Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.0174 | 0.6916 | 0.5699 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0224 | 1 | 1 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.0174 | 0.6916 | 0.5699 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0062 | 0 | 0.5 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0174 | 0.6916 | 0.6916 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.0108 | 0.283 | 0.283 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0224 | 1 | 1 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0174 | 0.6916 | 0.5699 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0108 | 0.283 | 0.283 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0224 | 1 | 1 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0224 | 1 | 1 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0224 | 1 | 1 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0174 | 0.6916 | 0.6916 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0174 | 0.6916 | 0.5699 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0174 | 0.6916 | 0.5699 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0224 | 1 | 0.5 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0174 | 0.6916 | 0.5699 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0224 | 1 | 0.5 |
Echinococcus granulosus | proteasome prosome macropain | 0.0224 | 1 | 1 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0224 | 1 | 1 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0174 | 0.6916 | 0.6916 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Mycobacterium ulcerans | proteasome PrcB | 0.0224 | 1 | 0.5 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0224 | 1 | 1 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0108 | 0.283 | 0.283 |
Brugia malayi | proteasome subunit beta type 1 | 0.0174 | 0.6916 | 0.6916 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0224 | 1 | 1 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0174 | 0.6916 | 0.5699 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0224 | 1 | 1 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0108 | 0.283 | 0.283 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0108 | 0.283 | 0.283 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0224 | 1 | 1 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0224 | 1 | 1 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0174 | 0.6916 | 0.5699 |
Brugia malayi | proteasome subunit beta type 2 | 0.0108 | 0.283 | 0.283 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0174 | 0.6916 | 0.6916 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0224 | 1 | 1 |
Giardia lamblia | Proteasome subunit beta type 1 | 0.0174 | 0.6916 | 0.5699 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0062 | 0 | 0.5 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.0174 | 0.6916 | 0.5699 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0224 | 1 | 1 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.