TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 332.353 | Formula: C20H16N2O3
H donors: 1 H acceptors: 3 LogP: 3.81 Rotable bonds: 5
Rule of 5 violations (Lipinski): 1
SMILES: CCCOc1ccc(cc1)N=C(C1=C(O)c2c(C1=O)cccc2)C#N
InChi: 1S/C20H16N2O3/c1-2-11-25-14-9-7-13(8-10-14)22-17(12-21)18-19(23)15-5-3-4-6-16(15)20(18)24/h3-10,23H,2,11H2,1H3
InChiKey: FQGGQVHBNARGFL-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0145	0.3265	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0145	0.3265	0.41
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0145	0.3265	1
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0023	0.0029
Onchocerca volvulus	Cathepsin L homolog	0.0145	0.3265	1
Entamoeba histolytica	cysteine proteinase, putative	0.0079	0.1337	0.4054
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0145	0.3265	1
Echinococcus granulosus	cysteine protease	0.0079	0.1337	0.1317
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0145	0.3265	1
Brugia malayi	Papain family cysteine protease containing protein	0.0034	0.0023	0.0029
Entamoeba histolytica	cysteine protease, putative	0.0079	0.1337	0.4054
Echinococcus multilocularis	cysteine protease	0.0145	0.3265	0.3249
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0145	0.3265	0.3249
Leishmania major	cathepsin L-like protease	0.0145	0.3265	1
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0046	0.0383	0.0483
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0383	0.0361
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.01	0.195	0.2438
Onchocerca volvulus		0.0145	0.3265	1
Plasmodium vivax	vivapain-3	0.0079	0.1337	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0079	0.1337	0.4054
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0045	0.0359	0.0453
Echinococcus granulosus	cathepsin L	0.0079	0.1337	0.1317
Giardia lamblia	Cathepsin B precursor	0.0118	0.2468	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0145	0.3265	1
Brugia malayi	cathepsin L-like precursor	0.01	0.195	0.246
Loa Loa (eye worm)	hypothetical protein	0.0306	0.793	1
Loa Loa (eye worm)	hypothetical protein	0.01	0.195	0.246
Brugia malayi	cathepsin B-like cysteine proteinase	0.0306	0.793	1
Brugia malayi	Papain family cysteine protease containing protein	0.0145	0.3265	0.4117
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0079	0.1337	0.1337
Brugia malayi	Cathepsin L-like precursor	0.0145	0.3265	0.4117
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0145	0.3265	0.3249
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0145	0.3265	1
Entamoeba histolytica	cysteine proteinase, putative	0.01	0.195	0.5946
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0125	0.2681	0.2681
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0383	0.0361
Loa Loa (eye worm)	cysteine protease	0.0145	0.3265	0.4117
Trypanosoma cruzi	cysteine peptidase, putative	0.0145	0.3265	0.41
Entamoeba histolytica	cysteine protease, putative	0.0079	0.1337	0.4054
Brugia malayi	Papain family cysteine protease containing protein	0.0079	0.1337	0.1686
Echinococcus multilocularis	geminin	0.0164	0.3795	0.3781
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0034	0.0023	0.0023
Giardia lamblia	Cathepsin B precursor	0.0118	0.2468	1
Entamoeba histolytica	cysteine proteinase 1, putative	0.0079	0.1337	0.4054
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0442	0.0558
Schistosoma mansoni	cathepsin C	0.0034	0.0023	0.0023
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0023	0.0029
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0145	0.3265	1
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0079	0.1337	0.1662
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0383	0.0383
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0378	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0145	0.3265	1
Brugia malayi	Cathepsin L-like precursor	0.0145	0.3265	0.4117
Brugia malayi	Papain family cysteine protease containing protein	0.0034	0.0023	0.0029
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0378	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0145	0.3265	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0145	0.3265	1
Loa Loa (eye worm)	hypothetical protein	0.0145	0.3265	0.4117
Schistosoma mansoni	hypothetical protein	0.0164	0.3795	0.3795
Leishmania major	cathepsin L-like protease	0.0145	0.3265	1
Plasmodium vivax	vivapain-2	0.0145	0.3265	1
Onchocerca volvulus		0.0145	0.3265	1
Onchocerca volvulus	Cathepsin L homolog	0.0145	0.3265	1
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0034	0.0023	0.0029
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0079	0.1337	0.4054
Brugia malayi	cathepsin L-like cysteine proteinase, identical	0.0045	0.0359	0.0453
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0145	0.3265	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0145	0.3265	1
Echinococcus multilocularis	serotonin receptor	0.0125	0.2681	0.2665
Schistosoma mansoni	cathepsin S (C01 family)	0.0034	0.0023	0.0023
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0048	0.0442	0.0558
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0118	0.2468	0.3093
Loa Loa (eye worm)	hypothetical protein	0.01	0.195	0.246
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0034	0.0023	0.0029
