Detailed information for compound 811070

Basic information

Technical information
  • TDR Targets ID: 811070
  • Name: N,N-dipropylbenzamide
  • MW: 205.296 | Formula: C13H19NO
  • H donors: 0 H acceptors: 1 LogP: 3.17 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCN(C(=O)c1ccccc1)CCC
  • InChi: 1S/C13H19NO/c1-3-10-14(11-4-2)13(15)12-8-6-5-7-9-12/h5-9H,3-4,10-11H2,1-2H3
  • InChiKey: XDIWDRFZCSZPTO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 14657-86-4
  • CBMicro_007632
  • ST042568
  • BIM-0007606.P001
  • Benzamide, N,N-dipropyl-
  • ZINC00029524
  • Dipropylbenzamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0577 0.4363 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0893 0.697 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0577 0.4363 0.4363
Schistosoma mansoni hypothetical protein 0.0167 0.097 0.2159
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0918 0.2037
Echinococcus multilocularis thyroid hormone receptor alpha 0.0577 0.4363 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0256 0.1706 0.2408
Loa Loa (eye worm) hypothetical protein 0.0256 0.1706 0.1706
Schistosoma mansoni nuclear receptor 0.0256 0.1706 0.3858
Brugia malayi nuclear receptor NHR-88 0.0577 0.4363 0.4363
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0256 0.1706 0.1396
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0577 0.4363 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0577 0.4363 1
Brugia malayi steroid hormone receptor 0.1215 0.9628 0.9628
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0577 0.4363 0.6241
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0577 0.4363 0.4363
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0577 0.4363 0.4363
Loa Loa (eye worm) MBCTL1 0.0053 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0577 0.4363 0.4363
Brugia malayi ecdysone receptor 0.0256 0.1706 0.1706
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0322 0.2253 0.5123
Loa Loa (eye worm) DR-78 0.0256 0.1706 0.1706
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0577 0.4363 0.4363
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0256 0.1706 0.3858
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0577 0.4363 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0577 0.4363 1
Brugia malayi Nuclear hormone receptor-like 1 0.0577 0.4363 0.4363
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0577 0.4363 0.4363
Echinococcus multilocularis nuclear receptor nhr 48 0.0256 0.1706 0.3858
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0577 0.4363 0.4363
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0577 0.4363 1
Schistosoma mansoni zinc finger protein 0.0256 0.1706 0.3858
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0577 0.4363 0.4363
Brugia malayi nuclear hormone receptor 0.0256 0.1706 0.1706
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0577 0.4363 0.4363
Brugia malayi nuclear receptor RXR 0.0256 0.1706 0.1706
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0577 0.4363 0.6241
Loa Loa (eye worm) steroid hormone receptor 0.1215 0.9628 0.9628
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0577 0.4363 0.6241
Brugia malayi nuclear receptor NHR-88 0.0256 0.1706 0.1706
Schistosoma mansoni coup transcription factor 0.0577 0.4363 1
Schistosoma mansoni RAR-like nuclear receptor 0.0577 0.4363 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0256 0.1706 0.1396
Brugia malayi orphan nuclear receptor NR2E1 0.0256 0.1706 0.1706
Schistosoma mansoni nuclear receptor 0.0256 0.1706 0.3858
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0577 0.4363 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0577 0.4363 0.4363
Onchocerca volvulus 0.0256 0.1706 0.1396
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0577 0.4363 0.6241
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0577 0.4363 1
Loa Loa (eye worm) hypothetical protein 0.0256 0.1706 0.1706
Brugia malayi hypothetical protein 0.0322 0.2253 0.2253
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0322 0.2253 0.3197
Onchocerca volvulus 0.0256 0.1706 0.1396
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0256 0.1706 0.3858
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0577 0.4363 0.6241
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0322 0.2253 0.5123
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0577 0.4363 1
Echinococcus granulosus nuclear receptor nhr 48 0.0256 0.1706 0.2408
Schistosoma mansoni steroid hormone receptor ad4bp 0.0577 0.4363 1
Loa Loa (eye worm) hypothetical protein 0.0322 0.2253 0.2253
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0577 0.4363 1
Schistosoma mansoni alpha-glucosidase 0.0138 0.0733 0.1611
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0577 0.4363 0.4363
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0577 0.4363 0.4363
Loa Loa (eye worm) hypothetical protein 0.0053 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0256 0.1706 0.1706
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0577 0.4363 1
Onchocerca volvulus Bile acid receptor homolog 0.126 1 1
Brugia malayi Nuclear hormone receptor E75 0.0256 0.1706 0.1706
Echinococcus granulosus geminin 0.0167 0.097 0.1348
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0577 0.4363 0.4363
Schistosoma mansoni retinoic acid receptor RXR 0.0577 0.4363 1
Loa Loa (eye worm) hypothetical protein 0.0256 0.1706 0.1706
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0322 0.2253 0.5123
