Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | glycosyltransferase-related | 0.0051 | 0.1834 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0026 | 0.06 | 0.224 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0026 | 0.06 | 0.0365 |
Entamoeba histolytica | heat shock transcription factor, putative | 0.0071 | 0.2773 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0018 | 0.0244 | 0.0244 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0018 | 0.0244 | 0.0244 |
Echinococcus multilocularis | zinc finger transcription factor gli2 | 0.022 | 1 | 1 |
Entamoeba histolytica | heat shock transcription factor, putative | 0.0071 | 0.2773 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0018 | 0.0244 | 0.0244 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0026 | 0.06 | 0.224 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0035 | 0.1077 | 0.1077 |
Loa Loa (eye worm) | glycosyl transferase family 8 protein | 0.0051 | 0.1834 | 0.1834 |
Echinococcus multilocularis | glycosyltransferase protein LARGE2 | 0.0049 | 0.1755 | 0.1549 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0535 | 0.0535 |
Echinococcus granulosus | Glycosyl transferase family 8 | 0.0051 | 0.1834 | 0.163 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0035 | 0.1077 | 0.1077 |
Echinococcus multilocularis | glycosyltransferase protein LARGE2 | 0.0049 | 0.1755 | 0.1549 |
Echinococcus multilocularis | Glycosyltransferase protein LARGE1 | 0.0038 | 0.1196 | 0.0976 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0038 | 0.1196 | 0.0976 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0024 | 0.0535 | 0.0535 |
Brugia malayi | hypothetical protein | 0.0026 | 0.06 | 0.06 |
Entamoeba histolytica | heat shock transcription factor, putative | 0.0071 | 0.2773 | 1 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0244 | 0.0244 |
Echinococcus multilocularis | glycosyltransferase protein LARGE2 | 0.0049 | 0.1755 | 0.1549 |
Onchocerca volvulus | Heat shock factor protein 2 homolog | 0.0071 | 0.2773 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1077 | 0.1077 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0026 | 0.06 | 0.0365 |
Echinococcus granulosus | zinc finger transcription factor gli2 | 0.022 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0035 | 0.1077 | 0.1077 |
Loa Loa (eye worm) | zinc finger protein | 0.022 | 1 | 1 |
Brugia malayi | Glycosyl transferase family 8 protein | 0.0051 | 0.1834 | 0.1834 |
Echinococcus multilocularis | Glycosyl transferase, family 8 | 0.0051 | 0.1834 | 0.163 |
Echinococcus granulosus | Glycosyltransferase protein LARGE1 | 0.0038 | 0.1196 | 0.0976 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.2773 | 0.2773 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0535 | 0.183 |
Echinococcus granulosus | glycosyltransferase protein LARGE2 | 0.0049 | 0.1755 | 0.1549 |
Brugia malayi | HSF-type DNA-binding domain containing protein | 0.0071 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0018 | 0.0244 | 0.0244 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.