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0034	0.0023	0.0029
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0118	0.2468	0.2468
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0034	0.0023	0.0023
Entamoeba histolytica	cysteine protease, putative	0.0145	0.3265	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0145	0.3265	1
Brugia malayi	Cathepsin L-like precursor	0.0045	0.0359	0.0453
Entamoeba histolytica	cysteine proteinase, putative	0.0079	0.1337	0.4054
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0145	0.3265	0.3249
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0359	0.0453
Entamoeba histolytica	cysteine protease, putative	0.0079	0.1337	0.4054
Entamoeba histolytica	cysteine protease, putative	0.0079	0.1337	0.4054
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0383	0.0361
Leishmania major	cysteine peptidase A (CPA)	0.0145	0.3265	1
Brugia malayi	cathepsin L-like cysteine proteinase	0.0034	0.0023	0.0029
Brugia malayi	cathepsin F-like cysteine proteinase	0.0045	0.0359	0.0453
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.01	0.195	0.5946
Onchocerca volvulus		0.0145	0.3265	1
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0145	0.3265	1
Entamoeba histolytica	cysteine protease, putative	0.0079	0.1337	0.4054
Onchocerca volvulus		0.0145	0.3265	1
Toxoplasma gondii	cathepsin CPL	0.0145	0.3265	1
Entamoeba histolytica	cysteine proteinase, putative	0.0145	0.3265	1
Loa Loa (eye worm)	fibroinase	0.0145	0.3265	0.4117
Schistosoma mansoni	cathepsin F (C01 family)	0.0145	0.3265	0.3265
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0145	0.3265	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0145	0.3265	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0383	0.0383
Echinococcus multilocularis	cysteine protease	0.0145	0.3265	0.3249
Trypanosoma cruzi	cysteine peptidase, putative	0.0045	0.0359	0.0425
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0034	0.0023	0.0023
Brugia malayi	cathepsin F-like cysteine proteinase	0.0034	0.0023	0.0029
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0145	0.3265	0.4117
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0048	0.0442	0.0558
Leishmania major	cathepsin L-like protease	0.0145	0.3265	1
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0118	0.2468	0.5868
Plasmodium vivax	vivapain-2	0.0145	0.3265	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0145	0.3265	1
Brugia malayi	Cathepsin L-like precursor	0.0145	0.3265	0.4117
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0145	0.3265	1
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.0034	0.0023	0.0029
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0118	0.2468	0.7543
Giardia lamblia	Cathepsin B precursor	0.0118	0.2468	1
Schistosoma mansoni	cathepsin B (C01 family)	0.0034	0.0023	0.0023
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0145	0.3265	1
Trypanosoma cruzi	cysteine proteinase, putative	0.0079	0.1337	0.1662
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0359	0.0453
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0034	0.0023	0.0023
Loa Loa (eye worm)	ctsf protein	0.0145	0.3265	0.4117
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0145	0.3265	1
Plasmodium vivax	unspecified product	0.0045	0.0359	0.1037
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0306	0.793	0.793
Onchocerca volvulus	Cathepsin F homolog	0.0145	0.3265	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0145	0.3265	0.41
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0359	0.0453
Onchocerca volvulus		0.0145	0.3265	1
Echinococcus granulosus	biogenic amine 5HT receptor	0.0125	0.2681	0.2665
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0079	0.1337	0.4054
Echinococcus multilocularis	cathepsin L cysteine protease	0.0145	0.3265	0.3249
Leishmania major	cathepsin L-like protease	0.0145	0.3265	1
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0034	0.0023	0.0029
Echinococcus granulosus	geminin	0.0164	0.3795	0.3781
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0046	0.0383	0.0483
Onchocerca volvulus		0.01	0.195	0.5946
Entamoeba histolytica	cysteine proteinase, putative	0.0145	0.3265	1
Brugia malayi	cathepsin L precursor	0.0034	0.0023	0.0029
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0145	0.3265	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0145	0.3265	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0145	0.3265	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0145	0.3265	1
Plasmodium vivax	unspecified product	0.0079	0.1337	0.4054
Schistosoma mansoni	cathepsin s	0.0045	0.0359	0.0359
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.0306	0.793	0.793
Brugia malayi	Cathepsin L-like precursor	0.0145	0.3265	0.4117
Loa Loa (eye worm)	hypothetical protein	0.01	0.195	0.246
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0306	0.793	1
Entamoeba histolytica	cysteine protease, putative	0.0079	0.1337	0.4054
Entamoeba histolytica	cysteine protease, putative	0.0079	0.1337	0.4054
Schistosoma mansoni	cathepsin F (C01 family)	0.0145	0.3265	0.3265
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0023	0.0029
Entamoeba histolytica	cysteine protease, putative	0.0079	0.1337	0.4054
Echinococcus granulosus	cathepsin b	0.0306	0.793	0.7925
