Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | 4-hydroxyphenylpyruvate dioxygenase | 0.1906 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1906 | 0 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.1906 | 0 | 0.5 |
Mycobacterium ulcerans | glyoxalase GloA | 0.1906 | 0 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.1906 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.1906 | 0 | 0.5 |
Toxoplasma gondii | glyoxalase I, putative | 0.1906 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.1906 | 0 | 0.5 |
Trypanosoma cruzi | lactoylglutathione lyase-like protein, putative | 0.1906 | 0 | 0.5 |
Plasmodium falciparum | glyoxalase I | 0.1906 | 0 | 0.5 |
Plasmodium vivax | glyoxalase I, putative | 0.1906 | 0 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.1906 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.1906 | 0 | 0.5 |
Plasmodium vivax | glyoxalase I, putative | 0.1906 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.1906 | 0 | 0.5 |
Mycobacterium tuberculosis | Cadmium inducible protein CadI | 0.1906 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.1906 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1906 | 0 | 0.5 |
Plasmodium falciparum | glyoxalase I | 0.1906 | 0 | 0.5 |
Mycobacterium tuberculosis | Conserved protein TB27.3 | 0.1906 | 0 | 0.5 |
Onchocerca volvulus | Putative protein | 1.2981 | 1 | 1 |
Toxoplasma gondii | glyoxalase family protein | 0.1906 | 0 | 0.5 |
Trypanosoma cruzi | lactoylglutathione lyase-like protein, putative | 0.1906 | 0 | 0.5 |
Schistosoma mansoni | gynecophoral canal protein | 0.1906 | 0 | 0.5 |
Leishmania major | glyoxalase I,trypanothione-dependent glyoxalase I | 0.1906 | 0 | 0.5 |
Loa Loa (eye worm) | 4-hydroxyphenylpyruvate dioxygenase | 1.2981 | 1 | 1 |
Mycobacterium ulcerans | biphenyl-2,3-diol 1,2-dioxygenase | 0.1906 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.1906 | 0 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.1906 | 0 | 0.5 |
Mycobacterium ulcerans | glyoxalase GloA | 0.1906 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.