.0054	0.097	1
Leishmania major	target of rapamycin kinase (TOR) kinase 3	0.0043	0.0688	0.709
Trichomonas vaginalis	neutral alpha-glucosidase ab precursor, putative	0.0044	0.0699	0.1016
Echinococcus granulosus	jumonji domain containing protein	0.0049	0.0836	0.079
Loa Loa (eye worm)	glycosyl hydrolase family 31 protein	0.0197	0.4607	0.642
Trichomonas vaginalis	maltase-glucoamylase, putative	0.0044	0.0699	0.1016
Schistosoma mansoni	ran	0.0021	0.0108	0.0082
Echinococcus multilocularis	GPCR, family 2	0.0019	0.0071	0.0022
Schistosoma mansoni	hypothetical protein	0.0019	0.0071	0.003
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0029	0.0333	0.0483
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0505	0.0704
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.006	0.1122	0.1869
Echinococcus multilocularis	jumonji domain containing protein	0.0049	0.0836	0.079
Loa Loa (eye worm)	heterochromatin protein 1	0.0084	0.1732	0.2414
Plasmodium falciparum	importin beta, putative	0.0028	0.0296	0.5002
Brugia malayi	Heterochromatin protein 1	0.0084	0.1732	0.2887
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0635	0.0885
Loa Loa (eye worm)	GTP-binding nuclear protein RAN/TC4	0.0021	0.0108	0.0151
Echinococcus multilocularis	PHD finger protein rhinoceros	0.0035	0.0484	0.0436
Plasmodium vivax	SET domain protein, putative	0.0036	0.0505	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0035	0.0484	0.0703
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0036	0.0505	0.0458
Schistosoma mansoni	ran	0.0021	0.0108	0.0082
Schistosoma mansoni	cellular tumor antigen P53	0.006	0.1109	0.1487
Trichomonas vaginalis	conserved hypothetical protein	0.0047	0.0789	0.1145
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0484	0.0674
Brugia malayi	GTP-binding nuclear protein RAN/TC4	0.0021	0.0108	0.018
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0437	0.0635
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0251	0.6	0.8362
Giardia lamblia	PHD finger protein 15	0.0035	0.0484	0.4355
Echinococcus multilocularis	chromobox protein 1	0.0084	0.1732	0.1691
Loa Loa (eye worm)	jmjC domain-containing protein	0.0043	0.0673	0.0937
Echinococcus multilocularis	peregrin	0.0035	0.0484	0.0436
Brugia malayi	jmjC domain containing protein	0.0043	0.0673	0.1121
Echinococcus multilocularis	Mitotic checkpoint protein PRCC, C terminal	0.0152	0.3465	0.3433
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0019	0.0071	0.0119
Plasmodium vivax	importin-beta 2, putative	0.0028	0.0296	0.4731
Onchocerca volvulus	Alhambra homolog	0.0035	0.0484	0.0702
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0054	0.097	0.1409
Trypanosoma brucei	phosphatidylinositol 3-kinase, putative	0.0018	0.0049	0.051
Trichomonas vaginalis	PIKK family atypical protein kinase	0.004	0.0615	0.0893
Echinococcus multilocularis	FKBP12 rapamycin complex associated protein	0.0054	0.097	0.0925
Leishmania major	alpha glucosidase II subunit, putative	0.0044	0.0699	0.7208
Echinococcus multilocularis	neutral alpha glucosidase AB	0.0044	0.0699	0.0653
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0018	0.0049	0.0072
Onchocerca volvulus		0.006	0.1109	0.1611
Toxoplasma gondii	target of rapamycin (TOR), putative	0.004	0.0615	0.8577
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0296	0.0412
Schistosoma mansoni	chromobox protein	0.0084	0.1732	0.2362
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0437	0.0635
Schistosoma mansoni	hypothetical protein	0.0019	0.0071	0.003
Trypanosoma cruzi	target of rapamycin kinase 3	0.0043	0.0688	0.709
Loa Loa (eye worm)	glycosyl hydrolase family 31 protein	0.0044	0.0699	0.0975
Echinococcus multilocularis	lysosomal alpha glucosidase	0.0197	0.4607	0.458
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0029	0.0332	0.0482
Trypanosoma brucei	Phosphatidylinositol 3-kinase tor1	0.0054	0.097	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0043	0.0687	0.0997
Trichomonas vaginalis	ran, putative	0.0021	0.0108	0.0157
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0164	0.3777	0.3746
