Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0869 | 0.0869 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0287 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0287 | 1 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0152 | 0.444 | 0.444 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0257 | 0.8744 | 0.8744 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.093 | 0.093 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 0.093 | 0.093 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0287 | 1 | 1 |
Onchocerca volvulus | 0.0287 | 1 | 1 | |
Plasmodium vivax | amine transporter, putative | 0.0044 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0287 | 1 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0059 | 0.0617 | 0.0617 |
Brugia malayi | Fli-1 protein | 0.023 | 0.7645 | 0.7645 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0257 | 0.8744 | 0.8744 |
Schistosoma mansoni | thyroid hormone receptor | 0.0287 | 1 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0135 | 0.3773 | 0.3773 |
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 0.093 | 0.093 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.444 | 0.444 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0135 | 0.3773 | 0.3773 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0152 | 0.444 | 0.444 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0089 | 0.187 | 0.187 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.093 | 0.093 |
Brugia malayi | nuclear receptor RXR | 0.0135 | 0.3773 | 0.3773 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0135 | 0.3773 | 0.3773 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.093 | 0.093 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0287 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0135 | 0.3773 | 0.3773 |
Toxoplasma gondii | hypothetical protein | 0.0044 | 0 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0175 | 0.0175 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0287 | 1 | 1 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 | 0.0062 | 0.076 | 0.1125 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0287 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Plasmodium vivax | hypothetical protein, conserved | 0.0044 | 0 | 0.5 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0257 | 0.8744 | 0.8744 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0287 | 1 | 1 |
Echinococcus multilocularis | serotonin transporter | 0.0257 | 0.8744 | 0.8744 |
Loa Loa (eye worm) | serotonin transporter b | 0.0257 | 0.8744 | 0.8744 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Brugia malayi | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0287 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.093 | 0.093 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0076 | 0.1319 | 0.1319 |
Echinococcus multilocularis | jun protein | 0.0089 | 0.187 | 0.187 |
Echinococcus granulosus | jun protein | 0.0089 | 0.187 | 0.187 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0076 | 0.1319 | 0.1319 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.444 | 0.444 |
Brugia malayi | hypothetical protein | 0.0152 | 0.444 | 0.444 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0287 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0287 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0287 | 1 | 1 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 | 0.0087 | 0.1771 | 0.4783 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0135 | 0.3773 | 0.3773 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0135 | 0.3773 | 0.3773 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0287 | 1 | 1 |
Brugia malayi | Ets-domain containing protein | 0.0076 | 0.1319 | 0.1319 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0087 | 0.1771 | 0.4783 |
Plasmodium falciparum | amino acid transporter, putative | 0.0044 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0284 | 0.9873 | 0.9873 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0184 | 0.576 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.093 | 0.093 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0152 | 0.444 | 0.444 |
Schistosoma mansoni | jun-related protein | 0.0072 | 0.1185 | 0.1185 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0287 | 1 | 1 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0076 | 0.1319 | 0.1319 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.177 | 0.177 |
Brugia malayi | nuclear hormone receptor | 0.0135 | 0.3773 | 0.3773 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.093 | 0.093 |
Brugia malayi | ecdysone receptor | 0.0135 | 0.3773 | 0.3773 |
Schistosoma mansoni | nuclear receptor | 0.0135 | 0.3773 | 0.3773 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0135 | 0.3773 | 0.3773 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0287 | 1 | 1 |
Onchocerca volvulus | 0.0257 | 0.8744 | 0.8744 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0175 | 0.0175 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0287 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0287 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0135 | 0.3773 | 0.3773 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.1185 | 0.1185 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.093 | 0.093 |
Schistosoma mansoni | nuclear hormone receptor | 0.0287 | 1 | 1 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0044 | 0 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0135 | 0.3773 | 0.3773 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0135 | 0.3773 | 0.3773 |
Brugia malayi | nuclear hormone receptor | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0135 | 0.3773 | 0.3773 |
Brugia malayi | RNA binding protein | 0.0066 | 0.093 | 0.093 |
Onchocerca volvulus | 0.0135 | 0.3773 | 0.3773 | |
Schistosoma mansoni | nuclear hormone receptor | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0287 | 1 | 1 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0059 | 0.0617 | 0.0617 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0287 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0287 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0175 | 0.0175 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0287 | 1 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0044 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0287 | 1 | 1 |