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0383	0.0383
Entamoeba histolytica	cysteine protease, putative	0.0079	0.1337	0.4054
Trypanosoma cruzi	cysteine peptidase, putative	0.0145	0.3265	0.41
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0023	0.0029
Loa Loa (eye worm)	cathepsin B	0.0118	0.2468	0.3113
Leishmania major	cathepsin L-like protease	0.0145	0.3265	1
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0079	0.1337	0.1337
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0145	0.3265	1
Brugia malayi	Cathepsin L-like precursor	0.0145	0.3265	0.4117
Echinococcus granulosus	cathepsin l1	0.01	0.195	0.1932
Echinococcus granulosus	cathepsin l1	0.0145	0.3265	0.3249
Trypanosoma cruzi	cysteine proteinase, putative	0.0079	0.1337	0.1662
Entamoeba histolytica	cysteine protease, putative	0.0079	0.1337	0.4054
Brugia malayi	Papain family cysteine protease containing protein	0.0034	0.0023	0.0029
Echinococcus multilocularis	cathepsin b	0.0306	0.793	0.7925
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0145	0.3265	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0145	0.3265	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0079	0.1337	0.1662
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0306	0.793	0.793
Brugia malayi	Papain family cysteine protease containing protein	0.0079	0.1337	0.1686
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0145	0.3265	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0145	0.3265	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0145	0.3265	1
Entamoeba histolytica	cysteine proteinase, putative	0.0079	0.1337	0.4054
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0145	0.3265	1
Echinococcus multilocularis	cathepsin L cysteine protease	0.0145	0.3265	0.3249
Brugia malayi	cahepsin L-like non-peptiedase homolog	0.0034	0.0023	0.0029
Brugia malayi	fibroinase precursor	0.0034	0.0023	0.0029
Leishmania major	cathepsin L-like protease	0.0145	0.3265	1
Trypanosoma cruzi	cruzipain precursor, putative	0.0145	0.3265	0.41
Echinococcus multilocularis	cathepsin b	0.0306	0.793	0.7925
Onchocerca volvulus		0.0145	0.3265	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.01	0.195	0.5946
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0145	0.3265	1
Echinococcus multilocularis	serotonin receptor	0.0125	0.2681	0.2665
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0145	0.3265	1
Entamoeba histolytica	cysteine protease, putative	0.0079	0.1337	0.4054
Loa Loa (eye worm)	hypothetical protein	0.0125	0.2681	0.3382
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0145	0.3265	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0145	0.3265	1
Echinococcus multilocularis	cathepsin L	0.0079	0.1337	0.1317
Schistosoma mansoni	hypothetical protein	0.0164	0.3795	0.3795
Leishmania major	cathepsin L-like protease	0.0145	0.3265	1
Schistosoma mansoni	cathepsin F (C01 family)	0.01	0.195	0.195
Trypanosoma cruzi	cysteine protease, putative	0.0079	0.1337	0.1662
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0034	0.0023	0.0023
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0034	0.0023	0.0023
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0023	0.0029
Leishmania major	cathepsin L-like protease	0.0145	0.3265	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0034	0.0023	0.0023
Onchocerca volvulus		0.0145	0.3265	1
Entamoeba histolytica	cysteine proteinase, putative	0.0079	0.1337	0.4054
Entamoeba histolytica	cysteine protease, putative	0.0079	0.1337	0.4054
Brugia malayi	Cathepsin L-like precursor	0.01	0.195	0.246
Brugia malayi	Cathepsin L-like precursor	0.0145	0.3265	0.4117
Brugia malayi	Cathepsin L-like cysteine proteinase	0.01	0.195	0.246
Echinococcus granulosus	cathepsin b	0.0306	0.793	0.7925
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0145	0.3265	1
Loa Loa (eye worm)	hypothetical protein	0.0125	0.2681	0.3382
Brugia malayi	Cathepsin L-like precursor	0.01	0.195	0.246
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0023	0.0029
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.0034	0.0023	0.0023
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0145	0.3265	1
Plasmodium vivax	vivapain-1	0.0079	0.1337	0.4054
Entamoeba histolytica	cysteine protease, putative	0.0079	0.1337	0.4054
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0079	0.1337	0.1337
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0145	0.3265	1
Toxoplasma gondii	cathepsin B	0.0118	0.2468	0.7543
Entamoeba histolytica	cysteine proteinase 2	0.0079	0.1337	0.4054
Echinococcus granulosus	cathepsin L cysteine protease	0.0079	0.1337	0.1317
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0048	0.0442	0.0558
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0145	0.3265	0.3249
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0306	0.793	0.793
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.0034	0.0023	0.0023
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0145	0.3265	1
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0145	0.3265	0.4117
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0383	0.0361
Trypanosoma cruzi	cruzipain precursor, putative	0.0045	0.0359	0.0425

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 876048