Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) | 0.0037 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1443 | 0.1443 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.029 | 0.929 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0076 | 0.1443 | 0.1443 |
Schistosoma mansoni | amidase | 0.0309 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.017 | 0.489 | 0.489 |
Echinococcus multilocularis | tar DNA binding protein | 0.0076 | 0.1443 | 0.1443 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0043 | 0.0227 | 0.0227 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1443 | 0.1443 |
Loa Loa (eye worm) | carboxylesterase | 0.0043 | 0.0227 | 0.0227 |
Echinococcus multilocularis | acetylcholinesterase | 0.017 | 0.489 | 0.489 |
Brugia malayi | TAR-binding protein | 0.0076 | 0.1443 | 0.1443 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0043 | 0.0227 | 0.0227 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0181 | 0.5288 | 1 |
Brugia malayi | hypothetical protein | 0.0043 | 0.0227 | 0.0227 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0037 | 0 | 0.5 |
Brugia malayi | Muscleblind-like protein | 0.0145 | 0.3971 | 0.3971 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0227 | 0.0227 |
Echinococcus multilocularis | sn1 specific diacylglycerol lipase beta | 0.029 | 0.929 | 0.929 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0037 | 0 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.017 | 0.489 | 0.489 |
Trichomonas vaginalis | lipase containing protein, putative | 0.029 | 0.929 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.4689 | 0.4689 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0227 | 0.0227 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0037 | 0 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0076 | 0.1443 | 0.1443 |
Echinococcus granulosus | geminin | 0.0165 | 0.4689 | 0.4689 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0309 | 1 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0043 | 0.0227 | 0.0227 |
Plasmodium vivax | glutamyl-tRNA(Gln) amidotransferase subunit A, putative | 0.0037 | 0 | 0.5 |
Echinococcus multilocularis | geminin | 0.0165 | 0.4689 | 0.4689 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.489 | 0.489 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0309 | 1 | 1 |
Echinococcus granulosus | muscleblind protein | 0.0145 | 0.3971 | 0.3971 |
Brugia malayi | Carboxylesterase family protein | 0.0043 | 0.0227 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0227 | 0.0227 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0043 | 0.0227 | 0.0227 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0043 | 0.0227 | 0.0227 |
Echinococcus multilocularis | carboxylesterase 5A | 0.017 | 0.489 | 0.489 |
Brugia malayi | Carboxylesterase family protein | 0.0043 | 0.0227 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0309 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1443 | 0.1443 |
Echinococcus granulosus | sn1 specific diacylglycerol lipase beta | 0.029 | 0.929 | 0.929 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0309 | 1 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0043 | 0.0227 | 0.0227 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.029 | 0.929 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.017 | 0.489 | 0.489 |
Leishmania major | hypothetical protein, conserved | 0.029 | 0.929 | 1 |
Onchocerca volvulus | 0.029 | 0.929 | 1 | |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0076 | 0.1443 | 0.1443 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.489 | 0.489 |
Trypanosoma brucei | lipase domain protein, putative | 0.029 | 0.929 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.017 | 0.489 | 0.489 |
Schistosoma mansoni | gliotactin | 0.0043 | 0.0227 | 0.0227 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0043 | 0.0227 | 0.043 |
Loa Loa (eye worm) | carboxylesterase | 0.0043 | 0.0227 | 0.0227 |
Brugia malayi | Carboxylesterase family protein | 0.017 | 0.489 | 0.489 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0227 | 0.0227 |
Plasmodium falciparum | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0037 | 0 | 0.5 |
Trypanosoma brucei | lipase domain protein, putative | 0.029 | 0.929 | 1 |
Echinococcus granulosus | neuroligin | 0.0043 | 0.0227 | 0.0227 |
Echinococcus multilocularis | acetylcholinesterase | 0.017 | 0.489 | 0.489 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0043 | 0.0227 | 0.0227 |
Brugia malayi | Carboxylesterase family protein | 0.0043 | 0.0227 | 0.0227 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1443 | 0.1443 |
Brugia malayi | Carboxylesterase family protein | 0.0043 | 0.0227 | 0.0227 |
Echinococcus multilocularis | muscleblind protein | 0.0145 | 0.3971 | 0.3971 |
Trichomonas vaginalis | lipase containing protein, putative | 0.029 | 0.929 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.017 | 0.489 | 0.489 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0043 | 0.0227 | 0.0227 |
Loa Loa (eye worm) | RNA binding protein | 0.0076 | 0.1443 | 0.1443 |
Loa Loa (eye worm) | lipase | 0.029 | 0.929 | 0.929 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0076 | 0.1443 | 0.1443 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0227 | 0.0227 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1443 | 0.1443 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0043 | 0.0227 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0227 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.3971 | 0.3971 |
Echinococcus granulosus | acetylcholinesterase | 0.017 | 0.489 | 0.489 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0181 | 0.5288 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.3971 | 0.3971 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.017 | 0.489 | 0.489 |
Schistosoma mansoni | acetylcholinesterase | 0.0043 | 0.0227 | 0.0227 |
Echinococcus multilocularis | neuroligin | 0.0043 | 0.0227 | 0.0227 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0309 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.4689 | 0.4689 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0043 | 0.0227 | 0.043 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0309 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0227 | 0.0227 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0043 | 0.0227 | 0.0227 |
Mycobacterium leprae | PROBABLE AMIDASE AMIC (AMINOHYDROLASE) | 0.0037 | 0 | 0.5 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0145 | 0.3971 | 0.3971 |
Brugia malayi | RNA binding protein | 0.0076 | 0.1443 | 0.1443 |
Brugia malayi | Lipase family protein | 0.029 | 0.929 | 0.929 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0043 | 0.0227 | 0.0227 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.