Mycobacterium ulcerans | carbon monoxide dehydrogenase | 0.0122 | 0.3212 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0175 | 0.0175 |
Trichomonas vaginalis | aldehyde oxidase, putative | 0.0184 | 0.576 | 0.5 |
Brugia malayi | nuclear receptor NHR-88 | 0.0287 | 1 | 1 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0135 | 0.3773 | 0.3773 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.093 | 0.093 |
Schistosoma mansoni | nuclear hormone receptor | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0052 | 0.0337 | 0.0337 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0287 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0287 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-67 | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 1 | 1 |
Onchocerca volvulus | 0.007 | 0.1084 | 0.1084 | |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0152 | 0.444 | 0.444 |
Brugia malayi | bZIP transcription factor family protein | 0.0089 | 0.187 | 0.187 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0287 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0175 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.8744 | 0.8744 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0152 | 0.444 | 0.444 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0089 | 0.187 | 0.187 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 1 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0135 | 0.3773 | 0.3773 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0044 | 0 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0287 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0175 | 0.0175 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0175 | 0.0175 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0287 | 1 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | DR-78 | 0.0135 | 0.3773 | 0.3773 |
Schistosoma mansoni | thyroid hormone receptor | 0.0287 | 1 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0135 | 0.3773 | 0.3773 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0257 | 0.8744 | 0.8744 |
Brugia malayi | nuclear receptor NHR-88 | 0.0135 | 0.3773 | 0.3773 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0059 | 0.0617 | 0.0617 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0287 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0135 | 0.3773 | 0.3773 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0287 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0175 | 0.0175 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0287 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0287 | 1 | 1 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0257 | 0.8744 | 0.5 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0287 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.093 | 0.093 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0287 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.444 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.8744 | 0.8744 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0257 | 0.8744 | 0.8744 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0287 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0152 | 0.444 | 0.444 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0184 | 0.576 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0287 | 1 | 1 |
Plasmodium falciparum | transporter, putative | 0.0044 | 0 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0287 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0287 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0135 | 0.3773 | 0.3773 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.444 | 0.444 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0287 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0287 | 1 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0052 | 0.0337 | 0.0337 |
Brugia malayi | hypothetical protein | 0.007 | 0.1084 | 0.1084 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.093 | 0.093 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0175 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.444 | 0.444 |
Onchocerca volvulus | 0.0135 | 0.3773 | 0.3773 | |
Schistosoma mansoni | gabp alpha | 0.0076 | 0.1319 | 0.1319 |
Echinococcus granulosus | serotonin transporter | 0.0257 | 0.8744 | 0.8744 |
Toxoplasma gondii | hypothetical protein | 0.0044 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0152 | 0.444 | 0.444 |
Brugia malayi | tailless protein | 0.0135 | 0.3773 | 0.3773 |
Schistosoma mansoni | nuclear receptor | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3773 | 0.3773 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | fli-1 protein | 0.023 | 0.7645 | 0.7645 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (large chain) | 0.0087 | 0.1771 | 1 |
Brugia malayi | steroid hormone receptor | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.8744 | 0.8744 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0287 | 1 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0135 | 0.3773 | 0.3773 |
Brugia malayi | conserved hypotetical protein | 0.0135 | 0.3773 | 0.3773 |
Schistosoma mansoni | coup transcription factor | 0.0287 | 1 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0044 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0152 | 0.444 | 0.444 |
Schistosoma mansoni | ets-related | 0.023 | 0.7645 | 0.7645 |
Brugia malayi | nuclear receptor RXR | 0.0152 | 0.444 | 0.444 |
Schistosoma mansoni | zinc finger protein | 0.0135 | 0.3773 | 0.3773 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0287 | 1 | 1 |
Brugia malayi | Ets-domain containing protein | 0.0076 | 0.1319 | 0.1319 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase medium chain CoxM | 0.0062 | 0.076 | 0.1125 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0287 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.