Trichomonas vaginalis	importin beta-1, putative	0.0023	0.0162	0.0235
Echinococcus granulosus	importin subunit beta 1	0.0028	0.0296	0.0248
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0023	0.0162	0.0235
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.006	0.1122	0.1563
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0054	0.097	0.1409
Echinococcus granulosus	GPCR family 2	0.0019	0.0071	0.0022
Brugia malayi	Latrophilin receptor protein 2	0.0019	0.0071	0.0119
Onchocerca volvulus	Heterochromatin protein 1 homolog	0.0051	0.088	0.1278
Trichomonas vaginalis	chromobox protein, putative	0.0051	0.088	0.1278
Schistosoma mansoni	hypothetical protein	0.0019	0.0071	0.003
Trypanosoma brucei	glucosidase, putative	0.0044	0.0699	0.7208
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0032	0.0413	0.0599
Plasmodium falciparum	phd finger protein, putative	0.0035	0.0484	1
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0019	0.0071	0.0022
Echinococcus granulosus	chromobox protein 1	0.0084	0.1732	0.1691
Echinococcus multilocularis	snurportin 1	0.0297	0.7175	0.7161
Trypanosoma brucei	phosphatidylinositol 4-kinase, putative	0.0054	0.097	1
Schistosoma mansoni	bromodomain-containing nuclear protein 1 brd1	0.0035	0.0484	0.0609
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0071	0.0099
Brugia malayi	PHD-finger family protein	0.0035	0.0484	0.0806
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0018	0.0049	0.0072
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0019	0.0071	0.0022
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0036	0.0505	0.0639
Loa Loa (eye worm)	hypothetical protein	0.006	0.1109	0.1546
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0029	0.0332	0.0482
Schistosoma mansoni	hypothetical protein	0.0041	0.0635	0.0822
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0019	0.0071	0.0022
Trichomonas vaginalis	alpha-glucosidase, putative	0.0044	0.0699	0.1016
Trypanosoma brucei	FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative	0.0023	0.016	0.1652
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0043	0.0687	0.0997
Brugia malayi	Importin beta-1 subunit	0.0028	0.0296	0.0493
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor2	0.0054	0.097	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1126	0.1569
Schistosoma mansoni	thyroid hormone receptor	0.0164	0.3777	0.5231
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0297	0.7175	1
Echinococcus granulosus	chromobox protein 1	0.0084	0.1732	0.1691
Leishmania major	phosphatidylinositol 3-kinase, putative	0.0018	0.0049	0.051
Toxoplasma gondii	HEAT repeat-containing protein	0.0028	0.0296	0.3176
Onchocerca volvulus		0.005	0.0857	0.1244
Onchocerca volvulus		0.0114	0.2489	0.3615
Echinococcus granulosus	Mitotic checkpoint protein PRCC C terminal	0.0152	0.3465	0.3433
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0035	0.0471	0.0424
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0032	0.0413	0.0599
Brugia malayi	RNA, U transporter 1	0.0079	0.1607	0.2678
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0054	0.097	0.1409
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0043	0.0687	0.0997
Onchocerca volvulus		0.0286	0.6886	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.004	0.0615	0.0893
Toxoplasma gondii	PHD-finger domain-containing protein	0.0035	0.0484	0.635
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0023	0.0162	0.0235
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0018	0.0049	0.0082
Echinococcus multilocularis	tumor protein p63	0.0408	1	1
Trypanosoma brucei	importin beta-1 subunit, putative	0.0028	0.0296	0.3051
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0029	0.0333	0.0483
Trichomonas vaginalis	chromobox protein, putative	0.0051	0.088	0.1278
Trichomonas vaginalis	neutral alpha-glucosidase ab precursor, putative	0.0044	0.0699	0.1016
Toxoplasma gondii	PHD-finger domain-containing protein	0.0035	0.0484	0.635
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0036	0.0505	0.6714
