Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | vesicular acetylcholine transporter | 0.1612 | 1 | 1 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.0101 | 0.0101 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0047 | 0.0059 | 0.0059 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0974 | 0.5949 | 0.5949 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.0101 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0101 | 0.0042 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0187 | 0.0945 | 0.0945 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0059 | 0.0059 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0 | 0.5 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0974 | 0.5949 | 0.5 |
Onchocerca volvulus | Vesicular acetylcholine transporter homolog | 0.1612 | 1 | 1 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.0101 | 0.0042 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.0101 | 0.0101 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.0101 | 0.0101 |
Schistosoma mansoni | vesicular acetylcholine transporter | 0.1612 | 1 | 1 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0047 | 0.0059 | 0.0059 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.0101 | 0.0101 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0187 | 0.0945 | 0.0945 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0047 | 0.0059 | 0.0059 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0 | 0.5 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0047 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0498 | 0.2922 | 0.288 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0059 | 0.0059 |
Echinococcus multilocularis | vesicular acetylcholine transporter | 0.1612 | 1 | 1 |
Loa Loa (eye worm) | vesicular acetylcholine transporter unc-17 | 0.1612 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0974 | 0.5949 | 0.5925 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0047 | 0.0059 | 0.0059 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0974 | 0.5949 | 0.5 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.0101 | 0.0101 |
Schistosoma mansoni | hypothetical protein | 0.0288 | 0.1588 | 0.1588 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0974 | 0.5949 | 0.5 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0059 | 0.0059 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0059 | 0.0059 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.