Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Alpha-L-fucosidase family protein | 0.0253 | 0.5252 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0074 | 0.0108 | 0.0549 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0184 | 0.3287 | 0.532 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0107 | 0.1053 | 0.5343 |
Schistosoma mansoni | alpha-glucosidase | 0.0159 | 0.2549 | 0.1471 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0107 | 0.1053 | 0.5343 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0184 | 0.3287 | 0.532 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0111 | 0.1176 | 0.5967 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0074 | 0.0108 | 0.0549 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.0418 | 1 | 1 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.0418 | 1 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0107 | 0.1053 | 0.5343 |
Trichomonas vaginalis | beta-glucosidase, putative | 0.0138 | 0.1971 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0154 | 0.2411 | 0.1037 |
Schistosoma mansoni | thyroid hormone receptor | 0.0154 | 0.2411 | 0.1037 |
Trichomonas vaginalis | glycoside hydrolases, putative | 0.0138 | 0.1971 | 1 |
Schistosoma mansoni | alpha-l-fucosidase | 0.0253 | 0.5252 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0159 | 0.2549 | 0.1471 |
Onchocerca volvulus | 0.0107 | 0.1054 | 1 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0107 | 0.1053 | 0.5343 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0111 | 0.1176 | 0.5967 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0184 | 0.3287 | 0.1521 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0184 | 0.3287 | 0.1521 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0184 | 0.3287 | 0.1521 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0107 | 0.1053 | 0.5343 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0154 | 0.2411 | 0.0415 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0107 | 0.1053 | 0.5343 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.0253 | 0.5252 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.