Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glycogen debranching enzyme, putative | 0.0126 | 0.0966 | 0.3764 |
Giardia lamblia | 4-alpha-glucanotransferase, amylo-alpha-1,6-glucosidase | 0.0126 | 0.0966 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0405 | 0.863 | 1 |
Echinococcus multilocularis | glycogen debranching enzyme | 0.0126 | 0.0966 | 0.0713 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0454 | 1 | 1 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.0383 | 0.8036 | 0.5 |
Trichomonas vaginalis | glycogen debranching enzyme, putative | 0.0126 | 0.0966 | 0.3764 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0101 | 0.0273 | 0.5 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0168 | 0.2115 | 1 |
Echinococcus granulosus | fucosidase alpha L 1 tissue | 0.0383 | 0.8036 | 0.7981 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0101 | 0.0273 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0405 | 0.863 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0454 | 1 | 1 |
Schistosoma mansoni | alpha-l-fucosidase | 0.0383 | 0.8036 | 0.9312 |
Brugia malayi | Amylo-alpha-1,6-glucosidase family protein | 0.0126 | 0.0966 | 0.0713 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0101 | 0.0273 | 0.5 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.0383 | 0.8036 | 0.7981 |
Trypanosoma brucei | glucosidase, putative | 0.0101 | 0.0273 | 0.5 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0454 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0162 | 0.196 | 0.2271 |
Entamoeba histolytica | glycogen debranching enzyme, putative | 0.0126 | 0.0966 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.0966 | 0.0713 |
Onchocerca volvulus | 0.036 | 0.7395 | 0.5 | |
Brugia malayi | Alpha-L-fucosidase family protein | 0.0383 | 0.8036 | 0.7981 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0168 | 0.2115 | 1 |
Echinococcus granulosus | glycogen debranching enzyme | 0.0126 | 0.0966 | 0.0713 |
Schistosoma mansoni | alpha glucosidase | 0.0101 | 0.0273 | 0.0316 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.0383 | 0.8036 | 0.7981 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0454 | 1 | 1 |
Toxoplasma gondii | Amylo-alpha-1,6-glucosidase | 0.0126 | 0.0966 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.