Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | cyclin dependent kinase 7 (cdk7), putative | 0.0036 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0157 | 0.7243 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0132 | 0.5741 | 0.5788 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0157 | 0.7243 | 1 |
Echinococcus multilocularis | dual specificity | 0.0157 | 0.7243 | 0.7302 |
Plasmodium falciparum | MO15-related protein kinase | 0.0036 | 0 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0132 | 0.5741 | 0.5788 |
Echinococcus multilocularis | serine:threonine protein kinase haspin | 0.0202 | 0.9918 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0132 | 0.5741 | 0.5788 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0132 | 0.5741 | 0.5788 |
Echinococcus multilocularis | dual specificity | 0.0157 | 0.7243 | 0.7302 |
Echinococcus multilocularis | dual specificity | 0.0157 | 0.7243 | 0.7302 |
Echinococcus granulosus | acetylcholinesterase | 0.0132 | 0.5741 | 0.5788 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0157 | 0.7243 | 0.7302 |
Loa Loa (eye worm) | haspin protein kinase | 0.0202 | 0.9918 | 0.9918 |
Loa Loa (eye worm) | carboxylesterase | 0.0132 | 0.5741 | 0.5741 |
Brugia malayi | Dual-specificity tyrosine-phosphorylation regulated kinase 2 | 0.0157 | 0.7243 | 0.7302 |
Echinococcus multilocularis | acetylcholinesterase | 0.0132 | 0.5741 | 0.5788 |
Trypanosoma brucei | dual specificity tyrosine-phosphorylation-regulated kinase 2, putative | 0.0157 | 0.7243 | 1 |
Echinococcus granulosus | serine:threonine protein kinase haspin | 0.0202 | 0.9918 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0132 | 0.5741 | 0.5741 |
Echinococcus granulosus | serine:threonine protein kinase haspin | 0.0202 | 0.9918 | 1 |
Brugia malayi | hypothetical protein | 0.0202 | 0.9918 | 1 |
Echinococcus granulosus | serine:threonine protein kinase haspin | 0.0202 | 0.9918 | 1 |
Loa Loa (eye worm) | haspin protein kinase | 0.0202 | 0.9918 | 0.9918 |
Echinococcus granulosus | acetylcholinesterase | 0.0132 | 0.5741 | 0.5788 |
Echinococcus granulosus | dual specificity | 0.0157 | 0.7243 | 0.7302 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0157 | 0.7243 | 1 |
Giardia lamblia | Kinase, CMGC DYRK | 0.0157 | 0.7243 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0202 | 0.9918 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0157 | 0.7243 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0157 | 0.7243 | 1 |
Trypanosoma cruzi | dual specificity tyrosine-phosphorylation-regulated kinase 2, putative | 0.0157 | 0.7243 | 1 |
Leishmania major | protein kinase, putative,dual-specificity protein kinase, putative | 0.0157 | 0.7243 | 1 |
Brugia malayi | GSG2 | 0.0202 | 0.9918 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0157 | 0.7243 | 1 |
Echinococcus granulosus | dual specificity | 0.0157 | 0.7243 | 0.7302 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.5741 | 0.5741 |
Plasmodium vivax | serine/threonine protein kinase KIN, putative | 0.0036 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0157 | 0.7243 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0132 | 0.5741 | 0.5788 |
Echinococcus granulosus | dual specificity | 0.0157 | 0.7243 | 0.7302 |
Echinococcus granulosus | carboxylesterase 5A | 0.0132 | 0.5741 | 0.5788 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK2 protein kinase | 0.0157 | 0.7243 | 0.7243 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0157 | 0.7243 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase DYRK2, putative | 0.0157 | 0.7243 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase haspin | 0.0202 | 0.9918 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.5741 | 0.5741 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.