Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | insulin receptor | 0.0185 | 0.0014 | 0.0145 |
Schistosoma mansoni | tyrosine kinase | 0.058 | 0.0984 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0312 | 0.0325 | 0.32 |
Schistosoma mansoni | tyrosine kinase | 0.0308 | 0.0316 | 0.3117 |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) | 0.4251 | 1 | 0.5 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0185 | 0.0014 | 0.0145 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0312 | 0.0325 | 0.32 |
Schistosoma mansoni | tyrosine kinase | 0.0308 | 0.0316 | 0.3117 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.058 | 0.0984 | 1 |
Plasmodium vivax | beta-ketoacyl-acyl carrier protein synthase III precursor, putative | 0.4251 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0308 | 0.0316 | 0.3117 |
Schistosoma mansoni | tyrosine kinase | 0.0312 | 0.0325 | 0.32 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.4251 | 1 | 0.5 |
Echinococcus granulosus | epidermal growth factor receptor | 0.058 | 0.0984 | 1 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.4251 | 1 | 0.5 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.4251 | 1 | 0.5 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0552 | 0.0915 | 0.5 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0552 | 0.0915 | 0.5 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0552 | 0.0915 | 0.5 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0552 | 0.0915 | 0.5 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.058 | 0.0984 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0312 | 0.0325 | 0.3299 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.058 | 0.0984 | 1 |
Mycobacterium ulcerans | beta-ketoacyl synthase-like protein | 0.4251 | 1 | 0.5 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0312 | 0.0325 | 0.32 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0552 | 0.0915 | 0.5 |
Plasmodium falciparum | beta-ketoacyl-ACP synthase III | 0.4251 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.