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0577 0.4363 0.4363
Echinococcus multilocularis FTZ F1 alpha 0.0577 0.4363 1
Loa Loa (eye worm) hypothetical protein 0.0256 0.1706 0.1706
Schistosoma mansoni hypothetical protein 0.0167 0.097 0.2159
Loa Loa (eye worm) hypothetical protein 0.0577 0.4363 0.4363
Brugia malayi tailless protein 0.0256 0.1706 0.1706
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0577 0.4363 0.4363
Brugia malayi Steroid receptor seven-up type 2 0.0577 0.4363 0.4363
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0256 0.1706 0.1706
Loa Loa (eye worm) hypothetical protein 0.0256 0.1706 0.1706
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0577 0.4363 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0577 0.4363 0.6241
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0577 0.4363 0.4363
Loa Loa (eye worm) hypothetical protein 0.0322 0.2253 0.2253
Loa Loa (eye worm) hypothetical protein 0.126 1 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0577 0.4363 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0256 0.1706 0.1706
Loa Loa (eye worm) nuclear hormone receptor 0.0256 0.1706 0.1706
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0256 0.1706 0.3858
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0918 0.1271
Brugia malayi hypothetical protein 0.0256 0.1706 0.1706
Loa Loa (eye worm) hypothetical protein 0.0256 0.1706 0.1706
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0577 0.4363 0.6241
Echinococcus granulosus Nuclear hormone receptor HR96 0.0256 0.1706 0.2408
Schistosoma mansoni hypothetical protein 0.0285 0.1948 0.4419
Brugia malayi nuclear hormone receptor 0.0577 0.4363 0.4363
Brugia malayi nuclear hormone receptor family member nhr-6 0.0256 0.1706 0.1706
Schistosoma mansoni nuclear receptor nhr-48 0.0256 0.1706 0.3858
Loa Loa (eye worm) hypothetical protein 0.0256 0.1706 0.1706
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0036 0.0036
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0918 0.2037
Loa Loa (eye worm) hypothetical protein 0.0577 0.4363 0.4363
Loa Loa (eye worm) hypothetical protein 0.0322 0.2253 0.2253
Brugia malayi conserved hypotetical protein 0.0256 0.1706 0.1706
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0185 0.1121 0.2506
Brugia malayi hypothetical protein 0.0322 0.2253 0.2253
Loa Loa (eye worm) nuclear receptor NHR-67 0.0256 0.1706 0.1706
Loa Loa (eye worm) hypothetical protein 0.0256 0.1706 0.1706
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0577 0.4363 0.4363
Loa Loa (eye worm) hypothetical protein 0.0577 0.4363 0.4363
Brugia malayi Nuclear hormone receptor-like 1 0.0322 0.2253 0.2253
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0577 0.4363 0.4153
Brugia malayi nuclear receptor RXR 0.0322 0.2253 0.2253
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0918 0.0918
Brugia malayi Nuclear hormone receptor E75 0.0256 0.1706 0.1706
Echinococcus multilocularis geminin 0.0167 0.097 0.2159
Schistosoma mansoni thyroid hormone receptor 0.0577 0.4363 1
Schistosoma mansoni alpha-glucosidase 0.0138 0.0733 0.1611
Schistosoma mansoni thyroid hormone receptor 0.0577 0.4363 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0256 0.1706 0.3858
Loa Loa (eye worm) hypothetical protein 0.0256 0.1706 0.1706
Loa Loa (eye worm) hypothetical protein 0.0577 0.4363 0.4363
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0185 0.1121 0.1564
Loa Loa (eye worm) hypothetical protein 0.0256 0.1706 0.1706
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0577 0.4363 0.4363
Loa Loa (eye worm) hypothetical protein 0.0256 0.1706 0.1706
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0256 0.1706 0.3858
Onchocerca volvulus Protein ultraspiracle homolog 0.0577 0.4363 0.4153
Brugia malayi nuclear receptor NHR-67 0.0256 0.1706 0.1706
Echinococcus granulosus ecdysone induced protein 78C 0.0577 0.4363 0.6241
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0256 0.1706 0.3858
Loa Loa (eye worm) hypothetical protein 0.0322 0.2253 0.2253
Loa Loa (eye worm) hypothetical protein 0.0256 0.1706 0.1706
Brugia malayi Nuclear hormone receptor-like 1 0.0322 0.2253 0.2253
Onchocerca volvulus 0.0577 0.4363 0.4153
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0256 0.1706 0.2408
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0577 0.4363 0.4363
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0256 0.1706 0.1706
Loa Loa (eye worm) hypothetical protein 0.0322 0.2253 0.2253
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0577 0.4363 0.4363
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0256 0.1706 0.3858
Brugia malayi hypothetical protein 0.0256 0.1706 0.1706
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0322 0.2253 0.2253
Schistosoma mansoni nuclear hormone receptor 0.0577 0.4363 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0577 0.4363 0.4363
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0577 0.4363 0.4363
Echinococcus granulosus Nuclear hormone receptor HR96 0.0256 0.1706 0.2408
Echinococcus granulosus FTZ F1 alpha 0.0577 0.4363 0.6241
Loa Loa (eye worm) hypothetical protein 0.0577 0.4363 0.4363
Loa Loa (eye worm) hypothetical protein 0.0577 0.4363 0.4363
Schistosoma mansoni nuclear hormone receptor 0.0256 0.1706 0.3858
Schistosoma mansoni nuclear hormone receptor 0.0256 0.1706 0.3858
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0918 0.0918

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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