Giardia lamblia	GTOR	0.0054	0.097	1
Trypanosoma brucei	phosphatidylinositol 3-kinase tor, putative	0.0026	0.024	0.2474
Echinococcus multilocularis	GTP binding nuclear protein Ran	0.0021	0.0108	0.0059
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0043	0.0673	0.0875
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0021	0.0108	0.1116
Trypanosoma brucei	importin beta-1 subunit, putative	0.0028	0.0296	0.3051
Brugia malayi	Glycosyl hydrolases family 31 protein	0.0197	0.4607	0.7678
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0018	0.0049	0.0072
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0029	0.0333	0.0483
Echinococcus multilocularis	chromobox protein 1	0.0084	0.1732	0.1691
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor1	0.0054	0.097	1
Echinococcus granulosus	histone lysine methyltransferase setb	0.0036	0.0505	0.0458
Loa Loa (eye worm)	phosphatidylinositol 3	0.0054	0.097	0.1352
Trypanosoma cruzi	hypothetical protein, conserved	0.0044	0.0699	0.7208
Onchocerca volvulus		0.0037	0.0529	0.0768
Entamoeba histolytica	phosphatidylinositol3-kinaseTor2, putative	0.0054	0.097	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0036	0.0514	0.0747
Echinococcus granulosus	FKBP12 rapamycin complex associated protein	0.0054	0.097	0.0925
Echinococcus granulosus	lysosomal alpha glucosidase	0.0197	0.4607	0.458
Schistosoma mansoni	thyroid hormone receptor	0.0164	0.3777	0.5231
Trichomonas vaginalis	PIKK family atypical protein kinase	0.004	0.0615	0.0893
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0021	0.0108	0.1116
Echinococcus granulosus	snurportin 1	0.0297	0.7175	0.7161
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0115	0.2528	0.2491
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0029	0.0333	0.0483
Brugia malayi	jmjC domain containing protein	0.0115	0.2528	0.4214
Trichomonas vaginalis	PIKK family atypical protein kinase	0.004	0.0615	0.0893
Trichomonas vaginalis	PIKK family atypical protein kinase	0.004	0.0615	0.0893
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0029	0.0332	0.0482
Echinococcus multilocularis	lysine specific demethylase 5A	0.0043	0.0673	0.0626
Schistosoma mansoni	ataxia telangiectasia mutated (atm)-related	0.0054	0.097	0.1292
Echinococcus granulosus	neutral alpha glucosidase AB	0.0044	0.0699	0.0653
Loa Loa (eye worm)	hypothetical protein	0.006	0.1122	0.1563
Brugia malayi	Calcitonin receptor-like protein seb-1	0.006	0.1122	0.1869
Schistosoma mansoni	alpha-glucosidase	0.0169	0.3907	0.5414
Entamoeba histolytica	glycosyl hydrolase, family 31 protein	0.0044	0.0699	0.7208
Leishmania major	GTP-binding protein, putative	0.0021	0.0108	0.1116
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0789	0.1099
Trypanosoma brucei	target of rapamycin kinase 3, putative	0.0043	0.0688	0.709
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0036	0.0505	0.0639
Entamoeba histolytica	glycosyl hydrolase, family 31 protein	0.0044	0.0699	0.7208
Schistosoma mansoni	hypothetical protein	0.0152	0.3465	0.4794
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0115	0.2528	0.2491
Toxoplasma gondii	glycosyl hydrolase, family 31 protein	0.0044	0.0699	1
Echinococcus granulosus	PHD finger protein rhinoceros	0.0035	0.0484	0.0436
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0032	0.0413	0.0599
Trypanosoma cruzi	phosphatidylinositol 3-related kinase, putative	0.0018	0.0049	0.051
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0032	0.0404	0.0587
Schistosoma mansoni	alpha-glucosidase	0.0169	0.3907	0.5414
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0019	0.0071	0.0099
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0019	0.0071	0.0022
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.005	0.0857	0.1133
Plasmodium vivax	hypothetical protein, conserved	0.0035	0.0484	0.9458
Brugia malayi	Pre-SET motif family protein	0.0251	0.6	1
Onchocerca volvulus	Heterochromatin protein 1 homolog	0.0047	0.0789	0.1145

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 779689