Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tyrosine kinase | 0.0488 | 0.0512 | 0.3405 |
Schistosoma mansoni | tyrosine kinase | 0.0488 | 0.0512 | 0.3405 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0919 | 0.1503 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0295 | 0.0067 | 0.0398 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0295 | 0.0067 | 0.0443 |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) | 0.4616 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0494 | 0.0526 | 0.3501 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.4616 | 1 | 0.5 |
Entamoeba histolytica | fatty acid elongase, putative | 0.06 | 0.0768 | 0.5 |
Echinococcus multilocularis | 0.0284 | 0.0043 | 0.0286 | |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.4616 | 1 | 0.5 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0919 | 0.1503 | 1 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.4616 | 1 | 0.5 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0295 | 0.0067 | 0.0443 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0919 | 0.1503 | 1 |
Entamoeba histolytica | fatty acid elongase, putative | 0.06 | 0.0768 | 0.5 |
Entamoeba histolytica | fatty acid elongase, putative | 0.06 | 0.0768 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0295 | 0.0067 | 0.0443 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0295 | 0.0067 | 0.0398 |
Echinococcus multilocularis | insulin receptor | 0.0295 | 0.0067 | 0.0443 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0919 | 0.1503 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0494 | 0.0526 | 0.3501 |
Plasmodium vivax | beta-ketoacyl-acyl carrier protein synthase III precursor, putative | 0.4616 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0494 | 0.0526 | 0.3501 |
Schistosoma mansoni | tyrosine kinase | 0.0488 | 0.0512 | 0.3405 |
Echinococcus granulosus | insulin receptor | 0.0295 | 0.0067 | 0.0443 |
Schistosoma mansoni | tyrosine kinase | 0.0295 | 0.0067 | 0.0443 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0494 | 0.0526 | 0.3501 |
Entamoeba histolytica | fatty acid elongase, putative | 0.06 | 0.0768 | 0.5 |
Entamoeba histolytica | fatty acid elongase, putative | 0.06 | 0.0768 | 0.5 |
Plasmodium falciparum | beta-ketoacyl-ACP synthase III | 0.4616 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0919 | 0.1503 | 1 |
Mycobacterium ulcerans | beta-ketoacyl synthase-like protein | 0.4616 | 1 | 0.5 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0494 | 0.0526 | 0.3501 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.