Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | alpha-L-fucosidase | 0.0293 | 0.5355 | 1 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.0484 | 1 | 0.5 |
Schistosoma mansoni | beta-galactosidase | 0.0088 | 0.038 | 0.071 |
Entamoeba histolytica | beta-galactosidase, putative | 0.0072 | 0 | 0.5 |
Trichomonas vaginalis | beta-galactosidase, putative | 0.0139 | 0.1615 | 0.3198 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.038 | 0.071 |
Brugia malayi | Alpha-L-fucosidase family protein | 0.0293 | 0.5355 | 1 |
Trichomonas vaginalis | glycoside hydrolases, putative | 0.016 | 0.2144 | 1 |
Brugia malayi | manba-prov protein | 0.0115 | 0.1033 | 0.1929 |
Trichomonas vaginalis | beta-glucosidase, putative | 0.016 | 0.2144 | 1 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.0484 | 1 | 1 |
Trichomonas vaginalis | glycoside hydrolase, putative | 0.0139 | 0.1615 | 0.3198 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0139 | 0.1615 | 0.3198 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.038 | 0.071 |
Schistosoma mansoni | alpha-l-fucosidase | 0.0293 | 0.5355 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.