Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0 | 0.5 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0067 | 0.0448 | 1 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0055 | 0.0136 | 0.0202 |
Echinococcus multilocularis | geminin | 0.0335 | 0.7191 | 0.7191 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0136 | 0.0202 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0055 | 0.0136 | 0.0136 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0199 | 0.3778 | 0.5606 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0067 | 0.0448 | 1 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0055 | 0.0136 | 0.0136 |
Loa Loa (eye worm) | MBCTL1 | 0.0055 | 0.0136 | 0.0202 |
Loa Loa (eye worm) | STAT protein | 0.0317 | 0.6738 | 1 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0067 | 0.0448 | 0.0448 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0199 | 0.3778 | 0.5606 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0189 | 0.352 | 0.352 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0067 | 0.0448 | 0.1031 |
Toxoplasma gondii | 1,3-beta-glucan synthase component protein | 0.0222 | 0.4346 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0 | 0.5 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0189 | 0.352 | 0.352 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0 | 0.5 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0199 | 0.3778 | 0.5 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0199 | 0.3778 | 0.3778 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0051 | 0.0075 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0067 | 0.0448 | 0.0665 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0051 | 0.0051 | 0.0075 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0067 | 0.0448 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0292 | 0.6102 | 0.8486 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0447 | 1 | 1 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0317 | 0.6738 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0335 | 0.7191 | 1 |
Echinococcus granulosus | geminin | 0.0335 | 0.7191 | 0.7191 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0049 | 0 | 0.5 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0447 | 1 | 1 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0199 | 0.3778 | 0.5253 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0055 | 0.0136 | 0.0136 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0447 | 1 | 1 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0067 | 0.0448 | 0.0623 |
Schistosoma mansoni | hypothetical protein | 0.0335 | 0.7191 | 1 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0067 | 0.0448 | 0.0448 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0199 | 0.3778 | 0.3778 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0055 | 0.0136 | 0.0136 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0067 | 0.0448 | 1 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0055 | 0.0136 | 0.019 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0067 | 0.0448 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.